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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.611824900679]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nuclear chromosome part 9.0721E-4 2 190 2 6292
DNA replication factor A complex 9.5344E-4 2 3 1 6292
nuclear chromosome 1.3075E-3 2 228 2 6292
chromosomal part 1.413E-3 2 237 2 6292
chromosome 1.8898E-3 2 274 2 6292
EKC/KEOPS protein complex 2.859E-3 2 9 1 6292
nuclear replisome 5.7138E-3 2 18 1 6292
replisome 5.7138E-3 2 18 1 6292
nuclear replication fork 6.3477E-3 2 20 1 6292
chromosome, telomeric region 8.5646E-3 2 27 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication, synthesis of RNA primer 1.5888E-3 2 5 1 6292
positive regulation of transcription by pheromones 2.224E-3 2 7 1 6292
positive regulation of transcription from RNA polymerase II promoter by pheromones 2.224E-3 2 7 1 6292
positive regulation of gene-specific transcription from RNA polymerase II promoter 2.224E-3 2 7 1 6292
gene-specific transcription from RNA polymerase II promoter 3.1764E-3 2 10 1 6292
regulation of transcription by pheromones 3.1764E-3 2 10 1 6292
regulation of transcription from RNA polymerase II promoter by pheromones 3.1764E-3 2 10 1 6292
cellular response to pheromone 3.1764E-3 2 10 1 6292
mating projection assembly 3.1764E-3 2 10 1 6292
regulation of gene-specific transcription from RNA polymerase II promoter 3.1764E-3 2 10 1 6292
cell projection assembly 3.4937E-3 2 11 1 6292
cell projection organization 3.4937E-3 2 11 1 6292
positive regulation of gene-specific transcription 3.4937E-3 2 11 1 6292
cellular response to stimulus 3.6193E-3 2 379 2 6292
DNA unwinding involved in replication 4.4455E-3 2 14 1 6292
regulation of gene-specific transcription 4.7627E-3 2 15 1 6292
telomere maintenance via recombination 5.0798E-3 2 16 1 6292
postreplication repair 5.7138E-3 2 18 1 6292
DNA geometric change 6.3477E-3 2 20 1 6292
cellular response to organic substance 6.3477E-3 2 20 1 6292
DNA duplex unwinding 6.3477E-3 2 20 1 6292
RNA biosynthetic process 6.5067E-3 2 508 2 6292
double-strand break repair via homologous recombination 6.9813E-3 2 22 1 6292
cell morphogenesis involved in conjugation with cellular fusion 6.9813E-3 2 22 1 6292
cell morphogenesis involved in conjugation 7.6148E-3 2 24 1 6292
recombinational repair 8.248E-3 2 26 1 6292
DNA strand elongation 9.8303E-3 2 31 1 6292
DNA strand elongation involved in DNA replication 9.8303E-3 2 31 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

structure-specific DNA binding 4.7798E-5 2 44 2 6292
DNA binding 1.6492E-3 2 256 2 6292
chromatin DNA binding 2.5415E-3 2 8 1 6292
damaged DNA binding 3.4937E-3 2 11 1 6292
single-stranded DNA binding 5.0798E-3 2 16 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle