YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|208967196
Organism:	synthetic construct
Length:	479 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|208967196.

Description	E-value	Query Range	Subject Range
gi\|109102768 - gi\|109102768\|ref\|XP_001111662.1\| PREDICTED: protein phosphatase 1B isoform 6 [Macaca mulatta]	0.0	[1..479]	[1..479]
gi\|73969491 - gi\|73969491\|ref\|XP_851683.1\| PREDICTED: similar to Protein phosphatase 2C beta isoform (PP2C-beta) i...	0.0	[1..479]	[1..479]
PPM1B_BOVIN - Protein phosphatase 1B OS=Bos taurus GN=PPM1B PE=2 SV=2	0.0	[1..479]	[1..484]
gi\|38303831, gi\|... - gi\|38303831\|gb\|AAH61986.1\| Ppm1b protein [Rattus norvegicus], gi\|149050512\|gb\|EDM02685.1\| protein ph...	0.0	[1..467]	[1..465]
gi\|17391324, gi\|... - gi\|94403183\|ref\|XP_990021.1\| PREDICTED: similar to Protein phosphatase 2C isoform beta (PP2C-beta) i...	0.0	[1..479]	[1..477]
gi\|148237920, gi... - gi\|47940266\|gb\|AAH72171.1\| MGC80245 protein [Xenopus laevis], gi\|148237920\|ref\|NP_001085063.1\| ppm1b...	0.0	[1..446]	[1..446]

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Predicted Domain #1

Region A:
Residues: [1-380]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAFLDKPKT EKHNAHGAGN GLRYGLSSMQ GWRVEMEDAH TAVVGIPHGL EDWSFFAVYD  60
   61 GHAGSRVANY CSTHLLEHIT TNEDFRAAGK SGSALELSVE NVKNGIRTGF LKIDEYMRNF 120
  121 SDLRNGMDRS GSTAVGVMIS PKHIYFINCG DSRAVLYRNG QVCFSTQDHK PCNPREKERI 180
  181 QNAGGSVMIQ RVNGSLAVSR ALGDYDYKCV DGKGPTEQLV SPEPEVYEIL RAEEDEFIIL 240
  241 ACDGIWDVMS NEELCEYVKS RLEVSDDLEN VCNWVVDTCL HKGSRDNMSI VLVCFSNAPK 300
  301 VSDEAVKKDS ELDKHLESRV EEIMEKSGEE GMPDLAHVMR ILSAENIPNL PPGGGLAGKR 360
  361 NVIEAVYSRL NPHRESDGAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	113.0
Match:	1a6qA
Description:	CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoprotein phosphatase activity	7.29765002420868	bayes_pls_golite062009
phosphatase activity	6.46633224572308	bayes_pls_golite062009
phosphoric ester hydrolase activity	6.25564034681743	bayes_pls_golite062009
protein serine/threonine phosphatase activity	6.20846750257603	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	5.62997267604309	bayes_pls_golite062009
hydrolase activity	2.93014592649821	bayes_pls_golite062009
binding	1.74689317666387	bayes_pls_golite062009
signal transducer activity	1.61688496161233	bayes_pls_golite062009
molecular transducer activity	1.61688496161233	bayes_pls_golite062009
catalytic activity	1.53401212718168	bayes_pls_golite062009
protein binding	1.47578617076714	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [381-479]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEAEESGSQG KLVEALRQMR INHRGNYRQL LEEMLTSYRL AKVEGEESPA EPAATATSSN  60
   61 SDAGNPVTMQ ESHTESESGL AELDSSNEDA GTKMSGEKI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: