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Protein Overview: OXP1

General Information:
Name(s) found: OXP1 / YKL215C [SGD]
Description(s) found:
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  • gi|6322634|ref|NP_012707.1| Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; Ykl215cp [Saccharomyces cerevisiae] [NCBI NR]
  • gi|549754|sp|P28273.2|YKV5_YEAST RecName: Full=Uncharacterized protein YKL215C [NCBI NR]
  • pir||S38058 hypothetical protein YKL215c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|486385|emb|CAA82060.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|473135|emb|CAA53558.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • Uncharacterized protein YKL215C OS=Saccharomyces cerevisiae GN=YKL215C PE=1 SV=2 [Swiss-Prot]
  • Protein of unknown function localised to cytoplasm [mips]
  • 5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm [SGD]
  • YKL215C, Chr XI from 26828-30688, reverse complement [yeast_orfs2]
  • Chr XI from 26828-30688, reverse complement [yeastorf3.fasta]
  • Chr XI from 30688-26828, reverse complement [yeastorf5.fasta]
  • (P28273) Hypothetical 140.4 kDa protein in URA1-DOA1 intergenic region [4932.FASTACCERV.txt]
  • YKL215C SGDID:S0001698, Chr XI from 30688-26828, reverse complement, Uncharacterized ORF [yeastflysequest.fasta]
  • Ykl215cp [Saccharomyces cerevisiae]gi|473135|emb|CAA53558.1| unnamed protein product [Saccharomyces cerevisiae]gi|486385|emb|CAA82060.1| unnamed protein product [Saccharomyces cerevisiae]gi|539224|pir||S38058 hypothetical protein YKL215c - yeast (Sacch [nrdb_11152004_Chlamydomonas]
  • YKL215C SGDID:S000001698, Chr XI from 30688-26828, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Uncharacterized protein YKL215C [nr-271106-contam.fasta]
  • Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; Ykl215cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • OXP1 SGDID:S000001698, Chr XI from 30687-26827, Genome Release 64-1-1, reverse complement, Verified ORF, "5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" [yeast-030211-contam.fasta]
  • OXP1 SGDID:S000001698, Chr XI from 30687-26827, Genome Release 64-2-1, reverse complement, Verified ORF, "5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress" [20141208_orf_trans.fasta]
  • TR7734|c0_g1_i1|g.5371 ORF TR7734|c0_g1_i1|g.5371 TR7734|c0_g1_i1|m.5371 type:complete len:1287 (+) TR7734|c0_g1_i1:97-3957(+) [Y12_S_cerevisiae-Sep2015-contam.fasta]
  • YKL215C SGDID:S000001698, Chr XI from 30687-26827, Genome Release 64-1-1, reverse complement, Verified ORF, "5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
  • ID=asmbl_6593|g.4237 ORF ID=asmbl_6593|g.4237 ID=asmbl_6593|m.4237 type:complete len:1287 (+) ID=asmbl_6593:96-3956(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 1286 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKGNIRIAI DKGGTFTDCV GNIGTGKQEH DTVIKLLSVD PKNYPDAPLE GIRRLLEVLE  60
   61 HKTIPRGIPL DISNVRSLRM GTTLATNCAL ERNGERCAFI TTKGFKDSLL IGDQTRPDIF 120
  121 NLNIKKVVPL YDTVVEIDER VTLEDFSEDP YFTKSSPNEQ EGILEGNSGE MVRVIKKPDE 180
  181 SSVRSILKVL YASGIKSIAI AFLHSYTFPD HERIVGNIAR EIGFSHVSLS SEVSPMIKFL 240
  241 PRAHSSVADA YLTPVIKKYL NSISAGLSHA EDTHIQFMQS DGGLVDGGKF SGLKSILSGP 300
  301 AGGVIGYSST CYDKNNNIPL IGFDMGGTST DVSRYGDGRL EHVFETVTAG IIIQSPQLDI 360
  361 HTVAAGGSSI LSWKNGLFRV GPDSAAADPG PAAYRKGGPL TITDANLFLG RLVPEFFPKI 420
  421 FGPNEDESLD LETTTLKFRE LTDVINKDLN SNLTMEEVAY GFIKVANECM ARPVRAITEA 480
  481 KGHVVSQHRL VSFGGAGGQH AIAVADSLGI DTVLIHRYSS ILSAYGIFLA DVIEENQEPC 540
  541 SFILGEPETI LKVKKRFLEL SKNSIKNLLS QSFSREDIVL ERYLNLRYEG TETSLMILQK 600
  601 YDDQWNFREW FSEAHKKEFG FSFDDKRIII DDIRIRAIGK SGVRKEKTVD EQLIEISHFK 660
  661 KADVSKDASF TQKAYFDNKW VDTAVFKIDD LPAGTIIEGP AILADGTQTN IILPNSQATI 720
  721 LNSHIFIKIN QKAAKTLSKS GYELDIDPIL LSIFSHRFMD IALQMGTQLR KTSVSTNVKE 780
  781 RLDFSCALFD SKGNLVANAP HVPVHLGSMS TCISAQAKLW EGKLKPGDVL ITNHPDIGGT 840
  841 HLPDITVITP SFSSTGELIF YVASRAHHAD IGGILPGSVP PNSKELYEEG TAIYSELVVK 900
  901 EGIFQEELIY KLFVEDPGKY PGCSGSRRFS DNISDLKAQV AANTKGIQLI GSLTKEYDLA 960
  961 TILKYMAAIQ TNASESIKKM LAKMVEHFGT TKFSGEDRLD DGSLIKLQVI IRPEKEEYIF1020
 1021 NFDGTSPQVY GNLNAPEAIT NSAILYCLRC LVGEDIPLNQ GCLKPLTIKI PAGSLLSPRS1080
 1081 GAAVVGGNVL TSQRVTDVIL KTFNVMADSQ GDCNNFTFGT GGNSGNKTDK QIKGFGYYET1140
 1141 ICGGSGAGAD SWRGSGWNGS DAVHTNMTNT RMTDTEVFER RYPVLLKEFS IRRGSGGKGK1200
 1201 YTGGNGVVRD VQFRKAVTAS ILSERRVIGP HGIKGGQDGS RGENLWVRHS TGALINVGGK1260
 1261 NTIYAQPGDR FIIKTPGGGG FGQYKD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) APD1 OXP1 SPC98 YPL199C
    View Details Ho Y, et al. (2002) HSP104 OXP1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run RLF2 identification data - first search in cascade Green EM, et al (2005)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #34 Asynchronous SPB prep Keck JM, et al. (2011)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #02 Alpha Factor Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data OXP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..664] Pfam 1000.0 Hydantoinase/oxoprolinase No confident structure predictions are available.
    2 View Details [665..741] deduced N/A Confident ab initio structure predictions are available.
    3 View Details [742..1286] Pfam 1000.0 Hydantoinase B/oxoprolinase No confident structure predictions are available.
    4 View Details [878..957] deduced N/A No confident structure predictions are available.
    5 View Details [958..1119] MSA 1.177994 View MSA. No confident structure predictions are available.
    6 View Details [1120..1181] MSA 1.176993 View MSA. No confident structure predictions are available.
    7 View Details [1182..1286] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • carbohydrate kinase activity
    		•  1.59015355865021 bayes_pls_golite062009
  • kinase activity
    		•  0.936112985314189 bayes_pls_golite062009
  • binding
    		•  0.874703945174078 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.839311348589465 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.644753323874683 bayes_pls_golite062009
  • hexokinase activity
    		•  0.570508441475985 bayes_pls_golite062009
  • hydrolase activity
    		•  0.440062766964367 bayes_pls_golite062009
  • catalytic activity
    		•  0.308539563780047 bayes_pls_golite062009
  • transferase activity
    		•  0.0223144423385645 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle