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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 5 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription factor TFIID complex 3.66E-14 5 15 5 6292
DNA-directed RNA polymerase II, holoenzyme 4.6555E-11 5 56 5 6292
transcription factor complex 1.5869E-10 5 71 5 6292
nucleoplasm part 8.6048E-8 5 245 5 6292
nucleoplasm 1.2538E-7 5 264 5 6292
nuclear lumen 1.895E-6 5 453 5 6292
organelle lumen 1.2528E-5 5 660 5 6292
intracellular organelle lumen 1.2528E-5 5 660 5 6292
membrane-enclosed lumen 1.6827E-5 5 700 5 6292
nuclear part 1.6432E-4 5 1103 5 6292
protein complex 1.913E-4 5 1137 5 6292
macromolecular complex 1.1794E-3 5 1635 5 6292
nucleus 3.5796E-3 5 2041 5 6292
organelle part 6.2578E-3 5 2282 5 6292
intracellular organelle part 6.2578E-3 5 2282 5 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulation of transcription involved in G1 phase of mitotic cell cycle 7.6616E-11 5 14 4 6292
G1 phase of mitotic cell cycle 1.3411E-9 5 27 4 6292
G1 phase 1.3411E-9 5 27 4 6292
transcription initiation from RNA polymerase II promoter 1.3595E-8 5 47 4 6292
transcription initiation 3.2292E-8 5 58 4 6292
interphase of mitotic cell cycle 2.6239E-7 5 97 4 6292
interphase 2.6239E-7 5 97 4 6292
transcription from RNA polymerase II promoter 4.1586E-7 5 335 5 6292
protein complex biogenesis 1.7386E-6 5 155 4 6292
protein complex assembly 1.7386E-6 5 155 4 6292
transcription, DNA-dependent 3.2057E-6 5 503 5 6292
RNA biosynthetic process 3.3689E-6 5 508 5 6292
transcription 5.1116E-6 5 552 5 6292
regulation of transcription from RNA polymerase II promoter 8.1644E-6 5 228 4 6292
mitotic cell cycle 1.2765E-5 5 255 4 6292
macromolecular complex assembly 1.88E-5 5 281 4 6292
macromolecular complex subunit organization 4.8711E-5 5 357 4 6292
regulation of transcription, DNA-dependent 4.9254E-5 5 358 4 6292
regulation of RNA metabolic process 5.2042E-5 5 363 4 6292
cell cycle phase 5.9837E-5 5 376 4 6292
regulation of transcription 6.5047E-5 5 384 4 6292
cellular component assembly 6.5721E-5 5 385 4 6292
RNA metabolic process 7.942E-5 5 954 5 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.8471E-5 5 415 4 6292
regulation of nitrogen compound metabolic process 8.9318E-5 5 416 4 6292
regulation of gene expression 1.1661E-4 5 445 4 6292
regulation of macromolecule biosynthetic process 1.2842E-4 5 456 4 6292
regulation of cellular biosynthetic process 1.4716E-4 5 472 4 6292
regulation of biosynthetic process 1.484E-4 5 473 4 6292
regulation of macromolecule metabolic process 1.6786E-4 5 488 4 6292
cell cycle process 1.7059E-4 5 490 4 6292
regulation of primary metabolic process 2.06E-4 5 514 4 6292
cell cycle 2.2393E-4 5 525 4 6292
cellular macromolecule biosynthetic process 2.3732E-4 5 1187 5 6292
macromolecule biosynthetic process 2.3933E-4 5 1189 5 6292
regulation of cellular metabolic process 2.4298E-4 5 536 4 6292
regulation of metabolic process 2.6322E-4 5 547 4 6292
gene expression 3.5034E-4 5 1283 5 6292
nucleic acid metabolic process 5.7208E-4 5 1415 5 6292
cellular component biogenesis 6.6989E-4 5 694 4 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.5045E-4 5 1566 5 6292
cellular biosynthetic process 9.5349E-4 5 1567 5 6292
biosynthetic process 1.065E-3 5 1602 5 6292
regulation of cellular process 1.1441E-3 5 796 4 6292
regulation of biological process 1.3089E-3 5 824 4 6292
cellular nitrogen compound metabolic process 1.7545E-3 5 1770 5 6292
nitrogen compound metabolic process 1.8612E-3 5 1791 5 6292
biological regulation 5.8209E-3 5 1213 4 6292
cellular macromolecule metabolic process 6.2991E-3 5 2285 5 6292
macromolecule metabolic process 7.2329E-3 5 2349 5 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA polymerase II transcription factor activity 3.4887E-9 5 130 5 6292
general RNA polymerase II transcription factor activity 4.8322E-8 5 64 4 6292
transcription regulator activity 4.4145E-7 5 339 5 6292

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