YRC Public Data Repository - Protein Structure Prediction

Protein:	CLPP_SALTY
Organism:	Salmonella enterica subsp. enterica serovar Typhimurium
Length:	207 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLPP_SALTY.

Description	E-value	Query Range	Subject Range
gi\|77974303 - gi\|77974303\|ref\|ZP_00829844.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Yersinia fr... gi\|238710696, gi... - gi\|238751006\|ref\|ZP_04612502.1\| ATP-dependent Clp protease proteolytic subunit [Yersinia rohdei ATCC...	3.0E-76	[1..207]	[1..207]
CLPP_YERE8 - ATP-dependent Clp protease proteolytic subunit OS=Yersinia enterocolitica serotype O:8 / biotype 1B ... CLPP_YEREN - ATP-dependent Clp protease proteolytic subunit OS=Yersinia enterocolitica GN=clpP PE=3 SV=1	6.0E-76	[1..207]	[1..207]
gi\|62179060, gi\|... - gi\|62179060\|ref\|YP_215477.1\| ATP-dependent Clp protease proteolytic subunit [Salmonella enterica sub...	6.0E-76	[1..207]	[40..246]
gi\|77979391 - gi\|77979391\|ref\|ZP_00834810.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Yersinia in...	4.0E-75	[1..207]	[1..207]
gi\|162419837, gi... - gi\|77635225\|ref\|ZP_00797312.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Yersinia pe... CLPP_YERP3 - ATP-dependent Clp protease proteolytic subunit OS=Yersinia pseudotuberculosis serotype O:1b (strain ... gi\|89103165, gi\|... - gi\|89103165\|ref\|ZP_01175755.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Yersinia pe... gi\|167421692, gi... - gi\|167421692\|ref\|ZP_02313445.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Yersinia pesti... CLPP_YERPA - ATP-dependent Clp protease proteolytic subunit OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=cl... gi\|167051461, gi... - gi\|167398957\|ref\|ZP_02304481.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Yersinia pesti... CLPP_YERPN - ATP-dependent Clp protease proteolytic subunit OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=c... gi\|170025451, gi... - gi\|170025451\|ref\|YP_001721956.1\| ATP-dependent Clp protease proteolytic subunit [Yersinia pseudotube... gi\|167423463, gi... - gi\|167423463\|ref\|ZP_02315216.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Yersinia pesti... gi\|22124934, gi\|... - gi\|22124934\|ref\|NP_668357.1\| ATP-dependent Clp protease proteolytic subunit [Yersinia pestis KIM], g... gi\|186697352, gi... - gi\|186894326\|ref\|YP_001871438.1\| ATP-dependent Clp protease proteolytic subunit [Yersinia pseudotube... CLPP_YERPE - ATP-dependent Clp protease proteolytic subunit OS=Yersinia pestis GN=clpP PE=3 SV=1 CLPP_YERPS - ATP-dependent Clp protease proteolytic subunit OS=Yersinia pseudotuberculosis serotype I (strain IP3... gi\|45435480, gi\|... - gi\|45440623\|ref\|NP_992162.1\| ATP-dependent Clp protease proteolytic subunit [Yersinia pestis biovar ... CLPP_YERPS - ATP-dependent Clp protease proteolytic subunit OS=Yersinia pseudotuberculosis GN=clpP PE=3 SV=1 gi\|16123319, gi\|... - gi\|218930187\|ref\|YP_002348062.1\| ATP-dependent Clp protease proteolytic subunit [Yersinia pestis CO9... gi\|165921541, gi... - gi\|165926613\|ref\|ZP_02222445.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Yersinia pesti... gi\|166212961, gi... - gi\|166212961\|ref\|ZP_02238996.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Yersinia pesti... gi\|166010967, gi... - gi\|166010967\|ref\|ZP_02231865.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Yersinia pesti... gi\|229695127, gi... - gi\|229838761\|ref\|ZP_04458920.1\| proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine ... gi\|229701008, gi... - gi\|229896085\|ref\|ZP_04511255.1\| proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine ... gi\|229899329, gi... - gi\|229899329\|ref\|ZP_04514472.1\| proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine ... gi\|149364997, gi... - gi\|149364997\|ref\|ZP_01887032.1\| ATP-dependent Clp protease proteolytic subunit ClpP [Yersinia pestis... CLPP_YERPP - ATP-dependent Clp protease proteolytic subunit OS=Yersinia pestis (strain Pestoides F) GN=clpP PE=3 ...	4.0E-75	[1..207]	[1..207]
CLPP_SALPA - ATP-dependent Clp protease proteolytic subunit OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42)... CLPP_SALPK - ATP-dependent Clp protease proteolytic subunit OS=Salmonella paratyphi A (strain AKU_12601) GN=clpP ... CLPP_SALPA - ATP-dependent Clp protease proteolytic subunit OS=Salmonella paratyphi A GN=clpP PE=3 SV=1	5.0E-75	[1..207]	[1..207]
gi\|238715487, gi... - gi\|77956937\|ref\|ZP_00821009.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Yersinia be...	8.0E-75	[1..207]	[1..207]
CLPP_SHIFL - ATP-dependent Clp protease proteolytic subunit OS=Shigella flexneri GN=clpP PE=3 SV=1 CLPP_ECOL6 - ATP-dependent Clp protease proteolytic subunit OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 70092... gi\|30061939, gi\|... - gi\|30061939\|ref\|NP_836110.1\| ATP-dependent Clp protease proteolytic subunit [Shigella flexneri 2a st... CLPP_ECO57 - ATP-dependent Clp protease proteolytic subunit OS=Escherichia coli O157:H7 GN=clpP PE=3 SV=1 CLPP_ECOL6 - ATP-dependent Clp protease proteolytic subunit OS=Escherichia coli O6 GN=clpP PE=3 SV=1 EG10158 - proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine proteases / Proteolytic subunit ... gi\|12513299, gi\|... - gi\|15800167\|ref\|NP_286179.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli O157:H... CLPP_ECOK1 - ATP-dependent Clp protease proteolytic subunit OS=Escherichia coli O1:K1 / APEC GN=clpP PE=3 SV=1 gi\|124531646, gi... - gi\|124531646\|ref\|ZP_01701834.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia co... EG10158 - proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine proteases / Proteolytic subunit ... CLPP_ECOLI - ATP-dependent Clp protease proteolytic subunit precursor (EC 3.4.21.92) (Endopeptidase Clp) (Caseino... gi\|218357436, gi... - gi\|218549895\|ref\|YP_002383686.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia ferguso... gi\|218359772, gi... - gi\|218553004\|ref\|YP_002385917.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli IA... gi\|218364116, gi... - gi\|218557347\|ref\|YP_002390260.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli S8... gi\|218425865, gi... - gi\|218688301\|ref\|YP_002396513.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli ED... gi\|218350632, gi... - gi\|218693900\|ref\|YP_002401567.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli 55... gi\|218368637, gi... - gi\|218698651\|ref\|YP_002406280.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli IA... gi\|218430818, gi... - gi\|218703721\|ref\|YP_002411240.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli UM... gi\|193064129, gi... - gi\|75257917\|ref\|ZP_00729395.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Escherichia... CLPP_SHISS - ATP-dependent Clp protease proteolytic subunit OS=Shigella sonnei (strain Ss046) GN=clpP PE=3 SV=1 CLPP_ECOHS - ATP-dependent Clp protease proteolytic subunit OS=Escherichia coli O9:H4 (strain HS) GN=clpP PE=3 SV... gi\|75208055 - gi\|75208055\|ref\|ZP_00708460.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Escherichia... gi\|85674577, gi\|... - gi\|89107307\|ref\|AP_001087.1\| proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine pro... gi\|56383209, gi\|... - gi\|56479658\|ref\|NP_706331.2\| ATP-dependent Clp protease proteolytic subunit [Shigella flexneri 2a st... CLPP_SHIDS - ATP-dependent Clp protease proteolytic subunit OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=... CLPP_SHIBS - ATP-dependent Clp protease proteolytic subunit OS=Shigella boydii serotype 4 (strain Sb227) GN=clpP ... CLPP_ECO24 - ATP-dependent Clp protease proteolytic subunit OS=Escherichia coli O139:H28 (strain E24377A / ETEC) ... gi\|189358046, gi... - gi\|189358046\|gb\|EDU76465.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia coli O... gi\|191174674, gi... - gi\|191174674\|ref\|ZP_03036146.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia co... gi\|195938496 - gi\|195938496\|ref\|ZP_03083878.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli O15... gi\|208729341, gi... - gi\|208809540\|ref\|ZP_03251877.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia co... gi\|208815859, gi... - gi\|208815859\|ref\|ZP_03257038.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia co... gi\|208737157, gi... - gi\|208822964\|ref\|ZP_03263282.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia co... gi\|209917654, gi... - gi\|209917654\|ref\|YP_002291738.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli SE... gi\|254791621, gi... - gi\|254791621\|ref\|YP_003076458.1\| proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine... gi\|215485518, gi... - gi\|215485518\|ref\|YP_002327949.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli O1... gi\|254160506, gi... - gi\|254160506\|ref\|YP_003043614.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli B ... gi\|217326412, gi... - gi\|217326412\|ref\|ZP_03442496.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia co... gi\|254287310, gi... - gi\|254287310\|ref\|YP_003053058.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli BL... gi\|189362475, gi... - gi\|189362475\|gb\|EDU80894.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia coli O... gi\|187766815, gi... - gi\|187766815\|gb\|EDU30659.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia coli O... gi\|251783945, gi... - gi\|251783945\|ref\|YP_002998249.1\| hypothetical protein B21_00392 [Escherichia coli BL21], gi\|24237621... gi\|189003087, gi... - gi\|189003087\|gb\|EDU72073.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia coli O... gi\|238899725, gi... - gi\|238899725\|ref\|YP_002925521.1\| proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine... gi\|189373600, gi... - gi\|189373600\|gb\|EDU92016.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia coli O... gi\|227838638, gi... - gi\|227884552\|ref\|ZP_04002357.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli 839... gi\|170080023, gi... - gi\|170080023\|ref\|YP_001729343.1\| proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine... gi\|170683276, gi... - gi\|170683276\|ref\|YP_001742581.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia c... gi\|187428295, gi... - gi\|187731303\|ref\|YP_001879148.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Shigella boyd... CLPP_ECOLC - ATP-dependent Clp protease proteolytic subunit OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Cr... gi\|188487796, gi... - gi\|188492597\|ref\|ZP_02999867.1\| ATP-dependent Clp protease, proteolytic subunit ClpP [Escherichia co... CLPP_ECOUT - ATP-dependent Clp protease proteolytic subunit OS=Escherichia coli (strain UTI89 / UPEC) GN=clpP PE=... gi\|15829745, gi\|... - gi\|15829745\|ref\|NP_308518.1\| ATP-dependent Clp protease proteolytic subunit [Escherichia coli O157:H... CLPP_ECOL5 - ATP-dependent Clp protease proteolytic subunit OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN... CLPP_SHIF8 - ATP-dependent Clp protease proteolytic subunit OS=Shigella flexneri serotype 5b (strain 8401) GN=clp...	9.0E-75	[1..207]	[1..207]
CLPP_PHOLL - ATP-dependent Clp protease proteolytic subunit OS=Photorhabdus luminescens subsp. laumondii GN=clpP ... CLPP_PHOLL - ATP-dependent Clp protease proteolytic subunit OS=Photorhabdus luminescens subsp. laumondii (strain ...	6.0E-74	[1..207]	[1..207]
gi\|90579278, gi\|... - gi\|90579278\|ref\|ZP_01235088.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio angustum S14],... gi\|89073230, gi\|... - gi\|89073230\|ref\|ZP_01159760.1\| ATP-dependent Clp protease proteolytic subunit [Photobacterium sp. SK...	6.0E-74	[1..207]	[1..207]

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Predicted Domain #1

Region A:
Residues: [1-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYSGERDNL APHMALVPMV IEQTSRGERS FDIYSRLLKE RVIFLTGQVE DHMANLIVAQ  60
   61 MLFLEAENPE KDIYLYINSP GGVITAGMSI YDTMQFIKPD VSTICMGQAA SMGAFLLTAG 120
  121 AKGKRFCLPN SRVMIHQPLG GYQGQATDIE IHAREILKVK GRMNELMAHH TGQSLEQIER 180
  181 DTERDRFLSA PEAVEYGLVD SILTHRN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.39794
Match:	1tyfA
Description:	Clp protease, ClpP subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.46154163027498	bayes_pls_golite062009
CoA carboxylase activity	0.939626895227199	bayes_pls_golite062009
acetyl-CoA carboxylase activity	0.764444938444292	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	0.621229080200493	bayes_pls_golite062009
enoyl-CoA hydratase activity	0.620657548610719	bayes_pls_golite062009
hydrolase activity	0.534319520590169	bayes_pls_golite062009
binding	0.367666848528835	bayes_pls_golite062009
ligase activity	0.32092496884003	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: