YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|153997226, gi...
Organism:	Yersinia pestis CA88-4125
Length:	215 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|153997226, gi....

Description	E-value	Query Range	Subject Range
THIE_YERPS - Thiamine-phosphate synthase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=thiE PE=3 ... THIE_YERPS - Thiamine-phosphate synthase OS=Yersinia pseudotuberculosis GN=thiE PE=3 SV=1 THIE_YERP3 - Thiamine-phosphate synthase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=thiE P...	8.0E-40	[1..215]	[1..215]
gi\|169749138, gi... - gi\|170022604\|ref\|YP_001719109.1\| thiamine-phosphate pyrophosphorylase [Yersinia pseudotuberculosis Y... gi\|117675270, gi... - gi\|77631240\|ref\|ZP_00793826.1\| COG0352: Thiamine monophosphate synthase [Yersinia pseudotuberculosis... gi\|186893646, gi... - gi\|186893646\|ref\|YP_001870758.1\| thiamine-phosphate pyrophosphorylase [Yersinia pseudotuberculosis P...	2.0E-39	[1..215]	[10..224]
gi\|145212680, gi... - gi\|145600984\|ref\|YP_001165060.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis Pestoides F],... gi\|77633257, gi\|... - gi\|77633257\|ref\|ZP_00795398.1\| COG0352: Thiamine monophosphate synthase [Yersinia pestis Angola], gi... gi\|166204422, gi... - gi\|166214418\|ref\|ZP_02240453.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis biovar Antiqua... gi\|167048208, gi... - gi\|167402428\|ref\|ZP_02307888.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis biovar Antiqua... gi\|165919668, gi... - gi\|165928329\|ref\|ZP_02224161.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis biovar Orienta... gi\|166012051, gi... - gi\|166012051\|ref\|ZP_02232949.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis biovar Antiqua... gi\|167470151 - gi\|167470151\|ref\|ZP_02334855.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis FV-1] gi\|166957138, gi... - gi\|167422927\|ref\|ZP_02314680.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis biovar Orienta... gi\|108810392, gi... - gi\|108810392\|ref\|YP_646159.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis Nepal516], gi\|10... gi\|167426807, gi... - gi\|167426807\|ref\|ZP_02318560.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis biovar Mediaev... gi\|108809603, gi... - gi\|108809603\|ref\|YP_653519.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis Antiqua], gi\|108... gi\|165938137, gi... - gi\|89103191\|ref\|ZP_01175780.1\| COG0352: Thiamine monophosphate synthase [Yersinia pestis biovar Orie...	3.0E-39	[1..215]	[10..224]
gi\|45442857, gi\|... - gi\|45442857\|ref\|NP_994396.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis biovar Microtus s... gi\|22124405, gi\|... - gi\|22124405\|ref\|NP_667828.1\| thiamine-phosphate pyrophosphorylase [Yersinia pestis KIM], gi\|21957188...	5.0E-39	[1..215]	[15..229]
THIE_CALS8 - Thiamine-phosphate synthase OS=Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) G...	6.0E-38	[1..212]	[1..219]
gi\|94425984, gi\|... - gi\|94501851\|ref\|ZP_01308362.1\| hypothetical protein RED65_02128 [Oceanobacter sp. RED65], gi\|9442598...	2.0E-37	[6..207]	[290..491]
THIE_BACC1 - Thiamine-phosphate synthase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=thiE PE=3 SV=1	2.0E-37	[1..208]	[1..217]
THIE_PHOLL - Thiamine-phosphate pyrophosphorylase OS=Photorhabdus luminescens subsp. laumondii GN=thiE PE=3 SV=1 THIE_PHOLL - Thiamine-phosphate synthase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105...	2.0E-37	[5..207]	[8..210]
gi\|78044820, gi\|... - gi\|78044820\|ref\|YP_359600.1\| thiamine-phosphate pyrophosphorylase [Carboxydothermus hydrogenoformans...	2.0E-37	[8..210]	[154..363]
gi\|48891748, gi\|... - gi\|71674938\|ref\|ZP_00672684.1\| Thiamine monophosphate synthase [Trichodesmium erythraeum IMS101], gi...	3.0E-37	[11..209]	[147..347]

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Predicted Domain #1

Region A:
Residues: [1-215]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPGFPSTE QRLGLYPVVD SLLWIERLLA AGVTTLQLRI KNADDAQVEQ DIVAAIELGK  60
   61 RYQARLFIND YWQLAVKHGA YGVHLGQEDL EAADLAAIQQ AGLRLGISTH DEHELAVAKT 120
  121 LRPSYIALGH IFPTQTKQMP SSPQGLASLS RQVKNTPDYP TVAIGGISIE RVPHVLATGV 180
  181 GSVAVVSAIT LASDWQRATA QLLHLIEGKE LADEK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.69897
Match:	1g4tA
Description:	Thiamin phosphate synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
thiamin-phosphate diphosphorylase activity	6.04450222340788	bayes_pls_golite062009
catalytic activity	2.31352397210218	bayes_pls_golite062009
phosphomethylpyrimidine kinase activity	2.16632642989285	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	1.16976945211093	bayes_pls_golite062009
transferase activity	1.16478613213801	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	0.63318404518052	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: