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Protein Overview: GNT1

General Information:
Name(s) found: GNT1 / YOR320C [SGD]
Description(s) found:
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  • gi|940851|emb|CAA62175.1| orf 06145 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|74583804|sp|Q12096.1|GNT1_YEAST RecName: Full=Glucose N-acetyltransferase 1; AltName: Full=N-acetylglucosaminyltransferase [NCBI NR]
  • gi|6324896|ref|NP_014965.1| N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus; Gnt1p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S58330 probable membrane protein YOR320c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1420702|emb|CAA99640.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • Glucose N-acetyltransferase 1 OS=Saccharomyces cerevisiae GN=GNT1 PE=1 SV=1 [Swiss-Prot]
  • GNT1 N-acetylglucosaminyltransferase transferase capable of modification of N-linked glycans in the Golgi apparatus [mips]
  • N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus [SGD]
  • >Q12096 (Q12096) Chromosome XV reading frame ORF YOR320C [4932.FASTACCERV.txt]
  • Chr XV from 915087-913612, reverse complement [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XV from 913611-915086, reverse complement [yeastorf3.fasta]
  • Chr XV from 913612-915087, reverse complement [yeastorf4.fasta]
  • YOR320C, Chr XV from 913611-915086, reverse complement [yeast_orfs2]
  • GNT1 SGDID:S0005847, Chr XV from 915089-913614, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Gnt1p [Saccharomyces cerevisiae]gi|1420702|emb|CAA99640.1| unnamed protein product [Saccharomyces cerevisiae]gi|940851|emb|CAA62175.1| orf 06145 [Saccharomyces cerevisiae]gi|2132946|pir||S58330 probable membrane protein YOR320c - yeast (Saccharomyces c [nrdb_11152004_Chlamydomonas]
  • (Q12096) S.cerevisiae chromosome XV reading frame ORF YOR320c (Orf 06145 protein) [cerv4932.FASTAC]
  • GNT1 SGDID:S000005847, Chr XV from 915089-913614, reverse complement, Verified ORF, "N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • GNT1 SGDID:S000005847, Chr XV from 915091-913616, reverse complement, Verified ORF, "N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus" [yeast-contam.fasta]
  • N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus; Gnt1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Glucose N-acetyltransferase 1 (N-acetylglucosaminyltransferase) [nr-271106-contam.fasta]
  • orf 06145 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Glucose N-acetyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GNT1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • GNT1 SGDID:S000005847, Chr XV from 915094-913619, Genome Release 64-1-1, reverse complement, Verified ORF, "N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus" [yeast-030211-contam.fasta]
  • GNT1 SGDID:S000005847, Chr XV from 915094-913619, Genome Release 64-2-1, reverse complement, Verified ORF, "N-acetylglucosaminyltransferase; capable of modification of N-linked glycans in the Golgi apparatus" [20141208_orf_trans.fasta]
  • YOR320C SGDID:S000005847, Chr XV from 915094-913619, Genome Release 64-1-1, reverse complement, Verified ORF, "N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 491 amino acids

    Gene Ontology:
    Cellular Component: Golgi medial cisterna [IDALink to PubMed article]
    Biological Process: protein amino acid N-linked glycosylation [IMPLink to PubMed article]
    Molecular Function: acetylglucosaminyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLISKRRIR FIVFILFGVL TVFVVSRLVV HFQYNQEIKF YKKYFQQRKD GLHEIYNPLE  60
   61 IKQIPKETID DLYTARLDKE LKNGEVIEWS KFAYVNYVTN ADYLCNTLII FNDLKQEFET 120
  121 KAKLVLLISK DLLDPNTSSN VAYISSLLNK IQAIDEDQVV IKLIDNIVKP KDTTPWNESL 180
  181 TKLLVFNQTE FDRVIYLDND AILRSSLDEL FFLPNYIKFA APLTYWFLSN SDLEKSYHET 240
  241 RHREKQPINL QSYTKVLTKR IGKGQMIYNH LPSLPHSLYL NSNNIAQDII SSTSSLSPLF 300
  301 DFQSSKKVGK LKFASNLMVI NPSKEAFDEI VNVMLPKILN KKEKYDMDLI NEEMYNLKKI 360
  361 IYKQFIFFRK VRKLFKPEVL VLPFARYGLL TGSLRNPRHY SIIYNDVLGY KTLDNDGNDI 420
  421 PVGLNDSVAY SKYIHFSDYP LAKPWNYPSM KEFECIVKEE DAEDSKLEHQ ACDLWNSVYA 480
  481 SYIQSREICL V

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ANP1 GNT1 HOC1 KTR1 KTR4 MNN1 MNN10 MNN11 MNN5 MNN9 OCH1 VAN1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run VAM3 Sample: HX14 - mixture in detergent (control). Hao Xu, et al. (2010)
    View Run None Entered #17 Mitotic Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data GNT1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] deduced N/A No confident structure predictions are available.
    2 View Details [83..340] PSI-BLAST 42.09691 Glycogenin
    3 View Details [341..491] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • UDP-glycosyltransferase activity
    		•  6.50620584399191 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  6.18010634203776 bayes_pls_golite062009
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  6.10775566377356 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  5.57855076532185 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  4.57071306027628 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  4.49413422196176 bayes_pls_golite062009
  • alpha-1,2-mannosyltransferase activity
    		•  3.80392076707564 bayes_pls_golite062009
  • transferase activity
    		•  2.62166586999833 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.01768771829228 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.31793036737589 bayes_pls_golite062009
  • lactose synthase activity
    		•  1.27388044382276 bayes_pls_golite062009
  • N-acetyllactosamine synthase activity
    		•  1.27388044382276 bayes_pls_golite062009
  • alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
    		•  0.734643988700831 bayes_pls_golite062009
  • glucuronosyltransferase activity
    		•  0.36353543999278 bayes_pls_golite062009
  • uridylyltransferase activity
    		•  0.321928989676507 bayes_pls_golite062009
  • UDP-galactosyltransferase activity
    		•  0.10185872015123 bayes_pls_golite062009
  • galactosyltransferase activity
    		•  0.0931461042017721 bayes_pls_golite062009
  • binding
    		•  0.074398891333042 bayes_pls_golite062009
  • acetylglucosaminyltransferase activity
    		•  0.0278258721775009 bayes_pls_golite062009
  • galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
    		•  0.00787862255329008 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle