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Protein Overview: rnp-6

General Information:
Name(s) found: rnp-6 / CE24366 [WormBase]
Description(s) found:
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  • WBGene00004389 locus:rnp-6 status:Confirmed UniProt:Q9N3S4 protein_id:CCD72565.1 [WormBase]
  • gi|7331978|gb|AAF60666.1| Rnp (rrm rna binding domain) containing protein 6, isoform b [Caenorhabditis elegans] [NCBI NR]
  • gi|17510025|ref|NP_491176.1| RNP (RRM RNA binding domain) containing family member (rnp-6) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE24366 WBGene00004389 locus:rnp-6 RNA-binding protein status:Partially_confirmed TR:Q9N3S4 protein_id:AAF60666.1 [wormpep150.fasta]
  • 24366 WBGene00004389 locus:rnp-6 RNA-binding protein status:Partially_confirmed TR:Q9N3S4 protein_id:AAF60666.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • poly U binding factor 68kD like (rnp-6) [Caenorhabditis elegans]gi|7331978|gb|AAF60666.1| Rnp (rrm rna binding domain) containing protein 6, isoform b [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:rnp-6 RNA-binding protein status:Partially_confirmed TR:Q9N3S4 protein_id:AAF60666.1 [wormpep115.fasta.reversed]
  • CE24366 RNA-binding protein status:Partially_confirmed TR:Q9N3S4 protein_id:AAF60666.1 [wormpep80.hongbin]
  • CE24366 WBGene00004389 locus:rnp-6 RNA-binding protein status:Confirmed UniProt:Q9N3S4_CAEEL protein_id:AAF60666.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE24366 WBGene00004389 locus:rnp-6 RNA-binding protein status:Confirmed UniProt:Q9N3S4_CAEEL protein_id:AAF60666.1| [wormORF-contam.fasta]
  • Rnp (rrm rna binding domain) containing protein 6, isoform b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • RNP (RRM RNA binding domain) containing family member (rnp-6) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE24366 WBGene00004389 locus:rnp-6 RNA-binding protein status:Confirmed TR:Q9N3S4 protein_id:AAF60666.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE24366 WBGene00004389 locus:rnp-6 RNA-binding protein status:Confirmed UniProt:Q9N3S4 protein_id:AAF60666.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE24366 WBGene00004389 locus:rnp-6 RNA-binding protein status:Confirmed UniProt:Q9N3S4 protein_id:CCD72565.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE24366 WBGene00004389 locus:rnp-6 status:Confirmed UniProt:Q9N3S4 protein_id:CCD72565.1 [wormpep246-ecoli-contam.fasta]
  • RNP (RRM RNA binding domain) containing OS=Caenorhabditis elegans GN=rnp-6 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 749 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: hermaphrodite genitalia development [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    mRNA processing [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEENSADIEN RPVAAFRPAV SVPMPVLPQD GEVFVGPGGK KDAQKIGLGL SKLSSKRKDD  60
   61 IQMAKKYAMD ISIKQILLRQ QKQQQENQQR QQMYSQALSI MSRIYVGSIS FEIREDMLRR 120
  121 AFDPFGPIKS INMSWDPATG HHKTFAFVEY EVPEAALLAQ ESMNGQMLGG RNLKVNSMMF 180
  181 QEMRLPQNMP QAQPIIDMVQ KDAKKYFRVY VSSVHPDLSE TDLKSVFEAF GEIVKCQLAR 240
  241 APTGRGHRGF GYLEFNNLTS QSEAIAGMNM FDLGGQYLRV GKCVTPPDAL TYLQPASVSA 300
  301 IPASVSVACA AITAKVMAAE AAAGSSPKTP SESGGSRAAS PAPRAQSPAT PSSSLPTDIE 360
  361 NKAVISSPKK EPEEIEVPPL PPSAPDVVKD EPMEIEEEEE YTIPEEKPKP VAIVPPPGLA 420
  421 IPSLVAPPGL IAPTEIGIVV PNPSFLAQQQ QKIEEKIEEE EEARTERVKL STSQRKKMKR 480
  481 EKLNQMTFEE KMAQVLGQQK AVQNQRMADP VTFGALDDTV AWKDPSNEDQ TSEDGKMLAI 540
  541 MGPGRGGDNV ASMALALMDG GSSLMLANNA KAKEAAAALA LEPKKKKKVK EGKKIQPKLN 600
  601 TAQALAAAAK AGEMSDALKN EVMNSEDASL ASQEGLEIRG NDARHLLMTK LMRTNRSNVI 660
  661 VLRNMVTPQD IDEFLEGEIR EECGKYGNVI DVVIANFASS GLVKIFVKYS DSMQVDRAKA 720
  721 ALDGRFFGGN TVKAEAYDQI LFDHADYTG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..94] PSI-BLAST 26.0 No description for 2g4bA was found.
    2 View Details [95..299] PSI-BLAST 45.69897 Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
    3 View Details [300..388] deduced N/A No confident structure predictions are available.
    4 View Details [389..599] FFAS03 1.02 No description for 2j63A was found.
    5 View Details [600..749] PSI-BLAST 16.154902 CG8781 protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.10590295737522 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.43479844212501 bayes_pls_golite062009
  • RNA binding
    		•  0.426544317458995 bayes_pls_golite062009
  • protein binding
    		•  0.303849616374798 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  2.10590295737522 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.43479844212501 bayes_pls_golite062009
  • RNA binding
    		•  0.426544317458995 bayes_pls_golite062009
  • protein binding
    		•  0.303849616374798 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle