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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Sir3. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nuclear heterochromatin 3.3344E-3 3 7 1 6292
heterochromatin 3.3344E-3 3 7 1 6292
nuclear telomeric heterochromatin 3.3344E-3 3 7 1 6292
telomeric heterochromatin 3.3344E-3 3 7 1 6292
proton-transporting V-type ATPase, V1 domain 3.8101E-3 3 8 1 6292
vacuolar proton-transporting V-type ATPase, V1 domain 3.8101E-3 3 8 1 6292
chromatin silencing complex 4.2857E-3 3 9 1 6292
telomere cap complex 5.2364E-3 3 11 1 6292
nuclear telomere cap complex 5.2364E-3 3 11 1 6292
protein complex 5.8881E-3 3 1137 3 6292
proton-transporting two-sector ATPase complex, catalytic domain 6.1865E-3 3 13 1 6292
proton-transporting V-type ATPase complex 7.136E-3 3 15 1 6292
vacuolar proton-transporting V-type ATPase complex 7.136E-3 3 15 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

intron homing 2.8585E-3 3 6 1 6292
loss of chromatin silencing involved in replicative cell aging 4.2857E-3 3 9 1 6292
progressive alteration of chromatin involved in replicative cell aging 4.7611E-3 3 10 1 6292
loss of chromatin silencing 4.7611E-3 3 10 1 6292
progressive alteration of chromatin involved in cell aging 5.2364E-3 3 11 1 6292
positive regulation of gene expression, epigenetic 5.2364E-3 3 11 1 6292
regulation of gene silencing 5.2364E-3 3 11 1 6292
negative regulation of gene silencing 5.2364E-3 3 11 1 6292
regulation of chromatin silencing 5.2364E-3 3 11 1 6292
negative regulation of chromatin silencing 5.2364E-3 3 11 1 6292
protein deubiquitination 9.9809E-3 3 21 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

structural constituent of chromatin 9.5344E-4 3 2 1 6292
proton-transporting ATPase activity, rotational mechanism 6.1865E-3 3 13 1 6292
histone binding 6.6614E-3 3 14 1 6292
cation-transporting ATPase activity 7.6106E-3 3 16 1 6292
ubiquitin-specific protease activity 9.5071E-3 3 20 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle