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Protein Overview: prp11

General Information:
Name(s) found: prp11 / SPCC10H11.01 [Sanger Pombe]
Description(s) found:
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  • gi|7380876|emb|CAB85446.1| ATP-dependent RNA helicase Prp11 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|48474674|sp|Q9P7C7.1|PRP11_SCHPO RecName: Full=Pre-mRNA-processing ATP-dependent RNA helicase prp11 [NCBI NR]
  • gi|19075356|ref|NP_587856.1| ATP-dependent RNA helicase Prp11 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • ATP-dependent RNA helicase Prp11 [Sanger Pombe]
  • Pre-mRNA-processing ATP-dependent RNA helicase prp11 OS=Schizosaccharomyces pombe GN=prp11 PE=2 SV=1 [Swiss-Prot]
  • (Q9P7C7) Probable ATP-dependent RNA helicase prp11 [Swiss-Prot]
  • DEAD/DEAH BOX RNA HELICASE; PUTATIVE PRE-MRNA SPLICING FACTOR: Q9P7C7; [pompepVF.fasta]
  • DEAD/DEAH box RNA helicase [pompep4896]
  • |prp11||DEAD/DEAH box RNA helicase [pompepnew.fasta]
  • Probable ATP-dependent RNA helicase prp11 [4896.FASTAC]
  • |prp11||DEAD/DEAH box helicase|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • DEAD/DEAH box RNA helicase [Schizosaccharomyces pombe]gi|7380876|emb|CAB85446.1| SPCC10H11.01 [Schizosaccharomyces pombe]gi|48474674|sp|Q9P7C7|PR11_SCHPO Probable ATP-dependent RNA helicase prp11 [nrdb_11152004_Chlamydomonas]
  • (Q9P7C7) DEAD/DEAH box RNA helicase [pompep4896_normal_reversed]
  • |prp11||ATP-dependent RNA helicase Prp11|Schizosaccharomyces pombe|chr 3|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPCC10H11.01 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Pre-mRNA-processing ATP-dependent RNA helicase prp11 [nr-271106-contam.fasta]
  • SPCC10H11.01 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Pre-mRNA-processing ATP-dependent RNA helicase prp11 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=prp11 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 1014 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    spliceosomal complex [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: nuclear mRNA splicing, via spliceosome [ISSLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    ATP-dependent RNA helicase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRTRSRSP PRRSYNRERR DYRKYDDSED QKGARYNRYV DDVSSRRDRH DSFRSHESNK  60
   61 IRRDNSWKHD KYSYEKRYQE RDREYARSKN IPDQYIGRSP RPTSHRHAEE KEVDNKTKSD 120
  121 ETNPVLQGSA TEIKPQPRRS RFDRTERVGA SLSVSEIQSE NPRVDVIPKD KAVENNHQRN 180
  181 AEKPVASDKI TDAKLLARLE RVRAWKESKA KQEASKKEEH KLNTKPQVTA KDQNAMPSTG 240
  241 ISGFEINRQK DTSDMKRNNR VHMDDEDGPR RMNLEDYQEL WDQEDRGMLG NEQAASMEED 300
  301 EVDPLDAYMA SLVGTTDTIR PGLLNTEVID PNANDDERMV ISETLEEEEN LLALAAKRSK 360
  361 KKDVITVDHS KINYEDFKKD FYVEPEELKN LSPAEVDELR ASLDGIKIRG IDCPKPVTSW 420
  421 SQCGLSAQTI SVINSLGYEK PTSIQAQAIP AITSGRDVIG VAKTGSGKTI AFLLPMFRHI 480
  481 KDQRPLKTGE GPIAIIMTPT RELAVQIFRE CKPFLKLLNI RACCAYGGAP IKDQIADLKR 540
  541 GAEIVVCTPG RMIDVLSANA GRVTNLHRCT YLVLDEADRM FDLGFEPQVM RIINNIRPDR 600
  601 QTVLFSATFP RAMEALARKV LKKPVEITVG GRSVVASEVE QIVEVRPEES KFSRLLELLG 660
  661 ELYNNQLDVR TLVFVDRQES ADALLSDLMK RGYTSNSIHG GKDQHDRDST ISDYKAGVFD 720
  721 VLIATSVVAR GLDVKSLQLV VNYDCPNHME DYVHRVGRTG RAGHTGVAVT FITPEQEKYA 780
  781 VDIAKALKMS KQPVPKELQT LASQFLEKVK AGKEKAAGGG FGGKGLSRLD ETRNAERKMQ 840
  841 RKAYGEDEED VETEAEAKSP LEKITPEKST GDPTLDRVRA AVGGIAARAF ANQTAQSNKL 900
  901 TQPISIIKTD GDEYKAKMEI NDYPQQARWA VTNNTNIVHV TELTGTSITT KGNFYLPGKN 960
  961 PEPGEEKLYL WIEGPSELVV NRAITELRRL LLEGINHSLE GGNKPSASGR YTVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..238] deduced N/A No confident structure predictions are available.
    2 View Details [239..359] deduced N/A No confident structure predictions are available.
    3 View Details [360..437] FFAS03 1.05 No description for 2db3A was found.
    4 View Details [438..897] PSI-BLAST 17.69897 No description for 2v8oA was found.
    5 View Details [898..1014] FFAS03 2.89 RNA splicing factor 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • RNA binding
    		•  6.35205331138538 bayes_pls_golite062009
    		• 4.77327442333813 bayes_pls_golite062009
  • mRNA binding
    		•  4.67566555881601 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.53130750638836 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  3.73042056823822 bayes_pls_golite062009
  • translation regulator activity
    		•  3.73023228922019 bayes_pls_golite062009
  • binding
    		•  3.31439627344982 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.52775059206789 bayes_pls_golite062009
  • DNA binding
    		•  2.19723508219193 bayes_pls_golite062009
  • protein binding
    		•  2.14744035029318 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.98431295251845 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.87570901607985 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.84702374199408 bayes_pls_golite062009
  • hydrolase activity
    		•  1.79430008755254 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  1.75736205236351 bayes_pls_golite062009
  • transcription activator activity
    		•  1.69164969753194 bayes_pls_golite062009
  • transcription factor activity
    		•  1.23593912870728 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.11206973049533 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.925909354724523 bayes_pls_golite062009
  • signal transducer activity
    		•  0.820828954646689 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.820828954646689 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.795008427109843 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.684269812564476 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.370287528838428 bayes_pls_golite062009
  • transcription factor binding
    		•  0.227610374185311 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.150228013820667 bayes_pls_golite062009
  • catalytic activity
    		•  0.1435046019283 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.110425673333101 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle