YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|168818214, gi...
Organism:	Salmonella enterica subsp. enterica serovar Weltevreden str. HI_N05-537
Length:	361 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168818214, gi....

Description	E-value	Query Range	Subject Range
gi\|76366002 - gi\|76366002\|gb\|ABA42227.1\| RmlB [Escherichia coli] gi\|191167723, gi... - gi\|191167723\|ref\|ZP_03029531.1\| dTDP-glucose 4,6-dehydratase [Escherichia coli B7A], gi\|190902236\|gb...	0.0	[1..361]	[1..361]
gi\|9957845 - gi\|9957845\|gb\|AAG09522.1\|AF279621_1 dTDP-D-glucose-4,6-dehydratase [Salmonella enterica]	0.0	[1..361]	[1..361]
RMLB_SALTY, RFBB... - dTDP-glucose 4,6-dehydratase OS=Salmonella typhimurium GN=rfbB PE=1 SV=1, dTDP-glucose 4,6-dehydrata... gi\|194443120, gi... - gi\|194443120\|ref\|YP_002041367.1\| dTDP-glucose 4,6-dehydratase [Salmonella enterica subsp. enterica s... gi\|581654, gi\|13... - gi\|581654\|emb\|CAA40115.1\| dTDP-glucose 4,6-dehydratase [Salmonella enterica], gi\|13786958\|pdb\|1G1A\|D... gi\|168466245, gi... - gi\|195631509\|gb\|EDX50069.1\| dTDP-glucose 4,6-dehydratase [Salmonella enterica subsp. enterica serova... gi\|18655662, gi\|... - gi\|18655664\|pdb\|1KEW\|B Chain B, The Crystal Structure Of Dtdp-D-Glucose 4,6-Dehydratase (Rmlb) From ... gi\|194407940, gi... - gi\|194449636\|ref\|YP_002046147.1\| dTDP-glucose 4,6 dehydratase [Salmonella enterica subsp. enterica s... gi\|205338665, gi... - gi\|205338665\|gb\|EDZ25429.1\| dTDP-glucose 4,6-dehydratase [Salmonella enterica subsp. enterica serova... gi\|205330442, gi... - gi\|205330442\|gb\|EDZ17206.1\| dTDP-glucose 4,6-dehydratase [Salmonella enterica subsp. enterica serova... RFBB_SALTY - dTDP-glucose 4,6-dehydratase OS=Salmonella typhimurium GN=rfbB PE=1 SV=1 lcl\|NC_016856.1_... - [gene=rfbB] [protein=dTDP-glucose-4,6-dehydratase] [protein_id=YP_005238132.1] [location=complement(... RMLB_SALTY - dTDP-glucose 4,6-dehydratase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=rfbB...	0.0	[1..361]	[1..361]
gi\|115503058 - gi\|115503058\|gb\|ABI98981.1\| RmlB [Escherichia coli] gi\|62955957 - gi\|62955957\|gb\|AAY23333.1\| RmlB [Shigella boydii]	0.0	[1..361]	[1..361]

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Predicted Domain #1

Region A:
Residues: [1-361]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILITGGAG FIGSAVVRHI IKNTQDTVVN IDKLTYAGNL ESLSDISESN RYNFEHADIC  60
   61 DSAEITRIFE QYQPDAVMHL AAESHVDRSI TGPAAFIETN IVGTYVLLEV ARKYWSALGE 120
  121 DKKNNFRFHH ISTDEVYGDL PHPDEVENSV TLPLFTETTA YAPSSPYSAS KASSDHLVRA 180
  181 WRRTYGLPTI VTNCSNNYGP YHFPEKLIPL VILNALEGKP LPIYGKGDQI RDWLYVEDHA 240
  241 RALHMVVTEG KAGETYNIGG HNEKKNLDVV FTICDLLDEI VPKATSYREQ ITYVADRPGH 300
  301 DRRYAIDAGK ISRELGWKPL ETFESGIRKT VEWYLANTQW VNNVKSGAYQ SWIEQNYEGR 360
  361 Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	107.0
Match:	1g1aA
Description:	dTDP-glucose 4,6-dehydratase (RmlB)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
UDP-glucose 4-epimerase activity	2.13934644118967	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
steroid dehydrogenase activity	1.75109362865449	bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.55012034958204	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.03956654822048	bayes_pls_golite062009
nucleic acid binding	0.868888700854563	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.82673050487418	bayes_pls_golite062009
DNA binding	0.790382977752475	bayes_pls_golite062009
binding	0.784517759335365	bayes_pls_golite062009
transcription regulator activity	0.613310508772122	bayes_pls_golite062009
transcription factor activity	0.11102650759187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: