YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: NOP8

General Information:
Name(s) found: NOP8 / YOL144W [SGD]
Description(s) found:
SHOW ONLY BEST
  • gi|6324428|ref|NP_014497.1| Nucleolar protein required for 60S ribosomal subunit biogenesis; Nop8p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S61870 hypothetical protein YOL144w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1420044|emb|CAA99165.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|13878589|sp|Q08287.1|NOP8_YEAST RecName: Full=60S ribosome subunit biogenesis protein NOP8; AltName: Full=Nucleolar protein 8 [NCBI NR]
  • 60S ribosome subunit biogenesis protein NOP8 OS=Saccharomyces cerevisiae GN=NOP8 PE=1 SV=1 [Swiss-Prot]
  • NOP8 Nucleolar protein required for 60S ribosome biogenesis [mips]
  • Nucleolar protein required for 60S ribosomal subunit biogenesis [SGD]
  • (Q08287) 60S ribosome subunit biogenesis protein NOP8 [4932.FASTACCERV.txt]
  • Chr XV from 53096-54550 [hmr_yeast5_DM3-1_pombe.fasta]
  • NOP8, Chr XV from 53096-54550 [yeast_orfs2]
  • NOP8 SGDID:S0005504, Chr XV from 53096-54550, Verified ORF [yeastflysequest.fasta]
  • Nop8p [Saccharomyces cerevisiae]gi|1420044|emb|CAA99165.1| unnamed protein product [Saccharomyces cerevisiae]gi|2132021|pir||S61870 hypothetical protein YOL144w - yeast (Saccharomyces cerevisiae)gi|13878589|sp|Q08287|NOP8_YEAST 60S ribosome subunit bio [nrdb_11152004_Chlamydomonas]
  • NOP8 SGDID:S000005504, Chr XV from 53096-54550, Verified ORF, "Nucleolar protein required for 60S ribosomal subunit biogenesis" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • NOP8 SGDID:S000005504, Chr XV from 53097-54551, Verified ORF, "Nucleolar protein required for 60S ribosomal subunit biogenesis" [yeast-contam.fasta]
  • 60S ribosome subunit biogenesis protein NOP8 (Nucleolar protein 8) [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Nucleolar protein required for 60S ribosomal subunit biogenesis; Nop8p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • 60S ribosome subunit biogenesis protein NOP8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOP8 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • NOP8 SGDID:S000005504, Chr XV from 53098-54552, Genome Release 64-1-1, Verified ORF, "Nucleolar protein required for 60S ribosomal subunit biogenesis" [yeast-030211-contam.fasta]
  • NOP8 SGDID:S000005504, Chr XV from 53098-54552, Genome Release 64-2-1, Verified ORF, "Nucleolar protein required for 60S ribosomal subunit biogenesis" [20141208_orf_trans.fasta]
  • YOL144W SGDID:S000005504, Chr XV from 53098-54552, Genome Release 64-1-1, Verified ORF, "Nucleolar protein required for 60S ribosomal subunit biogenesis" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 484 amino acids

    Gene Ontology:
    Cellular Component: nucleolus [TASLink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    rRNA processing [TASLink to PubMed article]
    ribosomal large subunit assembly [TASLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSVIQKRIF VGNIFHNADD CYSELLDRFG KFGDCQDFQF EKHNHFAFID IRFNDEADFN  60
   61 KLRKSFNNVK FKGNILKVDE AKPNWESTWA VQHAKDLKED IILNAKMKKK NWQHYKKMEN 120
  121 VAKSWKDHKE VIAGRMREAP RKRSQLRNIT FRINVNGSLK VYKCYKTKLW GYERNKELND 180
  181 LVYKFTNNFW KNGYNHIVDR LDYSRAVKTV RFKNGLKQLT VSKDENVCSG EMDSDENMSE 240
  241 EEKEKNNVIL NDLLKDFDFD KPMTLNDSDE ELLTEQRKGE EEEEEEEEKE VNAPEYENVN 300
  301 KTKDQSTLPQ EKPEERKEQD EGDGQEDNEF IPTFTKEIGQ GTISNTETLR NLFNPNEAEP 360
  361 VSQFKLIEDS DNDIDHAKDV DVNQLEEEVS KSSDTLGLTS APVPHVSRDK DNKNFLFFPH 420
  421 LQSPFLVGQT QLSKVRAPGR ETMLSNWDEE FWANRGNWTR DMRRKMKDAL KHRKRKQSKS 480
  481 GLLL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) NOP8 URB1
    View Details Krogan NJ, et al. (2006) BUD22 CIC1 DBP6 EFG1 FRE3 GIS2 HAS1 MAK21 NIP7 NOB1 NOC2 NOC3 NOP1 NOP2 NOP8 PUS7 RRP5 RSA3 SBP1 SFA1 SSQ1 YGR272C YMR034C YRF1-8, YRF1-5, ...
    View Details Gavin AC, et al. (2006) NOP8 URB1 URB2
    View Details Qiu et al. (2008) DRS1 GAR1 NOP8 NSR1 NUG1 PXR1 UTP5 UTP6 UTP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ESF1 No Comments Hazbun TR, et al. (2003)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data NOP8 Huh WK, et al. (2003)
    View Data NOP8 and NOP56 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] PSI-BLAST 8.0 Sex-lethal protein
    2 View Details [156..484] deduced N/A No confident structure predictions are available.
    3 View Details [328..389] deduced N/A No confident structure predictions are available.
    4 View Details [390..484] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  3.72964573417386 bayes_pls_golite062009
  • binding
    		•  3.0101982407193 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.34356093608328 bayes_pls_golite062009
    		• 1.46562488829931 bayes_pls_golite062009
  • structural molecule activity
    		•  1.10982714865204 bayes_pls_golite062009
  • protein binding
    		•  0.89093640300829 bayes_pls_golite062009
  • mRNA binding
    		•  0.554135435832456 bayes_pls_golite062009
  • ribosomal large subunit binding
    		•  0.13509933485234 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle