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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ATE1
  • cytoplasm
  • protein modification process
  • protein arginylation
  • arginyltransferase activity
  • CDC28
  • nucleus
  • cytoplasm
  • ribosome
  • G2/M transition of mitotic cell cycle
  • transcription
  • S phase of mitotic cell cycle
  • G1/S transition of mitotic cell cycle
  • regulation of meiosis
  • protein amino acid phosphorylation
  • cyclin-dependent protein kinase activity
  • CKS1
  • nucleus
  • cytoplasm
  • transcription
  • ubiquitin binding
  • protein kinase activator activity
  • CLB2
  • nucleus
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • spindle
  • G2/M transition of mitotic cell cycle
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • CLB3
  • nucleus
  • cytoplasm
  • G2/M transition of mitotic cell cycle
  • S phase of mitotic cell cycle
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • CLB4
  • nucleus
  • cytoplasm
  • spindle pole body
  • G2/M transition of mitotic cell cycle
  • S phase of mitotic cell cycle
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • CLB5
  • nucleus
  • spindle assembly
  • G2/M transition of mitotic cell cycle
  • G1/S transition of mitotic cell cycle
  • positive regulation of DNA replication
  • regulation of S phase of mitotic cell cycle
  • premeiotic DNA synthesis
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • SIC1
  • nucleus
  • cytoplasm
  • G1/S transition of mitotic cell cycle
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase inhibitor activity
  • SKG3
  • cellular bud
  • cytoplasm
  • cellular bud neck
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    microtubule organizing center 3.3951E-3 9 63 2 6292
    spindle pole body 3.3951E-3 9 63 2 6292
    spindle pole 3.9454E-3 9 68 2 6292
    spindle 6.6772E-3 9 89 2 6292
    nucleus 6.9589E-3 9 2041 7 6292
    microtubule cytoskeleton 9.3697E-3 9 106 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    regulation of cyclin-dependent protein kinase activity 3.0598E-12 9 14 5 6292
    regulation of kinase activity 9.9896E-11 9 26 5 6292
    regulation of protein kinase activity 9.9896E-11 9 26 5 6292
    regulation of transferase activity 9.9896E-11 9 26 5 6292
    G2/M transition of mitotic cell cycle 1.8006E-10 9 29 5 6292
    regulation of phosphorylation 2.5735E-10 9 31 5 6292
    S phase 4.0402E-10 9 10 4 6292
    S phase of mitotic cell cycle 4.0402E-10 9 10 4 6292
    regulation of phosphate metabolic process 7.5742E-10 9 38 5 6292
    regulation of phosphorus metabolic process 7.5742E-10 9 38 5 6292
    interphase of mitotic cell cycle 9.3E-10 9 97 6 6292
    interphase 9.3E-10 9 97 6 6292
    regulation of catalytic activity 1.6335E-9 9 44 5 6292
    regulation of molecular function 1.6335E-9 9 44 5 6292
    regulation of cell cycle 5.7993E-9 9 131 6 6292
    phosphorylation 3.818E-8 9 179 6 6292
    phosphorus metabolic process 1.67E-7 9 229 6 6292
    phosphate metabolic process 1.67E-7 9 229 6 6292
    mitotic cell cycle 3.1704E-7 9 255 6 6292
    cell cycle phase 3.1544E-6 9 376 6 6292
    cell cycle process 1.4845E-5 9 490 6 6292
    cell cycle 2.2162E-5 9 525 6 6292
    G1/S transition of mitotic cell cycle 3.8361E-5 9 50 3 6292
    regulation of cellular process 2.4084E-4 9 796 6 6292
    regulation of biological process 2.9278E-4 9 824 6 6292
    regulation of cellular metabolic process 4.1537E-4 9 536 5 6292
    regulation of metabolic process 4.5709E-4 9 547 5 6292
    protein arginylation 1.4304E-3 9 1 1 6292
    spindle assembly 1.4304E-3 9 1 1 6292
    biological regulation 2.4952E-3 9 1213 6 6292
    positive regulation of DNA replication 2.859E-3 9 2 1 6292
    regulation of S phase 4.2857E-3 9 3 1 6292
    regulation of S phase of mitotic cell cycle 4.2857E-3 9 3 1 6292
    positive regulation of DNA metabolic process 4.2857E-3 9 3 1 6292
    regulation of cell cycle process 5.5575E-3 9 81 2 6292
    premeiotic DNA synthesis 7.1338E-3 9 5 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein kinase regulator activity 9.0029E-12 9 46 6 6292
    kinase regulator activity 1.3424E-11 9 49 6 6292
    cyclin-dependent protein kinase regulator activity 9.9896E-11 9 26 5 6292
    enzyme regulator activity 9.1298E-8 9 207 6 6292
    arginyltransferase activity 1.4304E-3 9 1 1 6292
    cyclin-dependent protein kinase inhibitor activity 4.2857E-3 9 3 1 6292
    protein serine/threonine kinase inhibitor activity 5.7106E-3 9 4 1 6292
    transferase activity, transferring amino-acyl groups 7.1338E-3 9 5 1 6292
    ubiquitin binding 9.9746E-3 9 7 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle