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View Structure Prediction Details

Protein: gi|190409690
Organism: Saccharomyces cerevisiae RM11-1a
Length: 405 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190409690.

Description E-value Query
Range
Subject
Range
DBR1 - RNA lariat debranching enzyme, involved in intron turnover; required for efficient Ty1 transposition
DBR1_YEAST - Lariat debranching enzyme OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DBR1 PE=1 SV=1
gi|207343619 - gi|207343619|gb|EDZ71031.1| YKL149Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190409690 - gi|190409690|gb|EDV12955.1| RNA lariat debranching enzyme [Saccharomyces cerevisiae RM11-1a]
0.0 [1..405] [1..405]
gi|19114382 - gi|19114382|ref|NP_593470.1| hypothetical protein SPAC17A5.02c [Schizosaccharomyces pombe 972h-]
dbr1 - RNA lariat debranching enzyme Dbr1
0.0 [3..340] [15..375]
DBR1_SCHPO - Lariat debranching enzyme OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dbr1 PE=3 SV=2
dbr1 - RNA lariat debranching enzyme Dbr1
0.0 [3..340] [15..375]
ldbr-PB - The gene lariat debranching enzyme is referred to in FlyBase by the symbol Dmel\ldbr (CG7942, FBgn00...
gi|220942980 - gi|220942980|gb|ACL84033.1| ldbr-PA [synthetic construct]
0.0 [4..353] [1..341]
gi|13879368 - gi|13879368|gb|AAH06661.1| Dbr1 protein [Mus musculus]
0.0 [4..340] [1..289]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [4..339] [1..282]
DBR1_ARATH - Lariat debranching enzyme OS=Arabidopsis thaliana GN=DBR1 PE=2 SV=1
0.0 [4..339] [1..282]
gi|18376344, gi|... - gi|32404108|ref|XP_322667.1| hypothetical protein [Neurospora crassa], gi|28917935|gb|EAA27620.1| co...
gi|85082132 - gi|85082132|ref|XP_956856.1| hypothetical protein NCU03409 [Neurospora crassa OR74A]
1.0E-90 [4..263] [13..266]

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Predicted Domain #1
Region A:
Residues: [1-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKLRIAVQG CCHGQLNQIY KEVSRIHAKT PIDLLIILGD FQSIRDGQDF KSIAIPPKYQ  60
   61 RLGDFISYYN NEIEAPVPTI FIGGNHESMR HLMLLPHGGY VAKNIFYMGY SNVIWFKGIR 120
  121 IGSLSGIWKE WDFNKQRPDW NDLENNNWKA NIRNLYHVRI SDIAPLFMIK HRIDIMLSHD 180
  181 WPNGVVYHGD TKHLLKLKPF FEQDIKEGKL GSPVTWQLLR DLRPQWWLSA HLHVRFMASI 240
  241 KHNKRSHEPP NKSTSKTKKN 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.05
Match: 1kbpA
Description: Purple acid phosphatase, N-terminal domain; Plant purple acid phosphatase, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 2.53080794424314 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.41348361064083 bayes_pls_golite062009
binding 1.30309680165893 bayes_pls_golite062009
catalytic activity 1.30037658165549 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.768201004870964 bayes_pls_golite062009
protein serine/threonine phosphatase activity 0.634242884531037 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.463083693607652 bayes_pls_golite062009
phosphatase activity 0.325160962990544 bayes_pls_golite062009
protein binding 0.20380491058914 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [261-405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNEIDLDLSS DEDERSGIMN CQEENEYDSK YGETRFLALD KCLPRRRWLE ILEIEPDTSH  60
   61 ASWKDENHRM FWDPEFINNL VICQKNKNLL SNKPFNSVNW IELSQSNREE GRDIDWENYA 120
  121 IPAYTLDIQK DEVRQTKAFI SKFMT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle