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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.967970261087]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

Mre11 complex 1.5158E-7 2 3 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

double-strand break repair via break-induced replication 1.819E-6 2 9 2 6292
meiotic DNA double-strand break formation 2.779E-6 2 11 2 6292
double-strand break repair via homologous recombination 1.1672E-5 2 22 2 6292
double-strand break repair via nonhomologous end joining 1.5158E-5 2 25 2 6292
recombinational repair 1.6421E-5 2 26 2 6292
non-recombinational repair 2.8346E-5 2 34 2 6292
nucleic acid phosphodiester bond hydrolysis 5.2295E-5 2 46 2 6292
double-strand break repair 8.0641E-5 2 57 2 6292
meiosis I 1.5567E-4 2 79 2 6292
DNA recombination 3.2544E-4 2 114 2 6292
M phase of meiotic cell cycle 6.427E-4 2 160 2 6292
meiosis 6.427E-4 2 160 2 6292
meiotic cell cycle 6.7534E-4 2 164 2 6292
DNA repair 9.2646E-4 2 192 2 6292
meiotic DNA double-strand break processing 9.5344E-4 2 3 1 6292
response to DNA damage stimulus 1.4011E-3 2 236 2 6292
DNA catabolic process, exonucleolytic 1.5888E-3 2 5 1 6292
DNA double-strand break processing 1.5888E-3 2 5 1 6292
anatomical structure homeostasis 2.0592E-3 2 286 2 6292
telomere organization 2.0592E-3 2 286 2 6292
telomere maintenance 2.0592E-3 2 286 2 6292
cellular response to stress 2.1173E-3 2 290 2 6292
M phase 2.1762E-3 2 294 2 6292
cell cycle phase 3.5621E-3 2 376 2 6292
cellular response to stimulus 3.6193E-3 2 379 2 6292
homeostatic process 4.1951E-3 2 408 2 6292
DNA catabolic process 4.7627E-3 2 15 1 6292
cell cycle process 6.0534E-3 2 490 2 6292
response to stress 6.2277E-3 2 497 2 6292
cell cycle 6.95E-3 2 525 2 6292
regulation of biological quality 7.6561E-3 2 551 2 6292
chromosome organization 7.7677E-3 2 555 2 6292
DNA metabolic process 8.631E-3 2 585 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

telomeric DNA binding 3.3348E-6 2 12 2 6292
sequence-specific DNA binding 6.1895E-5 2 50 2 6292
adenylate kinase activity 1.2712E-3 2 4 1 6292
DNA binding 1.6492E-3 2 256 2 6292
nucleotide kinase activity 1.9064E-3 2 6 1 6292
phosphotransferase activity, phosphate group as acceptor 3.4937E-3 2 11 1 6292
nucleobase, nucleoside, nucleotide kinase activity 3.811E-3 2 12 1 6292
endodeoxyribonuclease activity 6.9813E-3 2 22 1 6292
deoxyribonuclease activity 9.1975E-3 2 29 1 6292
protein binding 9.4468E-3 2 612 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle