General Information: |
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Name(s) found: |
DRD4_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 387 amino acids |
Gene Ontology: |
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Cellular Component: |
integral to plasma membrane
[UNKNOWN]
dendrite [IDA] cytoplasm [IDA] terminal button [IDA] cell cortex [IDA] vesicle membrane [IDA] membrane [UNKNOWN] dendritic spine [IDA] integral to membrane [IEA] neuronal cell body [IDA] plasma membrane [IDA][NAS] axon [IDA] |
Biological Process: |
negative regulation of adenylate cyclase activity
[UNKNOWN]
inhibition of adenylate cyclase activity by dopamine receptor signaling pathway [UNKNOWN][IEA] negative regulation of calcium ion transport via voltage-gated calcium channel activity [UNKNOWN] dopamine receptor signaling pathway [UNKNOWN][IDA] adult locomotory behavior [UNKNOWN][IEA] fear response [UNKNOWN] associative learning [IMP] activation of MAPK activity [UNKNOWN] synaptic transmission, dopaminergic [IDA][IMP] locomotory behavior [TAS] behavioral response to cocaine [UNKNOWN][IEA] positive regulation of kinase activity [UNKNOWN] regulation of neurotransmitter secretion [IMP] signal transduction [IEA] negative regulation of protein secretion [UNKNOWN] negative regulation of cAMP biosynthetic process [UNKNOWN] olfactory learning [IMP] behavioral fear response [IMP] short-term memory [IMP] positive regulation of sodium:hydrogen antiporter activity [UNKNOWN] response to amphetamine [UNKNOWN][IEA] arachidonic acid secretion [UNKNOWN] regulation of dopamine metabolic process [UNKNOWN][IEA] response to histamine [UNKNOWN] regulation of inhibitory postsynaptic membrane potential [UNKNOWN][IEA] regulation of synaptic transmission [IDA] regulation of calcium-mediated signaling [IMP] |
Molecular Function: |
G-protein coupled receptor activity
[IEA]
dopamine receptor activity [UNKNOWN][IEA] protein binding [UNKNOWN] drug binding [UNKNOWN][IDA] dopamine binding [UNKNOWN][IDA] dopamine receptor activity, coupled via Gi/Go [UNKNOWN] SH3 domain binding [UNKNOWN] dopamine D4 receptor activity [UNKNOWN][IDA][TAS] receptor activity [IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MGNSSATGDG GLLAGRGPES LGTGTGLGGA GAAALVGGVL LIGMVLAGNS LVCVSVASER 60 61 ILQTPTNYFI VSLAAADLLL AVLVLPLFVY SEVQGGVWLL SPRLCDTLMA MDVMLCTASI 120 121 FNLCAISVDR FVAVTVPLRY NQQGQCQLLL IAATWLLSAA VAAPVVCGLN DVPGRDPTVC 180 181 CLEDRDYVVY SSICSFFLPC PLMLLLYWAT FRGLRRWEAA RHTKLHSRAP RRPSGPGPPV 240 241 SDPTQGPLFS DCPPPSPSLR TSPTVSSRPE SDLSQSPCSP GCLLPDAALA QPPAPSSRRK 300 301 RGAKITGRER KAMRVLPVVV GAFLMCWTPF FVVHITRALC PACFVSPRLV SAVTWLGYVN 360 361 SALNPIIYTI FNAEFRSVFR KTLRLRC |
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