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View Structure Prediction Details

Protein: TWIH_ARATH
Organism: Arabidopsis thaliana
Length: 709 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TWIH_ARATH.

Description E-value Query
Range
Subject
Range
gi|27311757 - gi|27311757|gb|AAO00844.1| Unknown protein [Arabidopsis thaliana]
384.0 [0..1] [709..1]

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Predicted Domain #1
Region A:
Residues: [1-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFLLRLPQI HFRKLSCSMS VLMGSKQFLE FCLLPSFASY PSSPSYSSSR QVSSVSRRFR  60
   61 PVLASRPVSK NSPYYQRTNG LSSYNSIPRV PTPVDTEVEA DKRVVLSRLV TLRRKLAEQG 120
  121 VDAENCPPGQ HSGLICPTCE GGNSGEKSLS LFIAPDGSSA TWNCFRGKCG LKGGVRADGG 180
  181 LASADPIEKV ERKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.09691
Match: 2au3A
Description: Crystal Structure of the Aquifex aeolicus primase (Zinc Binding and RNA Polymerase Domains)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [195-709]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVEGIELEPL CDEIQDYFAA RAISRKTLER NRVMQKRIGD EIVIAFTYWQ RGELVSCKYR  60
   61 SLTKMFFQER KTRRILYGLD DIEKTSEVII VEGEIDKLAM EEAGFLNCVS VPDGAPAKVS 120
  121 SKEIPSEDKD TKYKFLWNCN DYLKKASRIV IATDGDGPGQ AMAEEIARRL GKERCWRVKW 180
  181 PKKSEDEHFK DANEVLMSKG PHLLKEAILD AEPYPILGLF SFKDFFDEID AYYDRTHGHE 240
  241 YGVSTGWKNL DNLYSVVPGE LTVVTGIPNS GKSEWIDAML CNLNHSVGWK FALCSMENKV 300
  301 RDHARKLLEK HIKKPFFDAD YGRSVQRMSV EEKDEGKKWL NDTFYPIRCE MDSLPSIDWV 360
  361 LERAKAAVLR YGIRGLVIDP YNELDHQRTP RQTETEYVSQ MLTKIKRFSQ HHSCHVWFVA 420
  421 HPKQLQHWDG GAPNLYDISG SAHFINKCDN GIIVHRNRDE NAGPLDLVQI GVRKVRNKVA 480
  481 GQIGDAYLCY DRTTGSYSDS PVTPGMPERR SPKRY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.30103
Match: 1q57A
Description: The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.869619296732501 bayes_pls_golite062009
transferase activity 0.17715040725444 bayes_pls_golite062009
hydrolase activity 0.0582794297634999 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0480892970909803 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle