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Protein Overview: MAG2

General Information:
Name(s) found: MAG2 / YLR427W [SGD]
Description(s) found:
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  • gi|74655013|sp|Q06436.1|MAG2_YEAST RecName: Full=RING-finger protein MAG2 [NCBI NR]
  • gi|664874|gb|AAB67504.1| Ylr427wp [Saccharomyces cerevisiae] [NCBI NR]
  • gi|6323459|ref|NP_013531.1| Cytoplasmic protein of unknown function predicted to encode a DNA-3-methyladenine glycosidase II that catalyzes the hydrolysis of alkylated DNA; Mag2p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|51012907|gb|AAT92747.1| YLR427W [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S53414 probable membrane protein YLR427w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • RING-finger protein MAG2 OS=Saccharomyces cerevisiae GN=MAG2 PE=1 SV=1 [Swiss-Prot]
  • MAG2 Protein of unknown function [mips]
  • Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1 [SGD]
  • YLR427W, Chr XII from 988423-990435 [yeast_orfs2]
  • Chr XII from 988423-990435 [yeastorf3.fasta]
  • >Q06436 (Q06436) Chromosome XII COSMID 9576 [4932.FASTACCERV.txt]
  • MAG2 SGDID:S0004419, Chr XII from 988424-990436, Uncharacterized ORF [yeastflysequest.fasta]
  • Mag2p [Saccharomyces cerevisiae]gi|51012907|gb|AAT92747.1| YLR427W [Saccharomyces cerevisiae]gi|1078084|pir||S53414 probable membrane protein YLR427w - yeast (Saccharomyces cerevisiae)gi|664874|gb|AAB67504.1| Ylr427wp [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas]
  • (Q06436) Ylr427wp (YLR427W) [cerv4932.FASTAC]
  • MAG2 SGDID:S000004419, Chr XII from 988424-990436, Uncharacterized ORF, "DNA-3-methyladenine glycosidase II that catalyzes of the hydrolysis of alkylated DNA" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • MAG2 SGDID:S000004419, Chr XII from 988425-990437, Uncharacterized ORF, "DNA-3-methyladenine glycosidase II that catalyzes of the hydrolysis of alkylated DNA" [yeast-contam.fasta]
  • MAG2 SGDID:S000004419, Chr XII from 988425-990437, Verified ORF, "Cytoplasmic protein of unknown function predicted to encode a DNA-3-methyladenine glycosidase II that catalyzes the hydrolysis of alkylated DNA" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • MAG2 SGDID:S000004419, Chr XII from 988425-990437, Verified ORF, "Cytoplasmic protein of unknown function, predicted by computational analysis of interaction data to encode a DNA-3-methyladenine glycosidase II that catalyzes the hydrolysis of alkylated DN [yeast-200209-contam.fasta]
  • MAG2 SGDID:S000004419, Chr XII from 988425-990437, Verified ORF, "Cytoplasmic protein of unknown function; ubiquitinated protein with similarity to the human ring finger motif protein, RNF10; predicted to encode a DNA-3-methyladenine glycosidase II that c [SGD_S-cerevisiae_na_05-08-2009_con_reversed.fasta]
  • Ylr427wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • YLR427W [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • DNA-3-methyladenine glycosidase II that catalyzes of the hydrolysis of alkylated DNA; Mag2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • MAG2 SGDID:S000004419, Chr XII from 988425-990437, Verified ORF, "Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in re [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta]
  • MAG2 SGDID:S000004419, Chr XII from 988425-990437, Verified ORF, "Cytoplasmic protein of unknown function, predicted by computational analysis of interaction data to encode a DNA-3-methyladenine glycosidase II that catalyzes the hydrolysis of alkylated DNA" [yeast-bovrabprots.fasta]
  • MAG2 SGDID:S000004419, Chr XII from 988425-990437, Verified ORF, "Cytoplasmic protein of unknown function; ubiquitinated protein with similarity to the human ring finger motif protein, RNF10; predicted to encode a DNA-3-methyladenine glycosidase II that catalyzes hydrolysis of alkylated DNA" [scerevisihumanrev.fasta]
  • [chemostatdb.fasta]
  • MAG2 SGDID:S000004419, Chr XII from 988425-990437, Verified ORF, "Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1" [SGDyeast.20101221.fasta]
  • RING-finger protein MAG2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MAG2 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • MAG2 SGDID:S000004419, Chr XII from 988428-990440, Genome Release 64-1-1, Verified ORF, "Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1" [yeast-030211-contam.fasta]
  • MAG2 SGDID:S000004419, Chr XII from 988428-990440, Genome Release 64-2-1, Verified ORF, "Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1" [20141208_orf_trans.fasta]
  • YLR427W SGDID:S000004419, Chr XII from 988428-990440, Genome Release 64-1-1, Verified ORF, "Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 670 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: DNA dealkylation involved in DNA repair [RCALink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEPDMQKKA SGGSGGSEMD TLNATSNSSK QGVSNNKRNP VSKKKPGNKV SDGRDNAHNY  60
   61 HGEGRRKSSK QQRSRTPYKE TSTRINDQDI DLSIQEEILG GNFKLRGRKT QVSINHLLNF 120
  121 QLPEVEREKS RSSSSKKSNR RRDEHVHLHG DTFVNVNYRL LVDDRFDYPE QNCNPNVPVD 180
  181 QEKILRVIVP KGQNCSICLS EEPVAPRMVT CGHIFCLSCL LNFFSIEETV KNKETGYSKK 240
  241 KKYKECPLCG SIIGPKRVKP VLYEDDFDVT RLNQKPEPGA TVHLQLMCKP HGSLLPLPVA 300
  301 LHLDPLKCGN FPPANLGSIK HYAHIMKCGV SYSLELYQKD IVAIQEQYEI DKAIYNDSGK 360
  361 FVKQSIENIN DQISTLLAAT TDLSPLSNDI NNGLDNFHFD DDLLTKYDDS SAYFFYQTLV 420
  421 ASSTKYFLSP LDVKILLTIF HYYSKFPESI ETTVENIHYD TVVTEQLIRR YKYIGHLPIG 480
  481 TEIALLDLDW RKIPFLPKEI YEQFAHELKQ RRRKFTMKKQ KEDKEKKLYE KRLEQEHAEF 540
  541 YRKENGNSLK FEDSVQMATH YESIVSSSIP LNSLGISMLG PPTNSCSTPQ KQAPSHTKRT 600
  601 IWGTSIAVTE DEKASKENKE FQDMLLQRIR QEDSSDVTDS TDSPPTSNGK RGRKKKGKVM 660
  661 LFSSNHQALG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) AIM46 ARE1 CDC33 FET4 FUN12 GRS1 HAS1 IMD2 IMD3 IMD4 KRE33 KRI1 MAG2 MGM101 MSC3 NOC2 NOP12 NOP4 NPL3 OYE2 PDC6 RPF2 RRP12 TIF4631 TIF4632 UTP22

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TOR2 No Comments Reinke A, et al. (2004)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen DMC1 MAG2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MAG2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] MSA 2.121992 View MSA. No confident structure predictions are available.
    2 View Details [149..276] PSI-BLAST 4.221849 bard1 RING domain
    3 View Details [277..314] PSI-BLAST 2.09691 Nuclear factor XNF7
    4 View Details [315..493] MSA 5.279997 View MSA. No confident structure predictions are available.
    5 View Details [494..670] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.768717508465717 bayes_pls_golite062009
  • protein binding
    		•  0.38968855779244 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle