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View Structure Prediction Details

Protein: CE37427
Organism: Caenorhabditis elegans
Length: 614 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE37427.

Description E-value Query
Range
Subject
Range
CE37569 - status:Confirmed UniProt:Q65XY0 protein_id:AAU87813.1
330.0 [0..108] [614..8]

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Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVAAPEEHE KVVTVCGELV RSLDANGKEM VIRREVSVTE TRESRDTSLK VEIPSEQEIE  60
   61 LPVIVHDKPK LIKQEVSVVE PLELQESVES TELSVTSKES TEQLPSKDSL DSPSGSTSRA 120
  121 GSSVS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [126-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATASPMHRNT TSQHGGLFVS APGKIILFGE HAVVYGRTAI AGSIDLRTYV SLYTSADGRI  60
   61 YLSLPDLGVE KTWMLKDLLK AADRLAAEYP IEEDQPPSLE ILVPIARKLS GSCEDQCGVQ 120
  121 HLAILAFWYL LLGVAHRKRD LLAVKATVRF KLPSCVGLGS SGAYCVCIAT SLLQTAGLIP 180
  181 PPSIVADEQG NLTWEEDHLD IIRKWATAAE SLIHGRASGL DAAVCTFGGV ASFKPGHRIE 240
  241 HLKNLPDLRV ILVNSKVERN TARMVQTVKE RLKKFPEVVD AMFGSIDAIS LDAAKILHRP 300
  301 LLEENGGGDT GSTVQENGLG PFGGNMVEQD HHSLQPTRTA SVRSSSLSSY VGGGKRNSSA 360
  361 SVISATSEKG ENVDTFSKLN DLCRINNQLL IA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.39794
Match: 1kvkA
Description: Mevalonate kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.143381257585741 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [518-614]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGVGHPKVDL ICTTLARYGI HPKMTGAGGG GSVFAFLKPN TPQTLLDMID GELRSHGFEV  60
   61 WQPPLGGPGV VEHQTRPELF QTPVSSTQCS TPASKHK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.81
Match: 2a2cA
Description: x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle