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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.083] [SVM Score: 0.789797489678]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SCC2
  • nuclear cohesin complex
    		•
  • mitotic sister chromatid cohesion
  • double-strand break repair via homologous recombination
    		•
  • molecular_function
    		•
    SMC1
  • nuclear cohesin complex
    		•
  • mitotic sister chromatid cohesion
  • mitotic sister chromatid segregation
  • double-strand break repair
    		•
  • ATPase activity
  • double-stranded DNA binding
  • DNA secondary structure binding
  • AT DNA binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear cohesin complex 7.579E-7 2 6 2 6292
    cohesin complex 7.579E-7 2 6 2 6292
    condensed nuclear chromosome 1.8468E-4 2 86 2 6292
    condensed chromosome 2.2085E-4 2 94 2 6292
    nuclear chromosome part 9.0721E-4 2 190 2 6292
    nuclear chromosome 1.3075E-3 2 228 2 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mitotic sister chromatid cohesion 1.2783E-5 2 23 2 6292
    sister chromatid cohesion 2.5061E-5 2 32 2 6292
    double-strand break repair 8.0641E-5 2 57 2 6292
    mitotic sister chromatid segregation 1.0838E-4 2 66 2 6292
    sister chromatid segregation 1.1854E-4 2 69 2 6292
    mitosis 2.7062E-4 2 104 2 6292
    nuclear division 2.8118E-4 2 106 2 6292
    organelle fission 3.1973E-4 2 113 2 6292
    chromosome segregation 4.1068E-4 2 128 2 6292
    M phase of mitotic cell cycle 4.1068E-4 2 128 2 6292
    DNA repair 9.2646E-4 2 192 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    mitotic cell cycle 1.6363E-3 2 255 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    M phase 2.1762E-3 2 294 2 6292
    cell cycle phase 3.5621E-3 2 376 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    response to stress 6.2277E-3 2 497 2 6292
    cell cycle 6.95E-3 2 525 2 6292
    double-strand break repair via homologous recombination 6.9813E-3 2 22 1 6292
    chromosome organization 7.7677E-3 2 555 2 6292
    recombinational repair 8.248E-3 2 26 1 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    AT DNA binding 9.5344E-4 2 3 1 6292
    DNA secondary structure binding 2.859E-3 2 9 1 6292
    double-stranded DNA binding 7.2981E-3 2 23 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle