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View Structure Prediction Details

Protein: gi|9955015, gi|9...
Organism: Homo sapiens
Length: 197 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|9955015, gi|9....

Description E-value Query
Range
Subject
Range
PRDX2_CRIGR - Peroxiredoxin-2 OS=Cricetulus griseus GN=PRDX2 PE=2 SV=3
252.0 [0..2] [197..3]
gi|60654143 - gi|60654143|gb|AAX29764.1| peroxiredoxin 2 [synthetic construct]
251.0 [0..2] [197..3]
gi|60818622, gi|... - gi|61362999|gb|AAX42317.1| peroxiredoxin 2 [synthetic construct], gi|60818622|gb|AAX36471.1| peroxir...
PRDX2_MACFA - Peroxiredoxin-2 OS=Macaca fascicularis GN=PRDX2 PE=2 SV=3
gi|114675617 - gi|114675617|ref|XP_524127.2| PREDICTED: peroxiredoxin 2 [Pan troglodytes]
gi|109123563, gi... - gi|109123563|ref|XP_001109216.1| PREDICTED: peroxiredoxin 2 isoform 5 [Macaca mulatta], gi|109123561...
PRDX2 - peroxiredoxin 2
251.0 [0..2] [197..3]
gi|51980440 - gb|AAH82149.1| Unknown (protein for MGC:98395) [Xenopus laevis]
PRDX2_MOUSE - Peroxiredoxin-2 OS=Mus musculus GN=Prdx2 PE=1 SV=3
251.0 [0..2] [197..3]
gi|149037815, gi... - gi|34849738|gb|AAH58481.1| Peroxiredoxin 2 [Rattus norvegicus], gi|149037815|gb|EDL92175.1| rCG51106...
251.0 [0..2] [197..3]

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Predicted Domain #1
Region A:
Residues: [1-197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 XSGNARIGKP APDFKATAVV DGAFKEVKLS DYKGKYVVLF FYPLDFTFVX PTEIIAFSNR  60
   61 AEDFRKLGCE VLGVSVDSQF THLAWINTPR KEGGLGPLNI PLLADVTRRL SEDYGVLKTD 120
  121 EGIAYRGLFI IDGKGVLRQI TVNDLPVGRS VDEALRLVQA FQYTDEHGEV CPAGWKPGSD 180
  181 TIKPNVDDSK EYFSKHN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.0
Match: 1qmvA
Description: Thioredoxin peroxidase 2 (thioredoxin peroxidase B, 2-cys peroxiredoxin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alkyl hydroperoxide reductase activity 4.29610283853788 bayes_pls_golite062009
antioxidant activity 3.8464796631544 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
selenium binding 2.92496040718744 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
transcription regulator activity 2.30799114442278 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.23310780102446 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
protein disulfide oxidoreductase activity 1.47769936616412 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
transferase activity 1.26687471229876 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
protein binding 1.18479617596618 bayes_pls_golite062009
molecular transducer activity 1.11518182894524 bayes_pls_golite062009
signal transducer activity 1.11518182894524 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
peptide binding 0.374493676068876 bayes_pls_golite062009
0.359224524631956 bayes_pls_golite062009
NADH dehydrogenase activity 0.23291471505999 bayes_pls_golite062009
copper ion binding 0.178842772364502 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 0.16328723676608 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 0.0434052164026002 bayes_pls_golite062009

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