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Protein Overview: SPBC1709.10c

General Information:
Name(s) found: SPBC1709.10c [Sanger Pombe]
Description(s) found:
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  • pir||T39638 probable metal homeostasis factor - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74626908|sp|O74735.1|ATX1_SCHPO RecName: Full=Metal homeostasis factor atx1 [NCBI NR]
  • gi|3738148|emb|CAA21249.1| copper chaperone Atx1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112235|ref|NP_595443.1| metallochaperone (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • metallochaperone [Sanger Pombe]
  • Metal homeostasis factor atx1 OS=Schizosaccharomyces pombe GN=atx1 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE METAL HOMEOSTASIS FACTOR; SIMILAR TO S. CEREVISIAE ATX1: O74735; [pompepVF.fasta]
  • PUTATIVE METAL HOMEOSTASIS FACTOR: O74735; [pompepV13]
  • Putative metal homeostasis factor [pompep4896]
  • |||putative metal homeostasis factor [pompepnew.fasta]
  • SPBC1709.10c protein [4896.FASTAC]
  • |||heavy metal binding protein (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative metal homeostasis factor [Schizosaccharomyces pombe]gi|3738148|emb|CAA21249.1| SPBC1709.10c [Schizosaccharomyces pombe]gi|7492713|pir||T39638 probable metal homeostasis factor - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||metallochaperone |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O74735) Putative metal homeostasis factor [pompep4896_normal_reversed]
  • |atx1||copper chaperone Atx1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC1709.10c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • heavy metal-binding protein [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Metal homeostasis factor atx1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=atx1 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 68 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: cellular copper ion homeostasis [IMPLink to PubMed article]
    regulation of iron ion transmembrane transport [IMPLink to PubMed article]
    intracellular copper ion transport [TASLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    copper chaperone activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYQFNVAMA CDGCKNAIDR VLTRLGVEDK SISVEKQEVI VTTDKPYELV EQTIKKTGKE  60
   61 VRSGKVLE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] PSI-BLAST 11.09691 FOURTH METAL-BINDING DOMAIN OF THE MENKES COPPER-TRANSPORTING ATPASE, NMR, 20 STRUCTURES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • copper chaperone activity
    		•  6.14761367748172 bayes_pls_golite062009
  • metallochaperone activity
    		•  5.42894566783157 bayes_pls_golite062009
  • copper ion binding
    		•  5.41725082570189 bayes_pls_golite062009
  • copper-dependent protein binding
    		•  4.95395467138629 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  4.35398003989182 bayes_pls_golite062009
  • copper-exporting ATPase activity
    		•  4.01340421656566 bayes_pls_golite062009
  • copper-transporting ATPase activity
    		•  3.98014937932947 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  3.67313485213724 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  3.36143792136115 bayes_pls_golite062009
  • superoxide dismutase copper chaperone activity
    		•  3.30291073809164 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.07976644601593 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.00431429991351 bayes_pls_golite062009
  • binding
    		•  2.93936761631807 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  2.81498319767782 bayes_pls_golite062009
  • metal ion binding
    		•  2.69806984896689 bayes_pls_golite062009
  • cation binding
    		•  2.69806984896689 bayes_pls_golite062009
  • ion binding
    		•  2.69078950610234 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.64028711724976 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.63703148987083 bayes_pls_golite062009
  • transition metal ion binding
    		•  2.52520930681159 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
    		•  2.38802353099961 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.89914790023437 bayes_pls_golite062009
  • protein binding
    		•  0.989113446856899 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.841996187774093 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.508360443861132 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.470327716716451 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.452477805627897 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.45132236262635 bayes_pls_golite062009
  • ATPase activity
    		•  0.392266185712579 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle