Protein Overview: REH1

General Information:
Name(s) found:	REH1 / YLR387C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|74644977\|sp\|Q06709.1\|REH1_YEAST RecName: Full=Zinc finger protein REH1; AltName: Full=REI1-homolog 1 [NCBI NR] gi\|6323419\|ref\|NP_013491.1\| Protein of unknown function, similar to Rei1p but not involved in bud growth; contains dispersed C2H2 zinc finger domains; Reh1p [Saccharomyces cerevisiae] [NCBI NR] gi\|609432\|gb\|AAB67280.1\| Ylr387cp [Saccharomyces cerevisiae] [NCBI NR] gi\|51012917\|gb\|AAT92752.1\| YLR387C [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S51474 hypothetical protein YLR387c - yeast (Saccharomyces cerevisiae) [NCBI NR] Zinc finger protein REH1 OS=Saccharomyces cerevisiae GN=REH1 PE=1 SV=1 [Swiss-Prot] REH1 Protein of unknown function, similar to Rei1p but not involved in bud growth [mips] Cytoplasmic 60S subunit biogenesis factor, associates with pre-60S particles; similar to Rei1p and shares partially redundant function in cytoplasmic 60S subunit maturation; contains dispersed C2H2 zinc finger domains [SGD] YLR387C, Chr XII from 896374-897672, reverse complement [yeast_orfs2] Chr XII from 896374-897672, reverse complement [yeastorf3.fasta] Chr XII from 897672-896374, reverse complement [yeastorf5.fasta] >Q06709 (Q06709) Chromosome XII COSMID L3502 (YLR387CP) [4932.FASTACCERV.txt] YLR387C SGDID:S0004379, Chr XII from 897672-896374, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] REH1 SGDID:S0004379, Chr XII from 897672-896374, reverse complement, Verified ORF [10112005cervSGD.fasta] Protein of unknown function, similar to Rei1p but not involved in bud growth; contains dispersed C2H2 zinc finger domains [Saccharomyces cerevisiae]gi\|51012917\|gb\|AAT92752.1\| YLR387C [Saccharomyces cerevisiae]gi\|1077339\|pir\|\|S51474 hypothetical protein [nrdb_11152004_Chlamydomonas] (Q06709) Ylr387cp (YLR387C) [cerv4932.FASTAC] REH1 SGDID:S000004379, Chr XII from 897672-896374, reverse complement, Verified ORF, "Protein of unknown function, similar to Rei1p but not involved in bud growth; contains dispersed C2H2 zinc finger domains" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YLR387C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Ylr387cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein of unknown function, similar to Rei1p but not involved in bud growth; contains dispersed C2H2 zinc finger domains; Reh1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] REH1 SGDID:S000004379, Chr XII from 897672-896374, reverse complement, Verified ORF, "Cytoplasmic 60S subunit biogenesis factor, associates with pre-60S particles; similar to Rei1p and shares partially redundant function in cytoplasmic 60S subunit maturat [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta] [chemostatdb.fasta] REH1 SGDID:S000004379, Chr XII from 897672-896374, reverse complement, Verified ORF, "Cytoplasmic 60S subunit biogenesis factor, associates with pre-60S particles; similar to Rei1p and shares partially redundant function in cytoplasmic 60S subunit maturation; contains dispersed C2H2 zinc finger domains" [SGDyeast.20101221.fasta] Zinc finger protein REH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=REH1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] REH1 SGDID:S000004379, Chr XII from 897672-896374, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic 60S subunit biogenesis factor, associates with pre-60S particles; similar to Rei1p and shares partially redundant function in cytoplasmic 60S subunit maturation; contains dispersed C2H2 zinc finger domains" [yeast-030211-contam.fasta] REH1 SGDID:S000004379, Chr XII from 897672-896374, Genome Release 64-2-1, reverse complement, Verified ORF, "Cytoplasmic 60S subunit biogenesis factor; associates with pre-60S particles; similar to Rei1p and shares partially redundant function in cytoplasmic 60S subunit maturation; contains dispersed C2H2 zinc finger domains" [20141208_orf_trans.fasta] YLR387C SGDID:S000004379, Chr XII from 897672-896374, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic 60S subunit biogenesis factor, associates with pre-60S particles; similar to Rei1p and shares partially redundant function in cytoplasmic 60S subunit maturation; contains dispersed C2H2 zinc finger domains" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] Cytoplasmic 60S subunit biogenesis factor REH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=REH1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Saccharomyces cerevisiae
Length:	432 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	biological_process [ND] [NOT]budding cell bud growth [IGI]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTFFTCNC CVIQFKTSDL QRYHMKTEWH RYNLKRRIAN LPPIGAEQFA EKLQISEKEQ  60
   61 AENQVDEFGF PVLKPVMNQS NALPQKQKKP IKSKRGRKVG TNLLKRKDRD IAKEKQNRSV 120
  121 SPSGSISSQL SNLTVGTENT NTDYGEDTVS EYGFTSDSNY EYATSDEELD IADKPSDKEN 180
  181 EKITITECIY CGKDNKEVER NVKHMFSEHG LFIPERSYLI DLNGLLEFLI KMIVIDHNCL 240
  241 CCNFHGSGLE SIRAHMASKR HCRLPYETKE ERQLFAPFYD FTYDDHSISK NLQNDRAITS 300
  301 KLSSVYGAKN DEEDGEVDIT LVSSENDINA NYTTVSIDES GLELTLPTGA RLGHRAGQRY 360
  361 YRQNLPSQPN PNESRRTITA ADRRMVSGVT EKQYKKGMKK MQQLEKNAIN TQIRREIKRV 420
  421 NFQTHYRDEL LQ

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		CAB3 CHD1 CKA1 CKA2 CKB1 CKB2 ELF1 HOT1 MSC3 NRG1 PGA2 REH1 RIM13 VHS3 YLR407W
View Details	Qiu et al. (2008)		AST2 GCN4 MON1 REH1 RPS30B, RPS30A YPL199C

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	REH1	HTZ1	2	Unpublished Fields Lab Data
View Screen	REH1	SMA1	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	REH1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..96]	PSI-BLAST	27.0	Designed zinc finger protein
2	View Details	[97..289]	MSA	10.533996	View MSA. No confident structure predictions are available.
3	View Details	[290..432]	deduced	N/A	No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
binding	2.36961042761402	bayes_pls_golite062009
DNA binding	1.83298509797997	bayes_pls_golite062009
nucleic acid binding	1.81905872620454	bayes_pls_golite062009
transcription regulator activity	1.79634171647159	bayes_pls_golite062009
RNA binding	1.69160965456631	bayes_pls_golite062009
transcription factor activity	0.972881822816115	bayes_pls_golite062009
transcription activator activity	0.953363449552372	bayes_pls_golite062009
protein binding	0.852654490075478	bayes_pls_golite062009
sequence-specific DNA binding	0.246568450747506	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.095249486073484	bayes_pls_golite062009
chromatin binding	0.0383915131562336	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2