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Protein Overview: ARG81

General Information:
Name(s) found: ARG81 / YML099C [SGD]
Description(s) found:
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  • gi|6323539|ref|NP_013610.1| Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p; Arg81p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|575703|emb|CAA86638.1| ARGR2 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1351976|sp|P05085.3|ARGR2_YEAST RecName: Full=Arginine metabolism regulation protein II [NCBI NR]
  • pir||S49627 regulatory protein ARGR2 - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Arginine metabolism regulation protein II OS=Saccharomyces cerevisiae GN=ARGR2 PE=1 SV=3 [Swiss-Prot]
  • (P05085) Arginine metabolism regulation protein II [Swiss-Prot]
  • ARG81 Transcription factor involved in arginine metabolism [mips]
  • Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p [SGD]
  • ARG81, Chr XIII from 74398-77040, reverse complement [yeast_orfs2]
  • Chr XIII from 74398-77040, reverse complement [yeastorf3.fasta]
  • Chr XIII from 77040-74398, reverse complement [yeastorf5.fasta]
  • ARG81 SGDID:S0004565, Chr XIII from 77040-74398, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Arg81p [Saccharomyces cerevisiae]gi|575703|emb|CAA86638.1| ARGR2 [Saccharomyces cerevisiae]gi|1351976|sp|P05085|ARG2_YEAST Arginine metabolism regulation protein IIgi|1078323|pir||S49627 regulatory protein ARGR2 - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas]
  • ARG81 SGDID:S000004565, Chr XIII from 77040-74398, reverse complement, Verified ORF, "Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p; Arg81p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • ARGR2 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Arginine metabolism regulation protein II [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Arginine metabolism regulation protein II OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARG81 PE=1 SV=3 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • ARG81 SGDID:S000004565, Chr XIII from 77040-74398, Genome Release 64-1-1, reverse complement, Verified ORF, "Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p" [yeast-030211-contam.fasta]
  • ARG81 SGDID:S000004565, Chr XIII from 77040-74398, Genome Release 64-2-1, reverse complement, Verified ORF, "Zinc finger transcription factor involved in arginine-responsive genes; Zn(2)-Cys(6) binuclear cluster domain type; involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p" [20141208_orf_trans.fasta]
  • YML099C SGDID:S000004565, Chr XIII from 77040-74398, Genome Release 64-1-1, reverse complement, Verified ORF, "Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 880 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: arginine metabolic process [TASLink to PubMed article]
    negative regulation of calcium ion-dependent exocytosis [IDALink to PubMed article]
    Molecular Function: transcription cofactor activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGISSKNGPK KMGRAKTFTG CWTCRGRKVK CDLRHPHCQR CEKSNLPCGG YDIKLRWSKP  60
   61 MQFDPYGVPI PQNSPATTTN LSGSVDEPQY QRRNIDFVRY DEEYVYHEDM DDELTMLHTP 120
  121 PIEKISDNKT WIIKKFGVFK GTDKIDKQYA PRKKRNRKRV AKSLESSASI SLSSLPSSST 180
  181 ISFPIRHIED KLRNKGHVKT GILSANDGVP PTPNLLDYDW NNLNITGYEW ISSELRDDAL 240
  241 LSAVTLQGHH LGHTQPQEIS LEENSNVVSG EEHVNAKEHG CAFEADNQGS STLPNKAASA 300
  301 NDKLYQQNLK LLFQKNSSNS EEPDPQALID DVFVNIEPRS LPASDLNKIT LAPPNEESRM 360
  361 PKSMLELTSY SSDLPPELVD IIPKTDLTVH GLARFLLNHY FNNVADKMTV VVLEKNPWKT 420
  421 LYFPRALMAL GDLAGLGQSS NSRNALLNAL LAVSCFHLQS KYPRNYKLQK YFLGLGIELR 480
  481 NQASNFLRLC LNTKSSIPEK YKDVLTAILS MNSIDVVWGT MADCQDHLAL CEDFVESRMK 540
  541 LRPNISEKTK TLHRIFSFLK LIQDSTALDK VRAKEIVILP SEEDDNYKPL DTSNATTSSS 600
  601 EPRVDVVQEG LFREALNEND GKIHIEFVKE PITNVSADST PSSTTPPIFT NIATESYYNK 660
  661 SDISKLVSKT DENIIGTDSL YGLPNSLILL FSDCVRIVRH NEYYNLTYLP VPRKFNELSL 720
  721 NFEKRLLKWK SEWNFHQENS EGKSFINSTA EALYHHTMSF YFSLIIYYFT MARSLNCQFL 780
  781 QNYVAKVLDH LNAMEELVDQ KKVKIVPLIW QGFMAGCACT DENRQQEFRR WAAKLAESGV 840
  841 GSYWGARQVM LEVWRRRKED EPGDNWYSVY KDWEMNLMLS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) ARG80 ARG81 ARG82 MCM1
    View Details Qiu et al. (2008) ARG80 ARG81

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen KSS1 ARG81 2 Unpublished Fields Lab Data
    View Screen YJL147C ARG81 2 Unpublished Fields Lab Data
    View Screen RPT1 ARG81 2 Unpublished Fields Lab Data
    View Screen IMP4 ARG81 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ARG81 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] PSI-BLAST 46.68867 PPR1
    2 View Details [70..880] deduced N/A No confident structure predictions are available.
    3 View Details [205..295] deduced N/A No confident structure predictions are available.
    4 View Details [296..355] deduced N/A No confident structure predictions are available.
    5 View Details [356..580] MSA 1.021996 View MSA. No confident structure predictions are available.
    6 View Details [581..671] deduced N/A No confident structure predictions are available.
    7 View Details [672..880] MSA 2.016989 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.91929847152301 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.7831619208765 bayes_pls_golite062009
  • DNA binding
    		•  2.61829684541806 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.43465257824542 bayes_pls_golite062009
  • transcription factor activity
    		•  1.55251487621784 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.87785810571597 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.83092951524649 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.79838087621523 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle