General Information: |
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Name(s) found: |
TGFB2_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 442 amino acids |
Gene Ontology: |
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Cellular Component: |
platelet alpha granule lumen
[UNKNOWN]
basement membrane [IDA] extracellular space [UNKNOWN][IDA] trans-Golgi network [IDA] cytoplasm [IDA] secretory granule [IDA] extracellular matrix [UNKNOWN] neuronal cell body [ISS] extracellular region [UNKNOWN][ISS] axon [ISS] cell surface [IDA] |
Biological Process: |
cell cycle arrest
[UNKNOWN]
dopamine biosynthetic process [ISS] frontal suture morphogenesis [IEP] positive regulation of phosphoinositide 3-kinase cascade [UNKNOWN] positive regulation of integrin biosynthetic process [UNKNOWN] response to estrogen stimulus [IDA] inner ear development [IEP] response to progesterone stimulus [UNKNOWN] transforming growth factor beta receptor signaling pathway [UNKNOWN] response to radiation [IEP] axon guidance [UNKNOWN][IEA] menstrual cycle phase [UNKNOWN] glial cell migration [UNKNOWN] heart morphogenesis [UNKNOWN] positive regulation of cell growth [UNKNOWN][ISS] response to retinoic acid [IEP] wound healing [IEP][IMP][ISS] skeletal system development [UNKNOWN][IEA] response to hypoxia [UNKNOWN] cell death [UNKNOWN][ISS] cartilage condensation [UNKNOWN][IEA] hair follicle development [UNKNOWN][ISS] kidney development [IEP] induction of apoptosis [UNKNOWN][IEA] negative regulation of cell growth [UNKNOWN] hindbrain development [IEP] gut development [IEP] positive regulation of protein secretion [UNKNOWN] cell morphogenesis [UNKNOWN][ISS] SMAD protein nuclear translocation [UNKNOWN] cardiac epithelial to mesenchymal transition [UNKNOWN] regulation of apoptosis [UNKNOWN] cardiac muscle cell proliferation [UNKNOWN][ISS] cell-cell junction organization [UNKNOWN] positive regulation of ossification [UNKNOWN] activation-induced cell death of T cells [UNKNOWN][IEA] response to laminar fluid shear stress [IEP] positive regulation of cardioblast differentiation [UNKNOWN][ISS] regulation of cell growth [TAS] negative regulation of epithelial cell proliferation [UNKNOWN] response to estradiol stimulus [IEP] epithelial to mesenchymal transition [UNKNOWN] hair follicle morphogenesis [ISS] cell growth [IEA] positive regulation of stress-activated MAPK cascade [UNKNOWN] positive regulation of cell migration [IDA] response to cytokine stimulus [IEP] catagen [UNKNOWN][ISS] response to vitamin D [IEP] negative regulation of cell proliferation [UNKNOWN][IMP][ISS] hemopoiesis [ISS] positive regulation of cell proliferation [UNKNOWN][IDA][ISS] response to wounding [UNKNOWN] positive regulation of cell cycle [ISS] regulation of transforming growth factor-beta2 production [UNKNOWN] protein amino acid phosphorylation [UNKNOWN] positive regulation of heart contraction [UNKNOWN][ISS] pathway-restricted SMAD protein phosphorylation [UNKNOWN][IEA] positive regulation of neuron apoptosis [UNKNOWN][ISS] salivary gland morphogenesis [UNKNOWN] positive regulation of epithelial to mesenchymal transition [UNKNOWN] heart development [UNKNOWN][ISS] response to cold [IEP] blood vessel development [UNKNOWN][IEA] positive regulation of cell division [IEA] somatic stem cell division [ISS] neuron fate commitment [UNKNOWN][IEA] activation of protein kinase activity [UNKNOWN] positive regulation of cell adhesion mediated by integrin [UNKNOWN] positive regulation of epithelial cell migration [UNKNOWN] negative regulation of immune response [IDA] cell migration [UNKNOWN] positive regulation of immune response [ISS] lung development [TAS] pancreas development [IEP] negative regulation of alkaline phosphatase activity [UNKNOWN] embryonic neurocranium morphogenesis [IDA] female pregnancy [IEP] negative regulation of release of sequestered calcium ion into cytosol [IDA] neuron development [ISS] aging [IEP] regulation of cell proliferation [TAS] eye development [UNKNOWN][ISS] blood vessel remodeling [UNKNOWN][IEA] thyroid gland development [IEP] positive regulation of catagen [UNKNOWN][ISS] skeletal muscle tissue development [IEP] response to drug [IEP] negative regulation of apoptosis [IDA] positive regulation of apoptosis [UNKNOWN][IMP] extracellular matrix organization [UNKNOWN][IEA] neutrophil chemotaxis [ISS] collagen fibril organization [UNKNOWN] cardioblast differentiation [UNKNOWN][ISS] response to organic nitrogen [IEP] |
Molecular Function: |
receptor signaling protein serine/threonine kinase activity
[UNKNOWN]
growth factor activity [IEA] protein binding [UNKNOWN] protein homodimerization activity [UNKNOWN][IDA][ISS] transforming growth factor beta receptor binding [UNKNOWN][IEA][ISS][TAS] protein heterodimerization activity [IDA] protein N-terminus binding [IMP] type II transforming growth factor beta receptor binding [UNKNOWN] receptor binding [UNKNOWN][ISS] beta-amyloid binding [UNKNOWN][ISS] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MHYCVLRTFL LLHLVPVALS LSTCSTLDMD QFMRKRIEAI RGQILSKLKL TSPPEDYPEP 60 61 DEVPPEVISI YNSTRDLLQE KASRRAAACE RERSDEEYYA KEVYKIDMPS HFPSETVCPV 120 121 VTTSSGSVGS FCSIQSQVLC GYLDAIPPTF YRPYFRIVRF DVSTMEKNAS NLVKAEFRVF 180 181 RLQNPKARVA EQRIELYQIL KSKDLTSPTQ RYIDSKVVKT RAEGEWLSFD VTDAVHEWLH 240 241 HKDRNLGFKI SLHCPCCTFI PSNNYIIPNK SQELEARFAG IDGTSTYASG DQKTIKSTRK 300 301 KSSGKTPHLL LMLLPSYRLE SQQSSRRRKR ALDAAYCFRN VQDNCCLRPL YIDFKRDLGW 360 361 KWIHEPKGYN ANFCAGACPY LWSSDTQHTK VLSLYNTINP EASASPCCVS QDLEPLTILY 420 421 YIGNTPKIEQ LSNMIVKSCK CS |
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