Bait Protein: | MLP2 |
Organism: | Saccharomyces cerevisiae |
Publication: | Keck JM, Jones MH, Wong CC, Binkley J, Chen D, Jaspersen SL, Holinger EP, Xu T, Niepel M, Rout MP, Vogel J, Sidow A, Yates JR, Winey M., A Cell Cycle Phosphoproteome of the Yeast Centrosome, Science 24 June 2011: 1557-1561. |
Comments: | #32 Asynchronous Prep-No Phosphopeptide enrichment |
Raw Data: |
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FILTERED Run Results:
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Hit Protein | Protein Desc | Sequence Count | Spectrum Count | Sequence Coverage | NSAF | Mol. Wt. | |
[ |
SPC42 | Central plaque component of spindle pole body (SPB); involved in SPB duplication, may facilitate att... | 59 | 87 | 74.9% | 0.0271 | 42271 |
[ |
CDC31 | Calcium-binding component of the spindle pole body (SPB) half-bridge, required for SPB duplication i... | 29 | 41 | 72.0% | 0.0288 | 18751 |
[ |
SPC29 | Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inn... | 29 | 50 | 60.1% | 0.0224 | 29280 |
[ |
SPC110 | Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nu... | 131 | 350 | 55.5% | 0.042 | 111782 |
[ |
YIL002W-A | Putative protein of unknown function; identified by expression profiling and mass spectrometry | 21 | 37 | 53.6% | 0.0607 | 7729 |
[ |
CNM67 | Component of the spindle pole body outer plaque; required for spindle orientation and mitotic nuclea... | 68 | 111 | 53.2% | 0.0216 | 67400 |
[ |
MLP2 | Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the... | 188 | 401 | 49.8% | 0.0271 | 195140 |
[ |
CMD1 | Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, act... | 13 | 17 | 40.8% | 0.0131 | 16135 |
[ |
BUB2 | Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spi... | 23 | 51 | 38.6% | 0.0189 | 35028 |
[ |
NOP10 | Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are ... | 2 | 2 | 36.2% | 0.00391 | 6636 |
[ |
BFA1 | Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pa... | 32 | 64 | 35.4% | 0.0126 | 66087 |
[ |
NUD1 | Component of the spindle pole body outer plaque, required for exit from mitosis | 95 | 261 | 34.3% | 0.0347 | 94104 |
[ |
CDC14 | Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR ... | 31 | 62 | 32.1% | 0.0127 | 61907 |
[ |
RPP2A | Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction... | 4 | 4 | 32.1% | 0.00427 | 10746 |
[ |
CDC19 | Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvat... | 21 | 44 | 30.0% | 0.00997 | 54545 |
[ |
RPP1B | Ribosomal protein P1 beta, component of the ribosomal stalk, which is involved in interaction of tra... | 4 | 4 | 28.3% | 0.00427 | 10668 |
[ |
GPM1 | Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycer... | 9 | 11 | 27.5% | 0.00504 | 27609 |
[ |
RPP0 | Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphoryl... | 15 | 35 | 26.9% | 0.0127 | 33717 |
[ |
NBP1 | Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuc... | 7 | 8 | 26.3% | 0.00284 | 37354 |
[ |
HTB2 | Histone H2B, core histone protein required for chromatin assembly and chromosome function; nearly id... | 7 | 12 | 26.0% | 0.0104 | 14237 |
[ |
HTB1 | Histone H2B, core histone protein required for chromatin assembly and chromosome function; nearly id... | 7 | 12 | 26.0% | 0.0104 | 14252 |
[ |
PDC1 | Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates... | 26 | 40 | 25.9% | 0.00805 | 61495 |
[ |
TUB4 | Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of th... | 15 | 25 | 25.2% | 0.00599 | 52628 |
[ |
NOP1 | Nucleolar protein, component of the small subunit processome complex, which is required for processi... | 19 | 38 | 24.8% | 0.0132 | 34465 |
[ |
TSA1 | Thioredoxin peroxidase, acts as both a ribosome-associated and free cytoplasmic antioxidant; self-as... | 5 | 5 | 24.0% | 0.00289 | 21590 |
[ |
PMA1 | Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plas... | 35 | 58 | 23.5% | 0.00716 | 99619 |
[ |
RPP1A | Ribosomal stalk protein P1 alpha, involved in the interaction between translational elongation facto... | 2 | 2 | 22.6% | 0.00214 | 10908 |
[ |
TEF1, TEF2 | Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction ... | 17 | 23 | 22.3% | 0.00569 | 50033 |
[ |
BBP1 | Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periph... | 10 | 11 | 22.1% | 0.00324 | 45384 |
[ |
ENO2 | Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosp... | 12 | 16 | 19.0% | 0.00415 | 46914 |
[ |
EGD1 | Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, ass... | 2 | 2 | 18.5% | 0.00144 | 17020 |
[ |
MRH1 | Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the aut... | 10 | 12 | 18.1% | 0.00425 | 36191 |
[ |
MPS2 | Essential membrane protein localized at the nuclear envelope and spindle pole body (SPB), required f... | 12 | 22 | 17.8% | 0.00644 | 44585 |
[ |
PSA1 | GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from ... | 6 | 7 | 17.5% | 0.0022 | 39566 |
[ |
SAM2 | S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom ... | 6 | 7 | 16.9% | 0.00206 | 42256 |
[ |
HSL7 | Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization ... | 15 | 19 | 16.8% | 0.0026 | 95153 |
[ |
YRA1 | RNA binding protein required for export of poly(A)+ mRNA from the nucleus; proposed to couple mRNA e... | 5 | 8 | 16.8% | 0.00401 | 24956 |
[ |
ASC1 | G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 th... | 6 | 6 | 16.6% | 0.00213 | 34805 |
[ |
NOP56 | Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that ... | 9 | 14 | 16.3% | 0.00315 | 56864 |
[ |
HTA1 | Histone H2A, core histone protein required for chromatin assembly and chromosome function; one of tw... | 4 | 4 | 15.2% | 0.00343 | 13989 |
[ |
HTA2 | Histone H2A, core histone protein required for chromatin assembly and chromosome function; one of tw... | 4 | 4 | 15.2% | 0.00343 | 13989 |
[ |
RHO1 | GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell pol... | 2 | 2 | 14.4% | 0.00108 | 23152 |
[ |
KAR1 | Essential protein involved in karyogamy during mating and in spindle pole body duplication during mi... | 5 | 6 | 14.3% | 0.00157 | 50653 |
[ |
HSP26 | Small heat shock protein (sHSP) with chaperone activity; forms hollow, sphere-shaped oligomers that ... | 2 | 2 | 14.0% | 0.00106 | 23880 |
[ |
SAM1 | S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom ... | 6 | 7 | 13.6% | 0.00208 | 41818 |
[ |
APT1 | Adenine phosphoribosyltransferase, catalyzes the formation of AMP from adenine and 5-phosphoribosylp... | 2 | 3 | 13.4% | 0.00182 | 20587 |
[ |
NOP58 | Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the ... | 13 | 16 | 13.3% | 0.00355 | 56956 |
[ |
VMA2 | Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), a... | 5 | 5 | 13.0% | 0.0011 | 57749 |
[ |
FPR3 | Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by cas... | 6 | 7 | 12.9% | 0.00193 | 46553 |
[ |
SPC72 | Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole bodies and links them... | 9 | 9 | 12.7% | 0.00164 | 72105 |
[ |
ADH1 | Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the red... | 4 | 4 | 12.6% | 0.0013 | 36849 |
[ |
EFT2, EFT1 | Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein s... | 14 | 16 | 12.5% | 0.00215 | 93289 |
[ |
ALD6 | Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; re... | 5 | 5 | 12.2% | 0.00113 | 54414 |
[ |
NSR1 | Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ri... | 4 | 4 | 12.1% | 0.00109 | 44535 |
[ |
YEF3 | Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes b... | 16 | 20 | 12.0% | 0.00217 | 115945 |
[ |
DBP3 | Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis | 6 | 9 | 11.9% | 0.00195 | 58827 |
[ |
PRS5 | 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleot... | 4 | 6 | 11.9% | 0.00137 | 53505 |
[ |
TUB2 | Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymeriz... | 7 | 7 | 11.4% | 0.00173 | 50923 |
[ |
PGK1 | 3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phospha... | 5 | 5 | 11.3% | 0.00136 | 44738 |
[ |
RPB5 | RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects tra... | 2 | 2 | 11.2% | 0.00105 | 25079 |
[ |
NDC1 | Nuclear envelope protein with multiple putative transmembrane domains, required for nuclear pore com... | 11 | 12 | 11.0% | 0.00208 | 74134 |
[ |
GSP1 | Ran GTPase, GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear orga... | 3 | 5 | 11.0% | 0.00259 | 24810 |
[ |
GSP2 | GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RN... | 3 | 5 | 10.9% | 0.00257 | 24991 |
[ |
CBR1 | Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutat... | 3 | 4 | 10.9% | 0.00141 | 36199 |
[ |
YGR027W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 18 | 20 | 10.8% | 0.00129 | 198656 |
[ |
YRO2 | Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphoryla... | 6 | 8 | 10.5% | 0.00263 | 38720 |
[ |
CYS3 | Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathw... | 4 | 5 | 10.4% | 0.00144 | 42542 |
[ |
WWM1 | WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that re... | 2 | 2 | 10.0% | 0.00107 | 22655 |
[ |
YDJ1 | Protein chaperone involved in regulation of the HSP90 and HSP70 functions; involved in protein trans... | 3 | 3 | 9.8% | 8.31E-4 | 44671 |
[ |
BUD21 | Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA; originally isolated... | 2 | 3 | 9.8% | 0.00159 | 24385 |
[ |
HXT7 | High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, e... | 8 | 8 | 9.5% | 0.00159 | 62735 |
[ |
RPA34 | RNA polymerase I subunit A34.5 | 2 | 2 | 9.4% | 9.72E-4 | 26875 |
[ |
CCW14 | Covalently linked cell wall glycoprotein, present in the inner layer of the cell wall | 2 | 2 | 9.2% | 9.52E-4 | 23268 |
[ |
SFI1 | Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the ... | 9 | 13 | 8.9% | 0.00156 | 112978 |
[ |
ILV5 | Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosy... | 4 | 4 | 8.6% | 0.00115 | 44368 |
[ |
HOM2 | Aspartic beta semi-aldehyde dehydrogenase, catalyzes the second step in the common pathway for methi... | 3 | 3 | 8.5% | 9.31E-4 | 39544 |
[ |
GAR1 | Protein component of the H/ACA snoRNP pseudouridylase complex, involved in the modification and clea... | 12 | 23 | 8.3% | 0.0127 | 21480 |
[ |
ARF2 | ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation ve... | 2 | 3 | 8.3% | 0.00188 | 20658 |
[ |
ARF1 | ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle form... | 2 | 3 | 8.3% | 0.00188 | 20529 |
[ |
PGI1 | Glycolytic enzyme phosphoglucose isomerase, catalyzes the interconversion of glucose-6-phosphate and... | 3 | 4 | 8.1% | 8.18E-4 | 61299 |
[ |
RBG1 | Member of the DRG family of GTP-binding proteins; associates with translating ribosomes; interacts w... | 2 | 2 | 8.1% | 6.14E-4 | 40701 |
[ |
POR1 | Mitochondrial porin (voltage-dependent anion channel), outer membrane protein required for the maint... | 2 | 2 | 8.1% | 8.0E-4 | 30428 |
[ |
SUP35 | Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a domi... | 4 | 4 | 7.9% | 6.61E-4 | 76551 |
[ |
SRO9 | Cytoplasmic RNA-binding protein that associates with translating ribosomes; involved in heme regulat... | 3 | 3 | 7.8% | 7.83E-4 | 48060 |
[ |
ACT1 | Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functio... | 4 | 6 | 7.7% | 0.00181 | 41690 |
[ |
YER160C | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 15 | 17 | 7.6% | 0.0011 | 198568 |
[ |
SBP1 | Putative RNA binding protein; involved in translational repression and found in cytoplasmic P bodies... | 2 | 2 | 7.5% | 7.71E-4 | 32990 |
[ |
YBR012W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 11 | 12 | 7.0% | 7.74E-4 | 198868 |
[ |
GAL2 | Galactose permease, required for utilization of galactose; also able to transport glucose | 5 | 5 | 6.6% | 9.87E-4 | 63626 |
[ |
HOM3 | Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in ... | 4 | 6 | 6.5% | 0.00129 | 58110 |
[ |
TIF1, TIF2 | Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPa... | 2 | 3 | 6.3% | 8.6E-4 | 44697 |
[ |
CDC5 | Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and ... | 4 | 5 | 6.2% | 8.03E-4 | 81031 |
[ |
NOP2 | Probable RNA m(5)C methyltransferase, essential for processing and maturation of 27S pre-rRNA and la... | 2 | 4 | 6.1% | 7.33E-4 | 69812 |
[ |
FBA1 | Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis; catalyzes conversio... | 3 | 4 | 6.1% | 0.00126 | 39621 |
[ |
FCY22 | Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function | 2 | 3 | 6.0% | 6.41E-4 | 57327 |
[ |
FCY2 | Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumula... | 2 | 3 | 6.0% | 6.38E-4 | 58201 |
[ |
MET6 | Cobalamin-independent methionine synthase, involved in methionine biosynthesis and regeneration; req... | 4 | 5 | 5.9% | 7.38E-4 | 85860 |
[ |
CKA2 | Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and ... | 2 | 2 | 5.9% | 6.68E-4 | 39404 |
[ |
SPC97 | Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the... | 6 | 6 | 5.8% | 8.26E-4 | 96825 |
[ |
KES1 | Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in neg... | 2 | 2 | 5.8% | 5.22E-4 | 49492 |
[ |
HSC82 | Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly identical with Hsp82p, a... | 4 | 4 | 5.7% | 6.43E-4 | 80900 |
[ |
HXT1 | Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2... | 5 | 5 | 5.6% | 9.94E-4 | 63261 |
[ |
HXT3 | Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low ... | 5 | 5 | 5.6% | 9.99E-4 | 62558 |
[ |
CUP5 | Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide bindi... | 2 | 2 | 5.6% | 0.00142 | 16351 |
[ |
HRR25 | Protein kinase involved in regulating diverse events including vesicular trafficking, DNA repair, an... | 2 | 3 | 5.5% | 6.88E-4 | 57340 |
[ |
RPT1 | One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation ... | 2 | 2 | 5.4% | 4.85E-4 | 51983 |
[ |
NAP1 | Protein that interacts with mitotic cyclin Clb2p; required for the regulation of microtubule dynamic... | 2 | 3 | 5.3% | 8.15E-4 | 47885 |
[ |
YHR020W | Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ... | 3 | 3 | 5.2% | 4.94E-4 | 77386 |
[ |
SPC98 | Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the... | 7 | 15 | 5.0% | 0.00201 | 98227 |
[ |
IPP1 | Cytoplasmic inorganic pyrophosphatase (PPase), homodimer that catalyzes the rapid exchange of oxygen... | 2 | 5 | 4.9% | 0.00197 | 32300 |
[ |
PRP43 | RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript... | 3 | 3 | 4.7% | 4.43E-4 | 87562 |
[ |
CYS4 | Cystathionine beta-synthase, catalyzes synthesis of cystathionine from serine and homocysteine, the ... | 2 | 2 | 4.7% | 4.47E-4 | 56022 |
[ |
HER2 | Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; ... | 2 | 2 | 4.7% | 4.88E-4 | 50919 |
[ |
ROK1 | ATP-dependent RNA helicase of the DEAD box family; required for 18S rRNA synthesis | 3 | 3 | 4.6% | 6.03E-4 | 63653 |
[ |
DBP2 | Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated m... | 3 | 3 | 4.6% | 6.22E-4 | 60999 |
[ |
GUS1 | Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; ... | 2 | 3 | 4.5% | 4.8E-4 | 80843 |
[ |
ERG11 | Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimeth... | 2 | 2 | 4.5% | 4.27E-4 | 60720 |
[ |
URA2 | Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes t... | 8 | 9 | 4.4% | 4.6E-4 | 245123 |
[ |
HSP60 | Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides... | 3 | 3 | 4.4% | 5.94E-4 | 60752 |
[ |
IMD2 | Inosine monophosphate dehydrogenase, catalyzes the rate-limiting step in GTP biosynthesis, expressio... | 2 | 2 | 4.4% | 4.33E-4 | 56530 |
[ |
DDI1 | DNA damage-inducible v-SNARE binding protein, contains a ubiquitin-associated (UBA) domain, may act ... | 2 | 2 | 4.4% | 5.29E-4 | 47354 |
[ |
MLP1 | Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the... | 10 | 11 | 4.2% | 6.65E-4 | 218454 |
[ |
PYC1 | Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly simi... | 3 | 3 | 4.2% | 2.88E-4 | 130099 |
[ |
ARO8 | Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis | 2 | 3 | 4.2% | 6.8E-4 | 56178 |
[ |
YLR227W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 5 | 6 | 4.1% | 3.87E-4 | 198404 |
[ |
DBF4 | Regulatory subunit of Cdc7p-Dbf4p kinase complex, required for Cdc7p kinase activity and initiation ... | 2 | 2 | 4.1% | 3.22E-4 | 80690 |
[ |
TKL1 | Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate... | 5 | 5 | 4.0% | 8.33E-4 | 73806 |
[ |
SAC1 | Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmemb... | 3 | 3 | 4.0% | 5.45E-4 | 71125 |
[ |
DBP9 | ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subuni... | 2 | 2 | 4.0% | 3.81E-4 | 68060 |
[ |
TYR1 | Prephenate dehydrogenase involved in tyrosine biosynthesis, expression is dependent on phenylalanine... | 2 | 2 | 4.0% | 5.01E-4 | 50923 |
[ |
YDR186C | Putative protein of unknown function; may interact with ribosomes, based on co-purification experime... | 2 | 2 | 3.9% | 2.58E-4 | 98331 |
[ |
UTP13 | Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is ... | 2 | 3 | 3.8% | 4.16E-4 | 91032 |
[ |
DED1 | ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all ye... | 3 | 3 | 3.8% | 5.63E-4 | 65553 |
[ |
URA7 | Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrog... | 2 | 3 | 3.8% | 5.87E-4 | 64710 |
[ |
SHM2 | Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrof... | 2 | 2 | 3.8% | 4.83E-4 | 52219 |
[ |
PFK1 | Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaer... | 3 | 3 | 3.7% | 3.44E-4 | 107970 |
[ |
ALA1 | Cytoplasmic and mitochondrial alanyl-tRNA synthetase, required for protein synthesis; point mutation... | 3 | 3 | 3.7% | 3.55E-4 | 107277 |
[ |
YIL108W | Putative metalloprotease | 2 | 2 | 3.7% | 3.25E-4 | 77414 |
[ |
UME1 | Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetativ... | 2 | 2 | 3.7% | 4.92E-4 | 51022 |
[ |
SSE1 | ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded protein... | 3 | 3 | 3.6% | 4.9E-4 | 77367 |
[ |
TEF4 | Translation elongation factor EF-1 gamma | 2 | 3 | 3.6% | 8.25E-4 | 46520 |
[ |
SEC61 | Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent pro... | 3 | 3 | 3.5% | 7.08E-4 | 52937 |
[ |
MIR1 | Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redunda... | 3 | 3 | 3.5% | 0.00109 | 32812 |
[ |
YOR142W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 3 | 3 | 3.4% | 1.94E-4 | 198535 |
[ |
PRT1 | eIF3b subunit of the core complex of translation initiation factor 3 (eIF3), essential for translati... | 2 | 2 | 3.4% | 2.97E-4 | 88130 |
[ |
DPS1 | Aspartyl-tRNA synthetase, primarily cytoplasmic; homodimeric enzyme that catalyzes the specific aspa... | 2 | 3 | 3.4% | 6.1E-4 | 63516 |
[ |
GFA1 | Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of glucosamine-6-P and glut... | 2 | 2 | 3.3% | 3.16E-4 | 80047 |
[ |
CTR1 | High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low... | 2 | 2 | 3.2% | 5.58E-4 | 44442 |
[ |
ACC1 | Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to f... | 6 | 6 | 3.1% | 3.04E-4 | 250351 |
[ |
RRP5 | RNA binding protein with preference for single stranded tracts of U's involved in synthesis of both ... | 5 | 6 | 3.1% | 3.93E-4 | 193133 |
[ |
CRT10 | Protein involved in transcriptional regulation of RNR2 and RNR3; expression of the gene is induced b... | 3 | 3 | 3.1% | 3.55E-4 | 109715 |
[ |
CDC48 | ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a complex with Npl4p a... | 2 | 2 | 3.0% | 2.71E-4 | 91996 |
[ |
PAT1 | Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also required for faithfu... | 2 | 2 | 3.0% | 2.85E-4 | 88495 |
[ |
FAS1 | Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty a... | 6 | 6 | 2.9% | 3.31E-4 | 228689 |
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MID2 | O-glycosylated plasma membrane protein that acts as a sensor for cell wall integrity signaling and a... | 2 | 2 | 2.9% | 6.03E-4 | 39146 |
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FUN12 | GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes a... | 2 | 2 | 2.8% | 2.26E-4 | 112268 |
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UTP21 | Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in pr... | 2 | 2 | 2.8% | 2.41E-4 | 104791 |
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FRA1 | Protein involved in negative regulation of transcription of iron regulon; forms an iron independent ... | 2 | 2 | 2.8% | 3.02E-4 | 84924 |
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FAS2 | Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty ... | 4 | 4 | 2.7% | 2.4E-4 | 206945 |
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MET5 | Sulfite reductase beta subunit, involved in amino acid biosynthesis, transcription repressed by meth... | 3 | 3 | 2.7% | 2.36E-4 | 161218 |
[ |
MES1 | Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which in... | 2 | 2 | 2.7% | 3.02E-4 | 85678 |
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UTP8 | Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subu... | 2 | 2 | 2.7% | 3.18E-4 | 80191 |
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YFL002W-A, YGR161W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 4 | 4 | 2.5% | 2.56E-4 | 202038 |
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YCL019W | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 4 | 4 | 2.5% | 2.56E-4 | 202095 |
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POM152 | Nuclear pore membrane glycoprotein; may be involved in duplication of nuclear pores and nuclear pore... | 3 | 3 | 2.5% | 2.54E-4 | 151652 |
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UBP3 | Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde tran... | 2 | 2 | 2.5% | 2.48E-4 | 101917 |
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STU2 | Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics duri... | 3 | 3 | 2.5% | 3.83E-4 | 100918 |
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ASN2 | Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in... | 2 | 2 | 2.4% | 3.96E-4 | 64593 |
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PUF3 | Protein of the mitochondrial outer surface, links the Arp2/3 complex with the mitochore during anter... | 2 | 2 | 2.3% | 2.58E-4 | 98068 |
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NUP170 | Subunit of the nuclear pore complex (NPC), required for NPC localization of specific nucleoporins; i... | 3 | 3 | 2.2% | 2.26E-4 | 169474 |
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EAF1 | Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 sub... | 2 | 2 | 2.2% | 2.31E-4 | 112502 |
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GLT1 | NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglut... | 3 | 3 | 2.1% | 1.58E-4 | 238100 |
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FKS1 | Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic sub... | 4 | 4 | 2.1% | 2.42E-4 | 214849 |
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MMS1 | Subunit of an E3 ubiquitin ligase complex involved in resolving replication intermediates or prevent... | 4 | 5 | 2.1% | 4.03E-4 | 161237 |
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CAF120 | Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in control... | 2 | 2 | 2.1% | 2.14E-4 | 118280 |
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URB1 | Nucleolar protein required for the normal accumulation of 25S and 5.8S rRNAs, associated with the 27... | 3 | 3 | 2.0% | 1.93E-4 | 203286 |
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IST2 | Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small... | 4 | 4 | 1.9% | 4.79E-4 | 105854 |
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TRA1 | Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g.... | 5 | 5 | 1.8% | 1.51E-4 | 433182 |
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YBL100W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 3 | 3 | 1.8% | 1.92E-4 | 202214 |
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KEM1 | Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved i... | 2 | 2 | 1.8% | 1.48E-4 | 175459 |
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RIA1 | Cytoplasmic GTPase involved in biogenesis of the 60S ribosome; has similarity to translation elongat... | 2 | 2 | 1.8% | 2.04E-4 | 124464 |
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MSS116 | DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns; non-polar ... | 2 | 2 | 1.8% | 3.41E-4 | 76269 |
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YLR413W | Putative protein of unknown function; YLR413W is not an essential gene | 2 | 2 | 1.8% | 3.36E-4 | 72698 |
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TFP1 | Subunit A of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase; protein prec... | 3 | 3 | 1.7% | 3.17E-4 | 118637 |
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GSC2 | Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore... | 3 | 3 | 1.6% | 1.79E-4 | 216988 |
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RPA190 | RNA polymerase I largest subunit A190 | 2 | 2 | 1.4% | 1.36E-4 | 186431 |
[ |
NUP192 | Essential structural subunit of the nuclear pore complex (NPC), localizes to the nuclear periphery o... | 2 | 2 | 1.2% | 1.35E-4 | 191534 |