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View Structure Prediction Details

Protein: gi|220944472, gi...
Organism: synthetic construct
Length: 264 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220944472, gi....

Description E-value Query
Range
Subject
Range
gi|195379390, gi... - gi|27374358|gb|AAO01098.1| CG10754-PA [Drosophila virilis], gi|195379390|ref|XP_002048462.1| GJ13983...
471.0 [0..1] [260..1]
gi|54640988, gi|... - gi|54640988|gb|EAL29739.1| GA10545 [Drosophila pseudoobscura pseudoobscura], gi|125979941|ref|XP_001...
gi|195166735, gi... - gi|195166735|ref|XP_002024190.1| GL22896 [Drosophila persimilis], gi|194107545|gb|EDW29588.1| GL2289...
gi|54640988|gb|E... - GA10545-PA [Drosophila pseudoobscura], GA10545 [Drosophila pseudoobscura pseudoobscura]
468.0 [0..1] [260..1]
gi|58377872, gi|... - gi|58377872|ref|XP_308101.2| ENSANGP00000003103 [Anopheles gambiae str. PEST], gi|55246193|gb|EAA038...
396.0 [0..1] [252..1]
gi|47228339 - gi|47228339|emb|CAG07734.1| unnamed protein product [Tetraodon nigroviridis]
396.0 [0..1] [231..1]
gi|27371271, gi|... - gi|27371271|gb|AAH41254.1| Sf3a2-prov protein [Xenopus laevis], gi|147900053|ref|NP_001080140.1| spl...
394.0 [0..1] [245..1]
CE28910 - status:Confirmed UniProt:Q19335 protein_id:CAA92593.2
393.0 [0..1] [217..1]
gi|157755629 - gi|157755629|ref|XP_001670158.1| Hypothetical protein CBG06223 [Caenorhabditis briggsae AF16]
gi|39593883, gi|... - gi|39593883|emb|CAE62176.1| Hypothetical protein CBG06223 [Caenorhabditis briggsae], gi|187034361|em...
392.0 [0..1] [217..1]
gi|40743500, gi|... - gi|67538720|ref|XP_663134.1| hypothetical protein AN5530.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
389.0 [0..1] [239..1]
gi|118344168, gi... - gi|92081492|dbj|BAE93293.1| zinc finger protein [Ciona intestinalis], gi|118344168|ref|NP_001071907....
389.0 [0..1] [224..1]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFQNRAGGK TGSGGVASWS ETNRDRKERL RQLALETIDL NKDPYFMKNH LGSYECKLCL  60
   61 TLHNNEGSYL AHTQGKKHQD NLARRAAKEA KEAPSSLLAP EKPRVEPKKF VKIGRPGYRV 120
  121 TKQRELSNGQ QSLLFQVDY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.1
Match: 1zr9A
Description: Solution Structure of a Human C2H2-type Zinc Finger Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.37529385176635 bayes_pls_golite062009
DNA binding 3.3049326844117 bayes_pls_golite062009
nucleic acid binding 3.24981360535232 bayes_pls_golite062009
snRNA binding 3.16782731106334 bayes_pls_golite062009
RNA binding 3.11293528368816 bayes_pls_golite062009
U1 snRNA binding 2.86343975521155 bayes_pls_golite062009
binding 2.84954567129719 bayes_pls_golite062009
transcription factor activity 2.44389510173662 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.57041104288348 bayes_pls_golite062009
mRNA binding 1.28525296322454 bayes_pls_golite062009
transcription activator activity 1.20323819132961 bayes_pls_golite062009
protein binding 0.975412203442928 bayes_pls_golite062009
sequence-specific DNA binding 0.732558534458316 bayes_pls_golite062009
transcription repressor activity 0.686318575498149 bayes_pls_golite062009
chromatin binding 0.626365497850853 bayes_pls_golite062009
transcription factor binding 0.515821187939278 bayes_pls_golite062009
cytoskeletal protein binding 0.380243728411498 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.200483461579207 bayes_pls_golite062009
tubulin binding 0.151955152284472 bayes_pls_golite062009
transcription cofactor activity 0.113925660147477 bayes_pls_golite062009
structure-specific DNA binding 0.0855506955761403 bayes_pls_golite062009
microtubule binding 0.05082413668213 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [140-264]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEITESIVPR HRFMSAYEQK IEPPDRKWQY LLFAAEPYET IGFKVPSREV EKSEGKFWTH  60
   61 WNRDTKQFFL QFAFKFEPKI LPPPPPNLHR ALGPPGGFPM PGPPRPAMHP MFNGVHPPPP 120
  121 MLSNN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle