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Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function. Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference. Cleavage of double-stranded RNA to form lsiRNA (long small interfering RNA), a class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus. Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein. Any process that modulates the frequency, rate or extent of the production of small RNA involved in gene silencing by RNA. Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any process by which RNA molecules inactivate expression of target genes. The process by which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. RNA cleavage is catalyzed by a Dicer endonuclease. Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of chromatin silencing by small RNA.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: production of small RNA involved in gene silencing by RNA
Acc: GO:0070918
Aspect: Biological Process
Desc: The process by which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. RNA cleavage is catalyzed by a Dicer endonuclease.
Synonyms:
  • gene silencing by RNA, production of guide RNA
  • gene silencing by RNA, production of small RNA
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 78 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070918 - production of small RNA involved in gene silencing by RNA (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle