YRC Public Data Repository - Protein Structure Prediction

Protein:	DNAJ_SALNS
Organism:	Salmonella enterica subsp. enterica serovar Newport str. SL254
Length:	379 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DNAJ_SALNS.

Description	E-value	Query Range	Subject Range
DNAJ_SALPA - Chaperone protein DnaJ OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=dnaJ PE=3 SV=3 DNAJ_SALPA - Chaperone protein DnaJ OS=Salmonella paratyphi A GN=dnaJ PE=2 SV=3 DNAJ_SALPK - Chaperone protein DnaJ OS=Salmonella paratyphi A (strain AKU_12601) GN=dnaJ PE=3 SV=1	0.0	[1..379]	[1..375]
gi\|188495716, gi... - gi\|75515606\|ref\|ZP_00737763.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|168785065, gi... - gi\|189374927\|gb\|EDU93343.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC869], gi\|1687850... sp\|B7UI60\|DNAJ_ECO27 - Chaperone protein dnaJ OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dnaJ PE=3 SV=1 DNAJ_SHISS - Chaperone protein DnaJ OS=Shigella sonnei (strain Ss046) GN=dnaJ PE=3 SV=1 gi\|168762775, gi... - gi\|189366928\|gb\|EDU85344.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC4501], gi\|168762... gi\|192956076, gi... - gi\|75234578\|ref\|ZP_00718919.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_ECOSM - Chaperone protein DnaJ OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=dnaJ PE=3 SV=1 gi\|193065637, gi... - gi\|75256327\|ref\|ZP_00727999.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|189379547, gi... - gi\|189379547\|gb\|EDU97963.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC508], gi\|1687979... DNAJ_ECO27 - Chaperone protein DnaJ OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dnaJ PE=3 SV=1 DNAJ_ECOSE - Chaperone protein DnaJ OS=Escherichia coli (strain SE11) GN=dnaJ PE=3 SV=1 DNAJ_ECOL6 - Chaperone protein DnaJ OS=Escherichia coli O6 GN=dnaJ PE=2 SV=3 DNAJ_ESCF3 - Chaperone protein DnaJ OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) GN=dn... gi\|217325343, gi... - gi\|217325343\|ref\|ZP_03441427.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. TW14588], gi\|2... DNAJ_ECOUT - Chaperone protein DnaJ OS=Escherichia coli (strain UTI89 / UPEC) GN=dnaJ PE=3 SV=1 gi\|15829269, gi\|... - gi\|15829269\|ref\|NP_308042.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. Sakai], gi\|133594... gi\|75229476, gi\|... - gi\|75229476\|ref\|ZP_00716026.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|75235742, gi\|... - gi\|75235742\|ref\|ZP_00719906.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_ECO24 - Chaperone protein DnaJ OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=dnaJ PE=3 SV=1 DNAJ_ECOHS - Chaperone protein DnaJ OS=Escherichia coli O9:H4 (strain HS) GN=dnaJ PE=3 SV=1 gi\|209747186, gi... - pir\|\|G85481 chaperone with DnaK, heat shock protein [imported] - Escherichia coli (strain O157:H7, s... DNAJ_ECO57 - Chaperone protein DnaJ OS=Escherichia coli O157:H7 GN=dnaJ PE=3 SV=3 DNAJ_ECOL6 - Chaperone protein DnaJ OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=dnaJ PE=3 S... DNAJ_ECO45 - Chaperone protein DnaJ OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=dnaJ PE=3 SV=1 gi\|12512693, gi\|... - gi\|15799695\|ref\|NP_285707.1\| chaperone protein DnaJ [Escherichia coli O157:H7 EDL933], gi\|12512693\|g... DNAJ_ECO8A - Chaperone protein DnaJ OS=Escherichia coli O8 (strain IAI1) GN=dnaJ PE=3 SV=1 DNAJ_ECO55 - Chaperone protein DnaJ OS=Escherichia coli (strain 55989 / EAEC) GN=dnaJ PE=3 SV=1 DNAJ_ECO81 - Chaperone protein DnaJ OS=Escherichia coli O81 (strain ED1a) GN=dnaJ PE=3 SV=1 DNAJ_ECOLU - Chaperone protein DnaJ OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=dnaJ PE=3 SV=1 DNAJ_ECO7I - Chaperone protein DnaJ OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=dnaJ PE=3 SV=1 gi\|227837919, gi... - gi\|227885090\|ref\|ZP_04002895.1\| chaperone protein DnaJ [Escherichia coli 83972], gi\|227837919\|gb\|EEJ... gi\|229560216 - gi\|229560216\|ref\|YP_667956.2\| chaperone protein DnaJ [Escherichia coli 536] gi\|229775981 - gi\|229775981\|ref\|YP_851221.2\| chaperone protein DnaJ [Escherichia coli APEC O1] DNAJ_ECOLC - Chaperone protein DnaJ OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=dnaJ PE=3 SV=1	0.0	[1..379]	[1..376]
DNAJ_SHIBS - Chaperone protein DnaJ OS=Shigella boydii serotype 4 (strain Sb227) GN=dnaJ PE=3 SV=1 DNAJ_SHIB3 - Chaperone protein DnaJ OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=dnaJ PE=3 SV=1	0.0	[1..379]	[1..376]
gi\|89106899, gi\|... - gi\|89106899\|ref\|AP_000679.1\| chaperone Hsp40, co-chaperone with DnaK [Escherichia coli str. K-12 sub... DNAJ_ECODH - Chaperone protein DnaJ OS=Escherichia coli (strain K12 / DH10B) GN=dnaJ PE=3 SV=1 DNAJ_ECOLI - Chaperone protein dnaJ (Heat shock protein J) (HSP40) - Escherichia coli EG10240 - chaperone Hsp40, DnaK co-chaperone / DnaK co-chaperone HSP40; DNA-binding protein; stress-related DN... EG10240 - chaperone Hsp40, DnaK co-chaperone / DnaK co-chaperone HSP40; DNA-binding protein; stress-related DN...	0.0	[1..379]	[1..376]
gi\|83585322, gi\|... - gi\|83585322\|ref\|ZP_00923970.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|254286940, gi... - gi\|254286940\|ref\|YP_003052688.1\| chaperone Hsp40, co-chaperone with DnaK [Escherichia coli BL21(DE3)... gi\|251783579, gi... - gi\|251783579\|ref\|YP_002997883.1\| hypothetical protein B21_00015 [Escherichia coli BL21], gi\|24237585... gi\|253972037, gi... - gi\|254160136\|ref\|YP_003043244.1\| chaperone Hsp40, co-chaperone with DnaK [Escherichia coli B str. RE...	0.0	[1..379]	[1..376]
DNAJ_SHIF8 - Chaperone protein DnaJ OS=Shigella flexneri serotype 5b (strain 8401) GN=dnaJ PE=3 SV=1 gi\|30061585, gi\|... - gi\|30061585\|ref\|NP_835756.1\| chaperone protein DnaJ [Shigella flexneri 2a str. 2457T], gi\|30039827\|g...	0.0	[1..379]	[1..376]
gi\|124530383, gi... - gi\|124530383\|ref\|ZP_01701069.1\| chaperone protein DnaJ [Escherichia coli B], gi\|124499274\|gb\|EAY4676... gi\|110640228, gi... - gi\|110640228\|ref\|YP_667956.1\| chaperone protein DnaJ [Escherichia coli 536], gi\|110341820\|gb\|ABG6805...	0.0	[1..379]	[11..386]
DNAJ_SHIDS - Chaperone protein DnaJ OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=dnaJ PE=3 SV=1	0.0	[1..379]	[1..376]
gi\|194429152, gi... - gi\|75209619\|ref\|ZP_00709837.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom...	0.0	[1..379]	[1..376]
gi\|117622308, gi... - gi\|117622308\|ref\|YP_851221.1\| chaperone protein DnaJ [Escherichia coli APEC O1], gi\|115511432\|gb\|ABI... gi\|226902067, gi... - gi\|237704155\|ref\|ZP_04534636.1\| chaperone with DnaK [Escherichia sp. 3_2_53FAA], gi\|226902067\|gb\|EEH...	0.0	[1..379]	[11..386]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKRDYYEIL GVSKTAEERE IKKAYKRLAM KYHPDRNQGD KEAEAKFKEI KEAYEVLTDA  60
   61 QKRAAYDQYG HAAFEQGGMG GGFGGGFNGG ADFSDIFGDV FGDIFGGGRG RQRAAR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.30103
Match:	1xblA
Description:	NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
unfolded protein binding	3.04403163860617	bayes_pls_golite062009
heat shock protein binding	2.17994194200939	bayes_pls_golite062009
binding	2.03854863870179	bayes_pls_golite062009
chaperone binding	1.61155546076854	bayes_pls_golite062009
protein binding	1.35701123337504	bayes_pls_golite062009
Hsp70 protein binding	0.541755903922701	bayes_pls_golite062009
nucleic acid binding	0.423488346839872	bayes_pls_golite062009
transcription regulator activity	0.146399219759372	bayes_pls_golite062009
catalytic activity	0.106988907594358	bayes_pls_golite062009
DNA binding	0.10307408349439	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [117-221]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GADLRYNMDL TLEEAVRGVT KEIRIPTLEE CDVCHGSGAK AGTQPQTCPT CHGSGQVQMR  60
   61 QGFFAVQQTC PHCQGRGTLI KDPCHKCHGH GRVEKSKTLS VKIPA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.0
Match:	1exkA
Description:	Cysteine-rich domain of the chaperone protein DnaJ.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein disulfide isomerase activity	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	2.23398279564144	bayes_pls_golite062009
binding	2.13705208493215	bayes_pls_golite062009
unfolded protein binding	2.04158808514315	bayes_pls_golite062009
protein binding	1.32690171510656	bayes_pls_golite062009
catalytic activity	0.276917867171685	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [222-379]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVDTGDRIRL AGEGEAGEHG APAGDLYVQV QVKQHPIFER EGNNLYCEVP INFAMAALGG  60
   61 EIEVPTLDGR VMLKVPSETQ TGKLFRMRGK GVKSVRGGAQ GDLLCRVVVE TPVGLSEKQK 120
  121 QLLKDLQESF GGPTGEKNSP RSKSFFDGVK KFFDDLTR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.69897
Match:	1xaoA
Description:	Hsp40-Ydj1 dimerization domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: