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View Structure Prediction Details

Protein: TFB4_ARATH
Organism: Arabidopsis thaliana
Length: 301 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFB4_ARATH.

Description E-value Query
Range
Subject
Range
TF2H3_RAT - General transcription factor IIH subunit 3 OS=Rattus norvegicus GN=Gtf2h3 PE=2 SV=1
378.0 [0..10] [284..5]

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Predicted Domain #1
Region A:
Residues: [1-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAIASKQYS DDVSLLVLLL DTNPLFWSTT SITFSQFLSH VLAFLNAVLG LNQLNQVVVI  60
   61 ATGYSSCDYI YDSSLTSNHG NFESNGTGMP AIFGSLLKKL EEFVTKDEEL SKEEVSEDRI 120
  121 PSCLLSGSLS MALCYIQRVF RSGHLHPQPR ILCLQGSPDG PEQYVAVMNS IFSAQRLMVP 180
  181 IDSCYIGVQN SAFLQQASYI TGGVHHTPKQ LDGLFQYLTT IFATDLHSRG FVQLPKPIGV 240
  241 DFRASCFCHK KTIDMGYICS VCLSIFCEHH KKCSTCGSVF GQSKLDDASS ASDKKRKAPS 300
  301 T

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.951
Match: 1txvB
Description: Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.68315152218267 bayes_pls_golite062009
nucleic acid binding 2.10023916482665 bayes_pls_golite062009
DNA binding 1.9295508897092 bayes_pls_golite062009
protein binding 1.42792331963866 bayes_pls_golite062009
hydrolase activity 0.589248272940562 bayes_pls_golite062009
structure-specific DNA binding 0.446181458443121 bayes_pls_golite062009
protein complex binding 0.0576912134524816 bayes_pls_golite062009
catalytic activity 0.0380261580236634 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle