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View Structure Prediction Details

Protein: ceh-16
Organism: Caenorhabditis elegans
Length: 187 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ceh-16.

Description E-value Query
Range
Subject
Range
gi|47230602 - gi|47230602|emb|CAF99795.1| unnamed protein product [Tetraodon nigroviridis]
125.0 [0..3] [175..195]

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Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILKFGIERI LSSPYPCPSP TISTPATSPS SISPTFASPN GTPNIASSMY PAWVFSTRYS  60
   61 DRPSAGPRHR KSRKREST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [79-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSSGSSEEEK RPRTAFTGDQ LDRLKTEFRE SRYLTEKRRQ ELAHELGLNE SQIKIWFQNK  60
   61 RAKLKKSTSS VPRDRCSSVT PNPHNHPSIH GGYQLMAQLA KVQARAYMP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.39794
Match: 1homA
Description: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.57523737355937 bayes_pls_golite062009
DNA binding 3.00143272905695 bayes_pls_golite062009
nucleic acid binding 2.89825020286436 bayes_pls_golite062009
transcription factor activity 2.53664874743748 bayes_pls_golite062009
transcription repressor activity 1.84054423341798 bayes_pls_golite062009
binding 1.68817361068715 bayes_pls_golite062009
sequence-specific DNA binding 1.56629498736977 bayes_pls_golite062009
transcription activator activity 1.26247803652791 bayes_pls_golite062009
protein binding 1.16239587634422 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.14821760889085 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle