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View Structure Prediction Details

Protein: gi|18377498, gi|...
Organism: Arabidopsis thaliana
Length: 281 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|18377498, gi|....

Description E-value Query
Range
Subject
Range
gi|3738333, gi|1... - gi|3738333|gb|AAC63674.1| putative chloroplast initiation factor 3 [Arabidopsis thaliana], pir||B846...
281.0 [0..1] [264..1]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGITSTVGF NAILAGATKT VSHPVKSKLF GLRLCVPEFS IVSLSPYHHR RCPAITCRYG  60
   61 GGGGGGSRFP GDRRGRQKES E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.481 d.52.1 Alpha-lytic protease prodomain
View Download 0.439 d.58.17 Metal-binding domain
View Download 0.431 d.52.1 Alpha-lytic protease prodomain
View Download 0.426 d.68.3 SirA-like
View Download 0.396 d.93.1 SH2 domain

Predicted Domain #2
Region A:
Residues: [82-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDSLDISAI RSATVRLIDD QQNMIGLVSK EEAVRRAEDA ELDLVILSPD ADPPVVRMMD  60
   61 YSKYRYEQQK RKKEQQK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.0
Match: 1tifA
Description: TRANSLATION INITIATION FACTOR 3 N-TERMINAL DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation initiation factor activity 5.47485713101079 bayes_pls_golite062009
translation regulator activity 1.62528736558737 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.60662288414996 bayes_pls_golite062009
binding 1.47561914415547 bayes_pls_golite062009
nucleic acid binding 1.12320467511263 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [159-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTTRMDLKEL KMGYNIDQHD YSVRMRAARK FLQDGDKVKV IVNMKGRENE FRNIAIELLR  60
   61 RFQTEIGELG TEESKNFRDR NLFIVLVPNK EVIRKVQEPP PKKKKKPADD KVSAANITAT 120
  121 QDI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.69897
Match: 1tigA
Description: TRANSLATION INITIATION FACTOR 3 C-TERMINAL DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation initiation factor activity 8.09269133854598 bayes_pls_golite062009
translation regulator activity 4.19718241948497 bayes_pls_golite062009
translation factor activity, nucleic acid binding 4.18160226822061 bayes_pls_golite062009
nucleic acid binding 3.21583663075334 bayes_pls_golite062009
binding 2.86350131209009 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle