From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.638317512915] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
CLB4 |
|
|
|
MOB1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
microtubule organizing center | 9.8679E-5 | 2 | 63 | 2 | 6292 |
spindle pole body | 9.8679E-5 | 2 | 63 | 2 | 6292 |
spindle pole | 1.151E-4 | 2 | 68 | 2 | 6292 |
spindle | 1.9786E-4 | 2 | 89 | 2 | 6292 |
microtubule cytoskeleton | 2.8118E-4 | 2 | 106 | 2 | 6292 |
cytoskeletal part | 1.0156E-3 | 2 | 201 | 2 | 6292 |
cytoskeleton | 1.1732E-3 | 2 | 216 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
regulation of cell cycle | 4.3024E-4 | 2 | 131 | 2 | 6292 |
phosphorylation | 8.0494E-4 | 2 | 179 | 2 | 6292 |
phosphorus metabolic process | 1.3191E-3 | 2 | 229 | 2 | 6292 |
phosphate metabolic process | 1.3191E-3 | 2 | 229 | 2 | 6292 |
mitotic cell cycle | 1.6363E-3 | 2 | 255 | 2 | 6292 |
S phase of mitotic cell cycle | 3.1764E-3 | 2 | 10 | 1 | 6292 |
S phase | 3.1764E-3 | 2 | 10 | 1 | 6292 |
cell cycle phase | 3.5621E-3 | 2 | 376 | 2 | 6292 |
regulation of cyclin-dependent protein kinase activity | 4.4455E-3 | 2 | 14 | 1 | 6292 |
cell cycle process | 6.0534E-3 | 2 | 490 | 2 | 6292 |
cell cycle | 6.95E-3 | 2 | 525 | 2 | 6292 |
regulation of exit from mitosis | 7.9314E-3 | 2 | 25 | 1 | 6292 |
exit from mitosis | 7.9314E-3 | 2 | 25 | 1 | 6292 |
regulation of kinase activity | 8.248E-3 | 2 | 26 | 1 | 6292 |
regulation of protein kinase activity | 8.248E-3 | 2 | 26 | 1 | 6292 |
regulation of transferase activity | 8.248E-3 | 2 | 26 | 1 | 6292 |
G2/M transition of mitotic cell cycle | 9.1975E-3 | 2 | 29 | 1 | 6292 |
regulation of phosphorylation | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
kinase regulator activity | 5.9419E-5 | 2 | 49 | 2 | 6292 |
enzyme regulator activity | 1.0773E-3 | 2 | 207 | 2 | 6292 |
cyclin-dependent protein kinase regulator activity | 8.248E-3 | 2 | 26 | 1 | 6292 |