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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.583535189272]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SPT16
  • FACT complex
  • nuclear chromatin
  • alpha DNA polymerase:primase complex
  • transcription elongation factor complex
    		•
  • transcription initiation from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
    		•
  • transcription elongation regulator activity
  • RNA polymerase II transcription elongation factor activity
    		•
    TFB5
  • nucleus
  • holo TFIIH complex
    		•
  • DNA repair
  • nucleotide-excision repair
  • transcription initiation from RNA polymerase II promoter
    		•
  • general RNA polymerase II transcription factor activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    FACT complex 6.3568E-4 2 2 1 6292
    nucleoplasm part 1.5102E-3 2 245 2 6292
    nucleoplasm 1.7541E-3 2 264 2 6292
    alpha DNA polymerase:primase complex 2.224E-3 2 7 1 6292
    holo TFIIH complex 3.1764E-3 2 10 1 6292
    nuclear lumen 5.1728E-3 2 453 2 6292
    nuclear replisome 5.7138E-3 2 18 1 6292
    replisome 5.7138E-3 2 18 1 6292
    nuclear replication fork 6.3477E-3 2 20 1 6292
    transcription elongation factor complex 7.2981E-3 2 23 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription initiation from RNA polymerase II promoter 5.4619E-5 2 47 2 6292
    transcription initiation 8.3521E-5 2 58 2 6292
    protein complex assembly 6.0304E-4 2 155 2 6292
    protein complex biogenesis 6.0304E-4 2 155 2 6292
    macromolecular complex assembly 1.9877E-3 2 281 2 6292
    transcription from RNA polymerase II promoter 2.8267E-3 2 335 2 6292
    macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
    cellular component assembly 3.7349E-3 2 385 2 6292
    transcription, DNA-dependent 6.3792E-3 2 503 2 6292
    RNA biosynthetic process 6.5067E-3 2 508 2 6292
    transcription 7.6839E-3 2 552 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription regulator activity 2.8947E-3 2 339 2 6292
    RNA polymerase II transcription elongation factor activity 4.1283E-3 2 13 1 6292
    transcription elongation regulator activity 6.0308E-3 2 19 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle