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View Structure Prediction Details

Protein: gi|220954770, gi...
Organism: synthetic construct
Length: 563 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220954770, gi....

Description E-value Query
Range
Subject
Range
gi|114572164 - gi|114572164|ref|XP_514150.2| PREDICTED: ligatin [Pan troglodytes]
574.0 [0..1] [560..100]

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Predicted Domain #1
Region A:
Residues: [1-189]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLKPYRPKS SAALKGSDSK KFRQRVEAAF PHVSVDQLVP AKAAVTQVKI LTHGGVQSMV  60
   61 YCVDKLPLFF ELDGGQLVPT LYTLWIVPDI LPYFTTHEGV LPKLTNGADL MLPGVVPLGV 120
  121 GLSMYGHFKK GQLMAVNLTN NKSAVGVGQL ARSSDELYMC GGHGVAIKML HLFGDKLWSH 180
  181 EPSLVQQIP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.69897
Match: 2ausC
Description: No description for 2ausC was found.

Predicted Domain #2
Region A:
Residues: [190-305]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVKTKALSGE DFPALGSETE RRKTASPATP APVTFATVAQ TEELETETAA LTLESQEAPE  60
   61 SDEEAVEEAS PELILKNAFL SALKNHGKKL PLPLLTSNFY RLYVVTEATE QIDLKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [306-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRYKKLSNFL AEMVDQGFIV VREESKGVDK ITSVDLEHPE VVNFITDVKA SEANGAASET  60
   61 PLFHSELKEM YIVTDVTAAF FTKLNYKRGE GIPAGQIKKI VREYVSKHGL LHPLTKLVRP 120
  121 DDTLIELYGN REVSLSEMCS LITSKMEHSY QMCS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 1v32A
Description: Solution structure of the SWIB/MDM2 domain of the hypothetical protein At5g08430 from Arabidopsis thaliana
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural molecule activity 4.76083886363836 bayes_pls_golite062009
transcription regulator activity 1.93337598023804 bayes_pls_golite062009
binding 1.65769778151884 bayes_pls_golite062009
protein binding 1.3501672529352 bayes_pls_golite062009
basal transcription repressor activity 0.955353508790079 bayes_pls_golite062009
transcription repressor activity 0.6943850197604 bayes_pls_golite062009
transcription activator activity 0.51230769371834 bayes_pls_golite062009
transcription factor binding 0.39586576704049 bayes_pls_golite062009
transcription cofactor activity 0.35852024786909 bayes_pls_golite062009
transcription coactivator activity 0.31113344049068 bayes_pls_golite062009
catalytic activity 0.121624777548864 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [460-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKDTSGKPLI QMSLATRSGN KKVTLVSNIE AYGIILAEFI KLCKQGAAAS TSVVKLPHQK  60
   61 HEQLQIQGNQ VRFVHTLLTE TYKVPPKCIL GLELAKDGKK NKKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.221849
Match: 2if1A
Description: HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation initiation factor activity 6.56930940751046 bayes_pls_golite062009
translation regulator activity 2.27579767245564 bayes_pls_golite062009
translation factor activity, nucleic acid binding 2.25914933413253 bayes_pls_golite062009
nucleic acid binding 1.69119554284364 bayes_pls_golite062009
binding 1.40632629011845 bayes_pls_golite062009
protein binding 0.189517592830504 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle