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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 16 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
OSH7
  • soluble fraction
  • cytoplasm
  • sterol transport
  • late endosome to vacuole transport
  • endocytosis
  • exocytosis
  • sterol metabolic process
  • oxysterol binding
  • RPN10
  • proteasome regulatory particle, base subcomplex
  • proteasome complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • RPN11
  • nucleus
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • RPN12
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • RPN2
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • protein binding, bridging
  • RPN3
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • molecular_function
  • RPN5
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • molecular_function
  • RPN6
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • structural molecule activity
  • RPN7
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • structural molecule activity
  • RPN8
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • molecular_function
  • RPN9
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • structural molecule activity
  • RPT2
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RPT3
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RPT4
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RPT6
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • UBP6
  • proteasome regulatory particle
  • protein deubiquitination
  • ubiquitin-specific protease activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    proteasome accessory complex 1.0864E-38 16 23 15 6292
    proteasome regulatory particle 1.0864E-38 16 23 15 6292
    proteasome complex 2.4133E-32 16 48 15 6292
    proteasome regulatory particle, lid subcomplex 9.5269E-21 16 10 8 6292
    proteasome regulatory particle, base subcomplex 7.7922E-15 16 9 6 6292
    protein complex 8.8311E-11 16 1137 15 6292
    macromolecular complex 1.9232E-8 16 1635 15 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    modification-dependent protein catabolic process 2.1216E-21 16 156 14 6292
    ubiquitin-dependent protein catabolic process 2.1216E-21 16 156 14 6292
    proteolysis involved in cellular protein catabolic process 2.7999E-21 16 159 14 6292
    modification-dependent macromolecule catabolic process 4.3931E-21 16 164 14 6292
    cellular protein catabolic process 8.0613E-21 16 171 14 6292
    proteolysis 3.18E-20 16 188 14 6292
    protein catabolic process 3.4334E-20 16 189 14 6292
    cellular macromolecule catabolic process 4.3964E-18 16 265 14 6292
    macromolecule catabolic process 1.9312E-17 16 294 14 6292
    cellular catabolic process 2.5435E-15 16 415 14 6292
    catabolic process 3.1202E-14 16 496 14 6292
    cellular protein metabolic process 3.7773E-11 16 1074 15 6292
    protein metabolic process 8.7162E-11 16 1136 15 6292
    cellular macromolecule metabolic process 2.5883E-6 16 2285 15 6292
    macromolecule metabolic process 3.8653E-6 16 2349 15 6292
    primary metabolic process 3.9666E-6 16 2896 16 6292
    metabolic process 1.5832E-5 16 3157 16 6292
    cellular metabolic process 1.5217E-4 16 3033 15 6292
    cellular process 3.565E-3 16 4426 16 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    endopeptidase activity 2.0954E-13 16 54 8 6292
    peptidase activity, acting on L-amino acid peptides 2.9102E-13 16 95 9 6292
    peptidase activity 1.8119E-10 16 192 9 6292
    hydrolase activity 1.1792E-4 16 911 9 6292
    ATPase activity 1.6283E-3 16 211 4 6292
    nucleoside-triphosphatase activity 8.0952E-3 16 329 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle