YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|242376261, gi...
Organism:	Escherichia coli BL21
Length:	550 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|242376261, gi....

Description	E-value	Query Range	Subject Range
gi\|26246495, gi\|... - gi\|26246495\|ref\|NP_752534.1\| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor ...	477.0	[0..1]	[550..1]
gi\|192959147, gi... - gi\|75239024\|ref\|ZP_00723006.1\| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...	476.0	[0..1]	[550..1]
gi\|194412943, gi... - gi\|75209764\|ref\|ZP_00709966.1\| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e... gi\|209910955, gi... - gi\|209917696\|ref\|YP_002291780.1\| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precur... gi\|218359814, gi... - gi\|218553046\|ref\|YP_002385959.1\| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precur... gi\|218350674, gi... - gi\|218693942\|ref\|YP_002401609.1\| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precur... gi\|75257875, gi\|... - gi\|75257875\|ref\|ZP_00729353.1\| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...	476.0	[0..1]	[550..1]
gi\|157160007, gi... - gi\|75194700\|ref\|ZP_00704770.1\| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...	475.0	[0..1]	[550..1]
gi\|110640741, gi... - gi\|110640741\|ref\|YP_668469.1\| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor... gi\|191173684, gi... - gi\|75238232\|ref\|ZP_00722233.1\| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...	475.0	[0..1]	[550..1]
gi\|190902470, gi... - gi\|75229359\|ref\|ZP_00715914.1\| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...	475.0	[0..1]	[550..1]
gi\|82542974, gi\|... - gi\|82542974\|ref\|YP_406921.1\| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor ...	475.0	[0..1]	[550..1]
gi\|15829787, gi\|... - gi\|15829787\|ref\|NP_308560.1\| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor ... gi\|209397585, gi... - gi\|209397585\|ref\|YP_002269131.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. ... gi\|208737316, gi... - gi\|208823123\|ref\|ZP_03263441.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. E... gi\|208816167, gi... - gi\|208816167\|ref\|ZP_03257346.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. E... gi\|208726870, gi... - gi\|208807069\|ref\|ZP_03249406.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. E... gi\|217320999, gi... - gi\|217324778\|ref\|ZP_03440862.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. T... gi\|209778288, gi... - pir\|\|E90695 UDP-sugar diphosphatase (EC 3.6.1.45) precursor [similarity] - Escherichia coli (strain ... gi\|187769672, gi... - gi\|187769672\|gb\|EDU33516.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC419... gi\|189362444, gi... - gi\|189362444\|gb\|EDU80863.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC448... gi\|12513353, gi\|... - gi\|15800209\|ref\|NP_286221.1\| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor ... gi\|168760363, gi... - gi\|189369147\|gb\|EDU87563.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC450... gi\|15829787, gi\|... - gi\|15829787\|ref\|NP_308560.1\| UDP-sugar hydrolase [Escherichia coli O157:H7], gi\|13359990\|dbj\|BAB3395... gi\|168754587, gi... - gi\|189357984\|gb\|EDU76403.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC440... gi\|195936043 - gi\|195936043\|ref\|ZP_03081425.1\| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precurs... gi\|168798046, gi... - gi\|189379298\|gb\|EDU97714.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC508... gi\|168786334, gi... - gi\|189373512\|gb\|EDU91928.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC869... gi\|168778976, gi... - gi\|189003115\|gb\|EDU72101.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC407... gi\|168747842, gi... - gi\|188017625\|gb\|EDU55747.1\| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC411... gi\|254591063, gi... - gi\|254791663\|ref\|YP_003076500.1\| bifunctional UDP-sugar hydrolase and 5'-nucleotidase [Escherichia c...	475.0	[0..1]	[550..1]
gi\|187733948, gi... - gi\|75177573\|ref\|ZP_00697654.1\| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...	474.0	[0..1]	[550..1]
gi\|757842 - gi\|757842\|emb\|CAA27532.1\| UDP-sugar hydrolase [Escherichia coli]	473.0	[0..1]	[550..1]

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Predicted Domain #1

Region A:
Residues: [1-550]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLLQRGVAL ALLTTFTLAS ETALAYEQDK TYKITVLHTN DHHGHFWRNE YGEYGLAAQK  60
   61 TLVDGIRKEV AAEGGSVLLL SGGDINTGVP ESDLQDAEPD FRGMNLVGYD AMAIGNHEFD 120
  121 NPLTVLRQQE KWAKFPLLSA NIYQKSTGER LFKPWALFKR QDLKIAVIGL TTDDTAKIGN 180
  181 PEYFTDIEFR KPADEAKLVI QELQQTEKPD IIIAATHMGH YDNGEHGSNA PGDVEMARAL 240
  241 PAGSLAMIVG GHSQDPVCMA AENKKQVDYV PGTPCKPDQQ NGIWIVQAHE WGKYVGRADF 300
  301 EFRNGEMKMV NYQLIPVNLK KKVTWEDGKS ERVLYTPEIA ENQQMISLLS PFQNKGKAQL 360
  361 EVKIGETNGR LEGDRDKVRF VQTNMGRLIL AAQMDRTGAD FAVMSGGGIR DSIEAGDISY 420
  421 KNVLKVQPFG NVVVYADMTG KEVIDYLTAV AQMKPDSGAY PQFANVSFVA KDGKLNDLKI 480
  481 KGEPVDPAKT YRMATLNFNA TGGDGYPRLD NKPGYVNTGF IDAEVLKAYI QKSSPLDVSV 540
  541 YEPKGEVSWQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	134.0
Match:	1ushA
Description:	5'-NUCLEOTIDASE FROM E. COLI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoprotein phosphatase activity	6.90309911517124	bayes_pls_golite062009
phosphoric ester hydrolase activity	6.76617976580319	bayes_pls_golite062009
phosphatase activity	6.28072946025083	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	5.93537144836081	bayes_pls_golite062009
protein serine/threonine phosphatase activity	5.11265802430394	bayes_pls_golite062009
hydrolase activity	2.06280293513737	bayes_pls_golite062009
catalytic activity	1.39852585255405	bayes_pls_golite062009
binding	0.607014751804583	bayes_pls_golite062009
calcium-dependent protein serine/threonine phosphatase activity	0.598330833036731	bayes_pls_golite062009
protein kinase activity	0.55395641922978	bayes_pls_golite062009
signal transducer activity	0.541715460439478	bayes_pls_golite062009
molecular transducer activity	0.541715460439478	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.395006104431866	bayes_pls_golite062009
kinase activity	0.366390322110727	bayes_pls_golite062009
protein binding	0.184079020957384	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.39246790349923E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: