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View Structure Prediction Details

Protein: gi|157928988, gi...
Organism: synthetic construct
Length: 461 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|157928988, gi....

Description E-value Query
Range
Subject
Range
gi|114602093 - gi|114602093|ref|XP_001157060.1| PREDICTED: similar to SIL1 protein [Pan troglodytes]
4.0E-83 [2..461] [269..728]
gi|109078814, gi... - gi|109078816|ref|XP_001114098.1| PREDICTED: similar to SIL1 protein precursor isoform 3 [Macaca mula...
1.0E-82 [1..461] [1..461]
gi|22760180 - gi|22760180|dbj|BAC11096.1| unnamed protein product [Homo sapiens]
1.0E-78 [1..461] [1..461]
SIL1_RAT - Nucleotide exchange factor SIL1 OS=Rattus norvegicus GN=Sil1 PE=2 SV=1
4.0E-77 [1..461] [1..465]
SIL1_MOUSE - Nucleotide exchange factor SIL1 OS=Mus musculus GN=Sil1 PE=1 SV=2
1.0E-71 [1..461] [1..465]
gi|73971508 - gi|73971508|ref|XP_531925.2| PREDICTED: similar to endoplasmic reticulum chaperone SIL1, homolog of ...
4.0E-71 [1..461] [1..475]
SIL1_BOVIN - Nucleotide exchange factor SIL1 OS=Bos taurus GN=SIL1 PE=2 SV=1
9.0E-69 [1..461] [1..462]

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Predicted Domain #1
Region A:
Residues: [1-461]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPQSLPSSR MAPLGMLLGL LMAACFTFCL SHQNLKEFAL TNPEKSSTKE TERKETKAEE  60
   61 ELDAEVLEVF HPTHEWQALQ PGQAVPAGSH VRLNLQTGER EAKLQYEDKF RNNLKGKRLD 120
  121 INTNTYTSQD LKSALAKFKE GAEMESSKED KARQAEVKRL FRPIEELKKD FDELNVVIET 180
  181 DMQIMVRLIN KFNSSSSSLE EKIAALFDLE YYVHQMDNAQ DLLSFGGLQV VINGLNSTEP 240
  241 LVKEYAAFVL GAAFSSNPKV QVEAIEGGAL QKLLVILATE QPLTAKKKVL FALCSLLRHF 300
  301 PYAQRQFLKL GGLQVLRTLV QEKGTEVLAV RVVTLLYDLV TEKMFAEEEA ELTQEMSPEK 360
  361 LQQYRQVHLL PGLWEQGWCE ITAHLLALPE HDAREKVLQT LGVLLTTCRD RYRQDPQLGR 420
  421 TLASLQAEYQ VLASLELQDG EDEGYFQELL GSVNSLLKEL R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.0
Match: 1wa5B
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.04462323043166 bayes_pls_golite062009
protein binding 1.04044934052933 bayes_pls_golite062009
nucleic acid binding 0.549076739943715 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle