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Protein Overview: ced-10

General Information:
Name(s) found: ced-10 / CE16832 [WormBase]
Description(s) found:
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  • WBGene00000424 locus:ced-10 Ras-related protein ced-10 status:Confirmed UniProt:Q03206 protein_id:CCD64024.1 [WormBase]
  • gi|71982576|ref|NP_500362.3| CEll Death abnormality family member (ced-10) [Caenorhabditis elegans] [NCBI NR]
  • gi|2702398|gb|AAC25820.1| Cell death abnormality protein 10, isoform a [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • Cell death abnormality protein 10, isoform a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE16832 WBGene00000424 locus:ced-10 RAS-related protein status:Confirmed SW:Q03206 protein_id:AAC25820.1 [wormpep150.fasta]
  • 16832 WBGene00000424 locus:ced-10 RAS-related protein status:Confirmed SW:Q03206 protein_id:AAC25820.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • locus:ced-10 RAS-related protein status:Confirmed SW:Q03206 protein_id:AAC25820.1 [wormpep115.fasta.reversed]
  • CE16832 locus:ced-10 RAS-related protein status:Confirmed [wormpep80.hongbin]
  • CE16832 WBGene00000424 locus:ced-10 RAS-related protein status:Confirmed UniProt:RAC1_CAEEL protein_id:AAC25820.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE16832 WBGene00000424 locus:ced-10 RAS-related protein status:Confirmed UniProt:RAC1_CAEEL protein_id:AAC25820.1| [wormORF-contam.fasta]
  • CEll Death abnormality family member (ced-10) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE16832 WBGene00000424 locus:ced-10 RAS-related protein status:Confirmed UniProt:Q03206 protein_id:AAC25820.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE16832 WBGene00000424 locus:ced-10 RAS-related protein status:Confirmed UniProt:Q03206 protein_id:CCD64024.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE16832 WBGene00000424 locus:ced-10 status:Confirmed UniProt:Q03206 protein_id:CCD64024.1 Ras-related protein ced-10 [wormpep246-ecoli-contam.fasta]
  • Isoform of Q03206, Isoform b of Ras-related protein ced-10 OS=Caenorhabditis elegans GN=ced-10 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 129 amino acids

    Gene Ontology:
    Cellular Component: cytoplasmic vesicle [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    intracellular [IEALink to PubMed article]
    internal side of plasma membrane [IDALink to PubMed article]
    Biological Process: nucleocytoplasmic transport [IEALink to PubMed article]
    signal transduction [IEALink to PubMed article]
    small GTPase mediated signal transduction [IEALink to PubMed article]
    protein transport [IEALink to PubMed article]
    engulfment of apoptotic cell [IMPLink to PubMed article]
    intracellular protein transport [IEALink to PubMed article]
    cell migration [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: GTP binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]
    GTPase activity [IEALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGRP INLGLWDTAG  60
   61 QEDYDRLRER RLQPVSQTQG YVMAKEIKAV KYLECSALTQ RGLKQVFDEA IRAVLTPPQR 120
  121 AKKSKCTVL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] PSI-BLAST 34.522879 Rac

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  2.02893949194171 bayes_pls_golite062009
  • binding
    		•  2.00548409930693 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.97909493766908 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.95844964816653 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.95658009428828 bayes_pls_golite062009
  • transporter activity
    		•  1.442880936187 bayes_pls_golite062009
  • ATPase activity
    		•  1.42257610975945 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.34113621222575 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.28442352896828 bayes_pls_golite062009
  • DNA binding
    		•  1.16175440171961 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.05321763338965 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • hydrolase activity
    		•  0.98565595572967 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  0.732723553251109 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.725611289205392 bayes_pls_golite062009
  • nucleotide binding
    		•  0.717697610309727 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.713814218071151 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.713752628021599 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.388587892299301 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.372638007722845 bayes_pls_golite062009
  • GTP binding
    		•  0.364508542344128 bayes_pls_golite062009
  • GTPase activity
    		•  0.234351968078991 bayes_pls_golite062009
  • ATP binding
    		•  0.19169045543599 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.165732470448462 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.162060759063149 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.144154288308693 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.114463153989353 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle