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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
SPT15
  • nucleus
  • RNA polymerase I transcription factor complex
  • transcription factor TFIID complex
  • transcription factor TFIIIB complex
  • transcription from RNA polymerase III promoter
  • transcription initiation from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
  • transcription initiation from RNA polymerase II promoter
  • DNA binding
  • RNA polymerase I transcription factor activity
  • protein homodimerization activity
  • general RNA polymerase II transcription factor activity
  • DNA bending activity
  • RNA polymerase III transcription factor activity
  • TAF1
  • transcription factor TFIID complex
  • protein amino acid phosphorylation
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • histone acetyltransferase activity
  • general RNA polymerase II transcription factor activity
  • protein serine/threonine kinase activity
  • TAF11
  • transcription factor TFIID complex
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF12
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF3
  • transcription factor TFIID complex
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF4
  • transcription factor TFIID complex
  • transcription from RNA polymerase II promoter
  • RNA polymerase II transcription factor activity
  • TAF9
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    transcription factor TFIID complex 8.335E-20 7 15 7 6292
    DNA-directed RNA polymerase II, holoenzyme 3.004E-15 7 56 7 6292
    transcription factor complex 1.7226E-14 7 71 7 6292
    nucleoplasm part 1.2489E-10 7 245 7 6292
    nucleoplasm 2.1199E-10 7 264 7 6292
    nuclear lumen 9.6025E-9 7 453 7 6292
    organelle lumen 1.3579E-7 7 660 7 6292
    intracellular organelle lumen 1.3579E-7 7 660 7 6292
    membrane-enclosed lumen 2.0537E-7 7 700 7 6292
    nuclear part 5.0081E-6 7 1103 7 6292
    protein complex 6.1975E-6 7 1137 7 6292
    macromolecular complex 7.9244E-5 7 1635 7 6292
    SLIK (SAGA-like) complex 1.2639E-4 7 16 2 6292
    SAGA complex 2.4252E-4 7 22 2 6292
    SAGA-type complex 2.6548E-4 7 23 2 6292
    nucleus 3.7528E-4 7 2041 7 6292
    organelle part 8.2061E-4 7 2282 7 6292
    intracellular organelle part 8.2061E-4 7 2282 7 6292
    histone acetyltransferase complex 9.8164E-4 7 44 2 6292
    transcription factor TFIIIB complex 3.3344E-3 7 3 1 6292
    RNA polymerase I transcription factor complex 9.9746E-3 7 9 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    regulation of transcription involved in G1 phase of mitotic cell cycle 5.1118E-13 7 14 5 6292
    transcription initiation from RNA polymerase II promoter 8.6937E-13 7 47 6 6292
    transcription initiation 3.2722E-12 7 58 6 6292
    G1 phase of mitotic cell cycle 2.0542E-11 7 27 5 6292
    G1 phase 2.0542E-11 7 27 5 6292
    transcription from RNA polymerase II promoter 1.1425E-9 7 335 7 6292
    protein complex biogenesis 1.393E-9 7 155 6 6292
    protein complex assembly 1.393E-9 7 155 6 6292
    interphase of mitotic cell cycle 1.6095E-8 7 97 5 6292
    interphase 1.6095E-8 7 97 5 6292
    transcription, DNA-dependent 2.0077E-8 7 503 7 6292
    RNA biosynthetic process 2.1525E-8 7 508 7 6292
    transcription 3.8629E-8 7 552 7 6292
    macromolecular complex assembly 5.0781E-8 7 281 6 6292
    macromolecular complex subunit organization 2.1368E-7 7 357 6 6292
    cellular component assembly 3.3583E-7 7 385 6 6292
    regulation of transcription from RNA polymerase II promoter 1.1842E-6 7 228 5 6292
    RNA metabolic process 1.8079E-6 7 954 7 6292
    mitotic cell cycle 2.0667E-6 7 255 5 6292
    cellular macromolecule biosynthetic process 8.3828E-6 7 1187 7 6292
    macromolecule biosynthetic process 8.4824E-6 7 1189 7 6292
    regulation of transcription, DNA-dependent 1.1082E-5 7 358 5 6292
    cellular component biogenesis 1.1204E-5 7 694 6 6292
    regulation of RNA metabolic process 1.1866E-5 7 363 5 6292
    cell cycle phase 1.411E-5 7 376 5 6292
    gene expression 1.4468E-5 7 1283 7 6292
    regulation of transcription 1.5651E-5 7 384 5 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.292E-5 7 415 5 6292
    regulation of nitrogen compound metabolic process 2.3192E-5 7 416 5 6292
    nucleic acid metabolic process 2.8759E-5 7 1415 7 6292
    regulation of gene expression 3.2272E-5 7 445 5 6292
    regulation of macromolecule biosynthetic process 3.637E-5 7 456 5 6292
    regulation of cellular biosynthetic process 4.3052E-5 7 472 5 6292
    regulation of biosynthetic process 4.35E-5 7 473 5 6292
    regulation of macromolecule metabolic process 5.0667E-5 7 488 5 6292
    cell cycle process 5.1689E-5 7 490 5 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5.8565E-5 7 1566 7 6292
    cellular biosynthetic process 5.8828E-5 7 1567 7 6292
    regulation of primary metabolic process 6.5267E-5 7 514 5 6292
    biosynthetic process 6.8686E-5 7 1602 7 6292
    cell cycle 7.236E-5 7 525 5 6292
    regulation of cellular metabolic process 8.0046E-5 7 536 5 6292
    regulation of metabolic process 8.836E-5 7 547 5 6292
    cellular nitrogen compound metabolic process 1.3822E-4 7 1770 7 6292
    nitrogen compound metabolic process 1.5014E-4 7 1791 7 6292
    regulation of cellular process 5.3954E-4 7 796 5 6292
    regulation of biological process 6.3633E-4 7 824 5 6292
    histone acetylation 6.5652E-4 7 36 2 6292
    cellular macromolecule metabolic process 8.282E-4 7 2285 7 6292
    macromolecule metabolic process 1.0051E-3 7 2349 7 6292
    protein amino acid acetylation 1.0729E-3 7 46 2 6292
    cellular component organization 1.3786E-3 7 1582 6 6292
    protein amino acid acylation 1.7614E-3 7 59 2 6292
    covalent chromatin modification 3.8803E-3 7 88 2 6292
    histone modification 3.8803E-3 7 88 2 6292
    biological regulation 3.9225E-3 7 1213 5 6292
    primary metabolic process 4.3588E-3 7 2896 7 6292
    post-translational protein modification 5.3413E-3 7 357 3 6292
    cellular metabolic process 6.026E-3 7 3033 7 6292
    metabolic process 7.9792E-3 7 3157 7 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA polymerase II transcription factor activity 1.3683E-12 7 130 7 6292
    general RNA polymerase II transcription factor activity 6.0562E-12 7 64 6 6292
    transcription regulator activity 1.2424E-9 7 339 7 6292
    protein homodimerization activity 2.224E-3 7 2 1 6292
    identical protein binding 3.3344E-3 7 3 1 6292
    protein dimerization activity 6.6592E-3 7 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle