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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 390
Complex Size: 5 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mitochondrial pyruvate dehydrogenase complex 7.3127E-17 5 6 5 6292
pyruvate dehydrogenase complex 7.3127E-17 5 6 5 6292
mitochondrial matrix 1.6197E-8 5 176 5 6292
mitochondrial lumen 1.6197E-8 5 176 5 6292
nucleoid 6.2313E-7 5 26 3 6292
mitochondrial nucleoid 6.2313E-7 5 26 3 6292
mitochondrial part 2.4046E-6 5 475 5 6292
organelle lumen 1.2528E-5 5 660 5 6292
intracellular organelle lumen 1.2528E-5 5 660 5 6292
membrane-enclosed lumen 1.6827E-5 5 700 5 6292
mitochondrion 1.814E-4 5 1125 5 6292
protein complex 1.913E-4 5 1137 5 6292
macromolecular complex 1.1794E-3 5 1635 5 6292
mitochondrial oxoglutarate dehydrogenase complex 2.3825E-3 5 3 1 6292
oxoglutarate dehydrogenase complex 2.3825E-3 5 3 1 6292
glycine cleavage complex 4.7604E-3 5 6 1 6292
organelle part 6.2578E-3 5 2282 5 6292
intracellular organelle part 6.2578E-3 5 2282 5 6292
cytoplasmic part 9.5281E-3 5 2482 5 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

pyruvate metabolic process 1.3236E-11 5 44 5 6292
monocarboxylic acid metabolic process 4.069E-9 5 134 5 6292
organic acid metabolic process 4.0352E-7 5 333 5 6292
oxoacid metabolic process 4.0352E-7 5 333 5 6292
carboxylic acid metabolic process 4.0352E-7 5 333 5 6292
cellular ketone metabolic process 4.8924E-7 5 346 5 6292
acetyl-CoA biosynthetic process from pyruvate 5.0527E-7 5 2 2 6292
acetyl-CoA biosynthetic process 3.0297E-6 5 4 2 6292
small molecule metabolic process 2.5415E-5 5 760 5 6292
acetyl-CoA metabolic process 9.5453E-5 5 20 2 6292
coenzyme biosynthetic process 7.3776E-4 5 55 2 6292
valine catabolic process 7.9466E-4 5 1 1 6292
valine metabolic process 7.9466E-4 5 1 1 6292
isoleucine catabolic process 7.9466E-4 5 1 1 6292
cofactor biosynthetic process 1.5574E-3 5 80 2 6292
L-serine metabolic process 1.5888E-3 5 2 1 6292
L-serine biosynthetic process 1.5888E-3 5 2 1 6292
leucine catabolic process 1.5888E-3 5 2 1 6292
isoleucine metabolic process 2.3825E-3 5 3 1 6292
branched chain family amino acid catabolic process 3.1756E-3 5 4 1 6292
coenzyme metabolic process 3.4741E-3 5 120 2 6292
glycine catabolic process 4.7604E-3 5 6 1 6292
cofactor metabolic process 5.67E-3 5 154 2 6292
serine family amino acid catabolic process 6.3431E-3 5 8 1 6292
glycine metabolic process 6.3431E-3 5 8 1 6292
leucine metabolic process 6.3431E-3 5 8 1 6292
serine family amino acid biosynthetic process 9.5026E-3 5 12 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

pyruvate dehydrogenase (acetyl-transferring) activity 9.6371E-10 5 4 3 6292
pyruvate dehydrogenase activity 9.6371E-10 5 4 3 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 2.4087E-9 5 5 3 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors 5.5136E-7 5 25 3 6292
dihydrolipoyllysine-residue acetyltransferase activity 7.9466E-4 5 1 1 6292
dihydrolipoyl dehydrogenase activity 7.9466E-4 5 1 1 6292
dihydrolipoamide S-acyltransferase activity 7.9466E-4 5 1 1 6292
oxidoreductase activity 8.2425E-4 5 281 3 6292
S-acetyltransferase activity 1.5888E-3 5 2 1 6292
oxoglutarate dehydrogenase (succinyl-transferring) activity 1.5888E-3 5 2 1 6292
glycine dehydrogenase (decarboxylating) activity 4.7604E-3 5 6 1 6292
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 4.7604E-3 5 6 1 6292
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 5.552E-3 5 7 1 6292
oxidoreductase activity, acting on the CH-NH2 group of donors 9.5026E-3 5 12 1 6292

YRC Informatics Platform - Version 3.0
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