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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.876727613078]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
OSH6
  • soluble fraction
  • cytoplasm
  • peripheral to membrane of membrane fraction
    		•
  • sterol transport
  • endocytosis
  • exocytosis
  • sterol metabolic process
    		•
  • oxysterol binding
    		•
    OSH7
  • soluble fraction
  • cytoplasm
    		•
  • sterol transport
  • late endosome to vacuole transport
  • endocytosis
  • exocytosis
  • sterol metabolic process
    		•
  • oxysterol binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    soluble fraction 5.2295E-5 2 46 2 6292
    cell fraction 4.1715E-4 2 129 2 6292
    peripheral to membrane of membrane fraction 4.4455E-3 2 14 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    sterol transport 6.8716E-6 2 17 2 6292
    lipid transport 3.3651E-5 2 37 2 6292
    lipid localization 3.744E-5 2 39 2 6292
    sterol metabolic process 4.3504E-5 2 42 2 6292
    steroid metabolic process 4.5626E-5 2 43 2 6292
    exocytosis 5.2295E-5 2 46 2 6292
    secretion by cell 7.2304E-5 2 54 2 6292
    secretion 7.2304E-5 2 54 2 6292
    endocytosis 1.9342E-4 2 88 2 6292
    membrane invagination 2.2085E-4 2 94 2 6292
    membrane organization 9.8542E-4 2 198 2 6292
    cellular membrane organization 9.8542E-4 2 198 2 6292
    alcohol metabolic process 1.2172E-3 2 220 2 6292
    lipid metabolic process 1.4491E-3 2 240 2 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    late endosome to vacuole transport 7.6148E-3 2 24 1 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    sterol binding 1.819E-6 2 9 2 6292
    oxysterol binding 1.819E-6 2 9 2 6292
    steroid binding 1.819E-6 2 9 2 6292
    lipid binding 6.1895E-5 2 50 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle