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View Structure Prediction Details

Protein: LAM6_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 693 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LAM6_YEAST.

Description E-value Query
Range
Subject
Range
LAM6_YEAST - Membrane-anchored lipid-binding protein LAM6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
YLR072W - Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytopla...
0.0 [1..693] [1..693]
gi|26665873, gi|... - gi|26665873|ref|NP_082174.2| GRAM domain containing 1A [Mus musculus], gi|17391321|gb|AAH18554.1| Gr...
0.0 [158..652] [11..556]
gi|24308247, gi|... - gi|24308247|ref|NP_065946.1| hypothetical protein LOC57655 [Homo sapiens], gi|15559417|gb|AAH14077.1...
0.0 [156..652] [9..559]
SPBC20F10.07 - GRAM domain protein
YGZ7_SCHPO - Uncharacterized membrane protein C20F10.07 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN...
0.0 [112..571] [149..593]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-93 [100..533] [109..540]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWGDSMRELG DAMDNELNAV KPVVEEGGMD GARKFIKGKS FQKSSTEHML ISPGRDGSVP  60
   61 LNGLKSSPAD PHLSDVNSIL DNHRGGGETA LTSVNNIIMA TSTNGDSDGV DG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [113-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAKRPSISNC SSRSSFFDTV LSTFSLKSNS QDTVTNEVKN IEVQFASEEA NKKFRQMFKP  60
   61 LAPNTRLITD YFCYFHREFP YQGRIYLSNT HLCFNSTVLN WMAKLQIPLN EIKYLDKVTT 120
  121 NSSAISVETV TNRYTFSGFI ARDEVFQLIT RVWSKENLTN IND

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 28.142668
Match: PF02893
Description: GRAM domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 1.37262912917599 bayes_pls_golite062009
protein binding 1.01923599216718 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [276-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLEVDERVSK KKGISSTPSS IFNNVSTNAY NDFISTTTTE PTSRASYMSE NDMLIEEAIR  60
   61 SVDDYMGTPR ASPSSSSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [354-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSSSSSLGS STTYYCRPVY RLKPNAPFQY EGPFHVQETM DFPYKPEANN EYVLLERQFS  60
   61 VPPGLLFIMM FNEDNPVFEL SFLKTQDSSN ISHIGTFEKV NKDGQHYREF QYTKQLHFPV 120
  121 GPKSTNCEVA EILLHCDWER YINVLSITRT PNVPSGTSFS TRTRYMFRWD DQGQGCILKI 180
  181 SFWVDWNASS WIKPMVESNC KNGQISATKD LVKLVEEFVE KYVELSKEKA DTLKP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 0.240804061374211 bayes_pls_golite062009
catalytic activity 0.0521786759115963 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [589-693]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSVTSFGSP RKVAAPELTM VQPESKPEAE AEISEIGSDR WRFNWVNIII LVLLVLNLLY  60
   61 LMKLNKKMDK LTNLMTHKDE VVAHATLLDI PAKVQWSRPR RGDVL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.807 0.886 cytoplasm a.1.1 Globin-like


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