From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.747971591384] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
translocon complex | 5.0527E-7 | 2 | 5 | 2 | 6292 |
Sec61 translocon complex | 5.0527E-7 | 2 | 5 | 2 | 6292 |
rough endoplasmic reticulum | 3.3348E-6 | 2 | 12 | 2 | 6292 |
rough endoplasmic reticulum membrane | 3.3348E-6 | 2 | 12 | 2 | 6292 |
endoplasmic reticulum membrane | 4.4352E-4 | 2 | 133 | 2 | 6292 |
endoplasmic reticulum part | 5.6464E-4 | 2 | 150 | 2 | 6292 |
subsynaptic reticulum | 5.6464E-4 | 2 | 150 | 2 | 6292 |
nuclear membrane-endoplasmic reticulum network | 1.3539E-3 | 2 | 232 | 2 | 6292 |
endoplasmic reticulum | 3.3381E-3 | 2 | 364 | 2 | 6292 |
endomembrane system | 3.9918E-3 | 2 | 398 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
cotranslational protein targeting to membrane | 1.3945E-5 | 2 | 24 | 2 | 6292 |
protein targeting to membrane | 6.6999E-5 | 2 | 52 | 2 | 6292 |
protein targeting | 1.3892E-3 | 2 | 235 | 2 | 6292 |
intracellular protein transport | 1.6363E-3 | 2 | 255 | 2 | 6292 |
protein transport | 1.8213E-3 | 2 | 269 | 2 | 6292 |
establishment of protein localization | 1.8485E-3 | 2 | 271 | 2 | 6292 |
cellular protein localization | 1.8898E-3 | 2 | 274 | 2 | 6292 |
cellular macromolecule localization | 2.0305E-3 | 2 | 284 | 2 | 6292 |
protein localization | 2.3118E-3 | 2 | 303 | 2 | 6292 |
macromolecule localization | 3.9717E-3 | 2 | 397 | 2 | 6292 |
intracellular transport | 7.7118E-3 | 2 | 553 | 2 | 6292 |
establishment of localization in cell | 9.0494E-3 | 2 | 599 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
protein transporter activity | 8.3521E-5 | 2 | 58 | 2 | 6292 |
ARF guanyl-nucleotide exchange factor activity | 1.9064E-3 | 2 | 6 | 1 | 6292 |
substrate-specific transporter activity | 2.8436E-3 | 2 | 336 | 2 | 6292 |
transporter activity | 4.1132E-3 | 2 | 404 | 2 | 6292 |