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Protein Overview: PI5K4_ARATH

General Information:
Name(s) found: PI5K4_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75181907|sp|Q9M1K2.1|PI5K4_ARATH RecName: Full=Putative phosphatidylinositol-4-phosphate 5-kinase 4; Short=AtPIP5K4; AltName: Full=1-phosphatidylinositol-4-phosphate kinase 4; AltName: Full=PtdIns(4)P-5-kinase 4; AltName: Full=Diphosphoinositide kinase [NCBI NR]
  • gi|6911866|emb|CAB72166.1| phosphatidylinositol-4-phosphate 5-kinase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|15230176|ref|NP_191255.1| PIP5K4 (PHOSPHATIDYL INOSITOL MONOPHOSPHATE 5 KINASE 4); 1-phosphatidylinositol-4-phosphate 5-kinase [Arabidopsis thaliana] [NCBI NR]
  • pir||T47756 phosphatidylinositol-4-phosphate 5-kinase-like protein - Arabidopsis thaliana [NCBI NR]
  • Phosphatidylinositol 4-phosphate 5-kinase 4 OS=Arabidopsis thaliana GN=PIP5K4 PE=3 SV=1 [Swiss-Prot]
  • (Q9M1K2) Phosphatidylinositol-4-phosphate 5-kinase-like protein [athaliana3702.FASTAC.txt]
  • phosphatidylinositol-4-phosphate 5-kinase-like protein [Arabidopsis thaliana]gi|11358617|pir||T47756 phosphatidylinositol-4-phosphate 5-kinase-like protein - Arabidopsis thalianagi|15230176|ref|NP_191255.1| phosphatidylinositol-4-phosphate 5-kinase fami [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Putative phosphatidylinositol-4-phosphate 5-kinase 4 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: PIP5K4 | PIP5K4 (PHOSPHATIDYL INOSITOL MONOPHOSPHATE 5 KINASE 4); 1-phosphatidylinositol-4-phosphate 5-kinase | chr3:21091936-21094864 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • phosphatidylinositol-4-phosphate 5-kinase-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 1-phosphatidylinositol-4-phosphate 5-kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Putative phosphatidylinositol-4-phosphate 5-kinase 4 (AtPIP5K4) (1-phosphatidylinositol-4-phosphate kinase 4) (PtdIns(4)P-5-kinase 4) (Diphosphoinositide kinase 4) [nr-271106-contam.fasta]
  • | Symbols: PIP5K4 | phosphatidyl inositol monophosphate 5 kinase 4 | chr3:21080957-21083885 FORWARD LENGTH=779 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Phosphatidylinositol 4-phosphate 5-kinase 4 OS=Arabidopsis thaliana GN=PIP5K4 PE=4 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 779 amino acids

    Gene Ontology:
    Cellular Component: cytosolic part [IDA]
    plasma membrane [IDA]
    apical plasma membrane [IDA]
    Biological Process: plant-type cell wall modification [IMP]
    establishment of tissue polarity [IMP]
    pollen tube growth [IGI][IMP]
    stomatal movement [IMP]
    phosphatidylinositol metabolic process [IDA]
    endocytosis [IMP]
    pollen germination [IGI]
    Molecular Function: 1-phosphatidylinositol-4-phosphate 5-kinase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKEQSCVLK AWEVTVRKTQ QAKKRANSIF GTVSVAPQTD DDATTTTEEN DDETSTNRSS  60
   61 IGELYHAERI LPNGDYYTGQ WYDSFPHGHG KYLWTDGCMY IGDWYNGKTM GRGKFGWPSG 120
  121 ATYEGEFKSG YMDGVGLYTG PSGDTYKGQW VMNLKHGHGI KRFANGDVYD GEWRRGLQEA 180
  181 QGKYQWRDGS YYMGEWKNAT ICGKGTFIWT DGNRYDGFWD DGFPRGNGTF KWADGSFYVG 240
  241 HWSNDPEEMN GTYYPSGDDG SPEWDPKDVF TNLSEYKICS GERVPVLPSQ KKLSVWNSSK 300
  301 RVEKPRRMSV DGRVSVGVDR AFEKMNMWGT ESGEGAADID STTRRDLDAE MMRLEAEGFI 360
  361 QSLRPSPAPM RLPRAGRKQG ETISKGHRNY ELMLNLQLGI RHAVGKQAPV VSLDLKHSAF 420
  421 DPKEKVWTRF PPEGTKYTPP HQSSEFKWKD YCPLVFRSLR KLFKVDPADY MLSICGNDAL 480
  481 RELSSPGKSG SFFYLTNDDR YMIKTMKKSE TKVLLRMLAA YYNHVRAFEN TLVIRFYGLH 540
  541 CVKLTGPIQK KVRFVIMGNL FCSEYSIHRR FDLKGSSLGR TTDKPESEIN SNTILKDLDL 600
  601 NFIFRLQKAW YQEFIRQVDK DCEFLEQERI MDYSLLVGIH FREASVAGEL IPSGARTPIG 660
  661 EFEDESAPRL SRADVDQLLS DPTRWASIRL GGNMPARAER TMRRSDCEFQ LVGEPTGEYY 720
  721 EVVMIFGIID ILQDYDISKK LEHAYKSIQY DPTSISAVDP RLYSRRFRDF IFKVFTEDN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..244] PSI-BLAST 7.522879 Crystal structure of the complete modular teichioic acid phosphorylcholine esterase Pce (CbpE) from Streptococcus pneumoniae
    2 View Details [245..370] PSI-BLAST 19.30103 Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; Histone H3 K4-specific methyltransferase SET7/9 catalytic domain
    3 View Details [371..779] PSI-BLAST 93.045757 Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • inositol or phosphatidylinositol kinase activity
    		•  4.06973114636425 bayes_pls_golite062009
  • phosphatidylinositol phosphate kinase activity
    		•  3.5005619620026 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  3.04766540645426 bayes_pls_golite062009
  • lipid kinase activity
    		•  3.03220928059157 bayes_pls_golite062009
  • 1-phosphatidylinositol-4-phosphate 5-kinase activity
    		•  3.00599233846946 bayes_pls_golite062009
  • kinase activity
    		•  2.85461858246731 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.23569102640176 bayes_pls_golite062009
  • catalytic activity
    		•  1.87792712964225 bayes_pls_golite062009
  • transferase activity
    		•  1.20817067352467 bayes_pls_golite062009
  • signal transducer activity
    		•  1.15068527302487 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.15068527302487 bayes_pls_golite062009
  • binding
    		•  1.02604095388529 bayes_pls_golite062009
  • protein kinase activity
    		•  0.887549500886727 bayes_pls_golite062009
  • protein binding
    		•  0.382966234080422 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.0651942184115614 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle