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Protein Overview: EUG1

General Information:
Name(s) found: EUG1 / YDR518W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 517 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: protein folding [IGILink to PubMed article]
    Molecular Function: protein disulfide isomerase activity [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article][ISSLink to PubMed article]
    protein disulfide oxidoreductase activity [IDALink to PubMed article][IGILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVTTRFISA IVSFCLFASF TLAENSARAT PGSDLLVLTE KKFKSFIESH PLVLVEFFAP  60
   61 WCLHSQILRP HLEEAASILK EHNVPVVQID CEANSMVCLQ QTINTYPTLK IFKNGRIFDG 120
  121 QVYRGVKITD EITQYMIQLY EASVIYLNSE DEIQPYLENA TLPVVINRGL TGLNETYQEV 180
  181 ALDLAEDYVF LSLLDSEDKS LSIHLPNTTE PILFDGNVDS LVGNSVALTQ WLKVVILPYF 240
  241 TDIEPDLFPK YISSNLPLAY FFYTSEEELE DYTDLFTQLG KENRGQINFI ALNSTMFPHH 300
  301 VRFLNMREQF PLFAIHNMIN NLKYGLPQLP EEEYAKLEKP QPLDRDMIVQ LVKDYREGTA 360
  361 KPIVKSEEIP KEQKSNVYKI VGKTHDDIVH DDDKDVLVKY YATWCIHSKR FAPIYEEIAN 420
  421 VLASDESVRD KILIAEVDSG ANDILSFPVT GYPTIALYPA GNNSKPIIFN KIRNLEDVFE 480
  481 FIKESGTHHI DGQAIYDKLH QAKDSEVSTE DTVHDEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen EUG1 RPC53 2 Unpublished Fields Lab Data
    View Screen EUG1 CBS2 2 Unpublished Fields Lab Data
    View Screen EUG1 WHI2 2 Unpublished Fields Lab Data
    View Screen EUG1 SCD6 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..146] PSI-BLAST 140.29073 Protein disulfide isomerase, PDI
    2 View Details [147..255] PSI-BLAST 7.39794 Protein disulfide isomerase, PDI
    3 View Details [256..330] MSA 1.156996 View MSA. Confident ab initio structure predictions are available.
    4 View Details [331..517] PSI-BLAST 70.70927 Thioredoxin


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle