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Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent. The assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin and contributes to chromatin silencing. Any process that results in the assembly of chromatin into heterochromatin and contributes to chromatin silencing. Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. The process by which an siRNA-associated RNA-induced silencing complex (siRISC) associates with nascent transcripts and RNA polymerase to induce the formation of heterochromatin.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: heterochromatin formation involved in chromatin silencing
Acc: GO:0070869
Aspect: Biological Process
Desc: Any process that results in the assembly of chromatin into heterochromatin and contributes to chromatin silencing.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070869 - heterochromatin formation involved in chromatin silencing (interactive image map)
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