YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|229841387, gi...
Organism:	Yersinia pestis biovar Orientalis str. PEXU2
Length:	401 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|229841387, gi....

Description	E-value	Query Range	Subject Range
PNCB_PSEPF - Nicotinate phosphoribosyltransferase OS=Pseudomonas fluorescens (strain Pf0-1) GN=pncB PE=3 SV=1	0.0	[4..401]	[6..404]
gi\|21959646, gi\|... - gi\|22126635\|ref\|NP_670058.1\| nicotinate phosphoribosyltransferase [Yersinia pestis KIM], gi\|21959646... gi\|45441007, gi\|... - gi\|45441007\|ref\|NP_992546.1\| nicotinate phosphoribosyltransferase [Yersinia pestis biovar Microtus s... gi\|167050764, gi... - gi\|167400056\|ref\|ZP_02305574.1\| nicotinate phosphoribosyltransferase [Yersinia pestis biovar Antiqua... gi\|167057195, gi... - gi\|167424346\|ref\|ZP_02316099.1\| nicotinate phosphoribosyltransferase [Yersinia pestis biovar Mediaev... gi\|166010362, gi... - gi\|166010362\|ref\|ZP_02231260.1\| nicotinate phosphoribosyltransferase [Yersinia pestis biovar Antiqua... gi\|166207169, gi... - gi\|166211398\|ref\|ZP_02237433.1\| nicotinate phosphoribosyltransferase [Yersinia pestis biovar Antiqua... gi\|165938920, gi... - gi\|165938920\|ref\|ZP_02227473.1\| nicotinate phosphoribosyltransferase [Yersinia pestis biovar Orienta...	0.0	[1..401]	[16..416]
gi\|89104666 - gi\|89104666\|ref\|ZP_01177203.1\| COG1488: Nicotinic acid phosphoribosyltransferase [Yersinia pestis bi... gi\|165924651, gi... - gi\|165924651\|ref\|ZP_02220483.1\| nicotinate phosphoribosyltransferase [Yersinia pestis biovar Orienta... gi\|166962183, gi... - gi\|167419442\|ref\|ZP_02311195.1\| nicotinate phosphoribosyltransferase [Yersinia pestis biovar Orienta... gi\|145211250, gi... - gi\|145599554\|ref\|YP_001163630.1\| nicotinate phosphoribosyltransferase [Yersinia pestis Pestoides F],... gi\|170024872, gi... - gi\|170024872\|ref\|YP_001721377.1\| nicotinate phosphoribosyltransferase [Yersinia pseudotuberculosis Y... gi\|186697882, gi... - gi\|186894856\|ref\|YP_001871968.1\| nicotinate phosphoribosyltransferase [Yersinia pseudotuberculosis P... gi\|117674106, gi... - gi\|77632397\|ref\|ZP_00794983.1\| COG1488: Nicotinic acid phosphoribosyltransferase [Yersinia pseudotub... gi\|108812725, gi... - gi\|108812725\|ref\|YP_648492.1\| nicotinate phosphoribosyltransferase [Yersinia pestis Nepal516], gi\|10... gi\|108778618, gi... - gi\|108806705\|ref\|YP_650621.1\| nicotinate phosphoribosyltransferase [Yersinia pestis Antiqua], gi\|108...	0.0	[1..401]	[6..406]
PNCB_PHOLL - Nicotinate phosphoribosyltransferase OS=Photorhabdus luminescens subsp. laumondii GN=pncB PE=3 SV=1 PNCB_PHOLL - Nicotinate phosphoribosyltransferase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 ...	0.0	[1..400]	[1..403]
gi\|94417530, gi\|... - gi\|94417530\|ref\|ZP_01297348.1\| hypothetical protein PaerP_01000847 [Pseudomonas aeruginosa PA7], gi\|...	0.0	[4..395]	[6..398]
gi\|77636025 - gi\|77636025\|ref\|ZP_00798103.1\| COG1488: Nicotinic acid phosphoribosyltransferase [Yersinia pestis An...	0.0	[1..401]	[6..406]
gi\|60594388, gi\|... - gi\|60594391\|pdb\|1YIR\|D Chain D, Crystal Structure Of A Nicotinate Phosphoribosyltransferase, gi\|6059...	0.0	[4..396]	[8..401]
gi\|84317541 - gi\|84317541\|ref\|ZP_00965981.1\| COG1488: Nicotinic acid phosphoribosyltransferase [Pseudomonas aerugi...	0.0	[4..395]	[8..400]
PNCB_PSE14 - Nicotinate phosphoribosyltransferase OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race...	0.0	[4..395]	[6..398]
gi\|77979212 - gi\|77979212\|ref\|ZP_00834632.1\| COG1488: Nicotinic acid phosphoribosyltransferase [Yersinia intermedi...	0.0	[1..401]	[6..406]

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Predicted Domain #1

Region A:
Residues: [1-401]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQDASPILT SLLDTDAYKL HMQQAVFHHY RHITVAAEFR CRSDELLGVY ADEIRHQVTL  60
   61 MGQLALTSDE FIYLSSLPFF QDDYLHWLRD FRFKPEQVSV AVHDGKLDIR IAGLWCEVIM 120
  121 WEVPLLAVIS EIVHRRRSTQ VTTDQAVQQL RTKLEQFNAL SADIDITHFK LMDFGTRRRF 180
  181 SREIQHTVVS TLKDEFPYLV GTSNYDLART LALAPVGTQA HEWFQAHQQI SPTLANSQRV 240
  241 ALQVWLDEYP NQLGIALTDC ITMDAFLRDF DLAFANRYQG LRHDSGDPIE WGEKAIAHYE 300
  301 KLGIDPMKKV LVFSDNLDLE KALFLYRHFY QRIKLVFGIG TRLTCDIPDV KPLNIVIKLV 360
  361 ECNDKPVAKL SDSPGKTICQ DPAFVDQLRK AFALPLVKKA S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	131.0
Match:	1yirA
Description:	Crystal Structure of a Nicotinate Phosphoribosyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinate phosphoribosyltransferase activity	5.75487746784842	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	4.79136593406808	bayes_pls_golite062009
nicotinate-nucleotide diphosphorylase (carboxylating) activity	3.97201856258863	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	3.41342374351311	bayes_pls_golite062009
catalytic activity	2.59603106157451	bayes_pls_golite062009
transferase activity	1.91642626258277	bayes_pls_golite062009
binding	1.73051405037757	bayes_pls_golite062009
protein binding	0.294646489785198	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: