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The uptake of low-density lipoprotein by cells, utilizing receptors to ensure specificity of transport. The process by which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. The process by which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of, within or between cells by means of some external agent such as a transporter or pore. The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells. The uptake of external materials by cells, utilizing receptors to ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. The directed movement of sterols within cells. A type of vesicle-mediated transport in which cells take up external materials or membrane constituents by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport
Acc: GO:0090118
Aspect: Biological Process
Desc: The uptake of low-density lipoprotein by cells, utilizing receptors to ensure specificity of transport.
Synonyms:
  • receptor-mediated endocytosis of LDL
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0090118 - receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport (interactive image map)
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Created and Maintained by: Michael Riffle