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Protein Overview: RAD28

General Information:
Name(s) found: RAD28 / YDR030C [SGD]
Description(s) found:
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  • gi|74676500|sp|Q12021.1|RAD28_YEAST RecName: Full=Radiation-sensitive protein 28 [NCBI NR]
  • gi|642302|emb|CAA87809.1| unknown [Saccharomyces cerevisiae] [NCBI NR]
  • gi|6320233|ref|NP_010313.1| Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSA protein; Rad28p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1431468|emb|CAA98852.1| RAD28 [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S50937 hypothetical protein YDR030c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Radiation-sensitive protein 28 OS=Saccharomyces cerevisiae GN=RAD28 PE=2 SV=1 [Swiss-Prot]
  • RAD28 Protein involved in the same pathway as Rad26p, has beta-transducin (WD-40) repeats [mips]
  • Protein involved in DNA repair, related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair [SGD]
  • RAD28, Chr IV from 501748-503268, reverse complement [yeast_orfs2]
  • Chr IV from 501748-503268, reverse complement [yeastorf3.fasta]
  • Chr IV from 503268-501748, reverse complement [yeastorf5.fasta]
  • >Q12021 (Q12021) Chromosome IV reading frame ORF YDR030C [4932.FASTACCERV.txt]
  • RAD28 SGDID:S0002437, Chr IV from 503269-501749, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Protein involved in transcription-coupled repair nucleotide exicision repair of UV-induced DNA lesions; homolog of human CSA protein [Saccharomyces cerevisiae]gi|1431468|emb|CAA98852.1| RAD28 [Saccharomyces cerevisiae]gi|642302|emb|CAA87809.1| unknown [ [nrdb_11152004_Chlamydomonas]
  • (Q12021) RAD28 protein (Hypothetical protein) [cerv4932.FASTAC]
  • RAD28 SGDID:S000002437, Chr IV from 503269-501749, reverse complement, Verified ORF, "Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSA protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • RAD28 SGDID:S000002437, Chr IV from 503270-501750, reverse complement, Verified ORF, "Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSA protein" [yeast-contam.fasta]
  • RAD28 SGDID:S000002437, Chr IV from 503271-501751, reverse complement, Verified ORF, "Protein involved in DNA repair, related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • RAD28 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSA protein; Rad28p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Radiation-sensitive protein 28 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD28 PE=2 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • RAD28 SGDID:S000002437, Chr IV from 503273-501753, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in DNA repair, related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair" [yeast-030211-contam.fasta]
  • Radiation-sensitive protein 28 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD28 PE=4 SV=1 [YEAST.fasta.20131015]
  • RAD28 SGDID:S000002437, Chr IV from 503273-501753, Genome Release 64-2-1, reverse complement, Verified ORF, "Protein involved in DNA repair; related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair" [20141208_orf_trans.fasta]
  • YDR030C SGDID:S000002437, Chr IV from 503273-501753, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in DNA repair, related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
  • Radiation-sensitive protein 28 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD28 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Saccharomyces cerevisiae
    Length: 506 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    Biological Process: DNA repair [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPFLEFRVG NISLNEFYRR TIQSEFERIL EDPLSNMKNY RFSKQSNYST KEKTPLSIGV  60
   61 NCLDIDDTGQ VLLGGGDDGS LSIWGLDESL HRNDEGEQEL INKRLNYIKR QPHQSDDEPA 120
  121 QIMGYKNKRT RINDNNTMRL VHSFQTQRNK YRMYRQSSAA VPVQRSHISN KTDSPIGFSE 180
  181 TLSETDSEAS ISHHKYGITT LKWYKADNGM FFTGSNDKTV KIWDTNRFEA VQDINLGYKI 240
  241 NQIDNNVVDD SSLLVVASED YYPRLIDLRT MNSGVTALGM GNQTRMQSEI LCCKFNPVRE 300
  301 QIIACGDMEG GVKLWDLRMR NRLYSELKRN KNRFKTINND DNDDQSDVYF SSNQSKAHLR 360
  361 CCSDIVWNSE GSELCSVGMD GKLNVWRPFT EILQPEGLAS YSQLGTQDLS RIKYKKRVSR 420
  421 RLLWFDKFLL CITDNGEVEI YNTEEKKLWN KLEYPMVNQV KKNQASHCQF SSMIVQTNIM 480
  481 NSVGLKLFFG TNNNTVSDGG SIFECS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) CCT2 CCT6 DUN1 RAD28 TCP1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..317] PSI-BLAST 25.69897 Groucho/tle1, C-terminal domain
    2 View Details [318..405] PSI-BLAST 70.30103 beta1-subunit of the signal-transducing G protein heterotrimer
    3 View Details [406..506] MSA 2.634995 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle